4-Acetamido-N-(2-(Diethylamino)Ethyl)Benzamide Hydrochloride 4-乙酰氨基-N-(2-(二乙氨基)乙基)苯甲酰胺盐酸盐

CAS 34118-92-8 MFCD00012501

化学结构图

34118-92-8
SMILES: Cl.CC(=O)NC1C=CC(=CC=1)C(=O)NCCN(CC)CC

化学属性

Mol. FormulaC15H24ClN3O2
Mol. Weight314
Melting Point184-186 °C(lit.)

别名和识别编码

Chemical Name4-Acetamido-N-(2-(Diethylamino)Ethyl)Benzamide Hydrochloride
Synonym N-乙酰普卡胺 盐酸盐 NAPA 乙酰卡尼 盐酸盐 N-乙酰普鲁卡因胺 盐酸盐
MDL NumberMFCD00012501
PubChem Substance ID24852214
CAS Number34118-92-8
EC Number251-831-2
Chemical Name Translation4-乙酰氨基-N-(2-(二乙氨基)乙基)苯甲酰胺盐酸盐
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分类

  • {SNA} A-AM, Amides, Bioactive Small Molecules, Building Blocks, C8 to C20+, Carbonyl Compounds, Cell Biology, Chemical Synthesis, Organic Building Blocks
  • A-AM, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Ion Channels, Monovalent Ion Channels, Potassium Channel Modulators, Voltage-gated Ion Channels
  • {SNA} A-AM, Bioactive Small Molecule Alphabetical Index, Ion Channels, Monovalent Ion Channels, Potassium Channel Modulators, Voltage-gated Ion Channels, 生物活性小分子, 细胞信号转导和神经科学, 细

相关文献及参考

  • Kamath, B.L., et al., Pharmacokinetics of procainamide and N-acetylprocainamide in rats J. Pharm. Sci. 70 , 299-302, (1981)
  • Jung, D., et al., Disposition of procainamide and N-acetylprocainamide in protein-calorie malnutrition Drug Metab. Dispos. 13 , 359-63, (1985)
  • Geelen, P., et al., Concomitant block of the rapid (I(Kr)) and slow (I(Ks)) components of the delayed rectifier potassium current is associated with additional drug effects on lengthening of cardiac repolarization. J. Cardiovasc. Pharmacol. Ther. 4 , 143, (1999)
  • Richardson, B., et al., N-acetylprocainamide is a less potent inducer of T cell autoreactivity than procainamide. Arthritis Rheum. 31 , 995-999, (1998) 摘要
  • Komeichi, K., et al., Effects of N-acetylprocainamide and sotalol on ion currents in isolated guinea-pig ventricular myocytes. Eur. J. Pharmacol. 187 , 313-322, (1990) 摘要
  • Merck 14 ,20
  • FT-IR 2 (2), 3004:B / FT-NMR 1 (2), 1398:A / IR-Spectra (3), 1080:E / RegBook 1 (2), 2021:F / Structure Index 1 , 322:A:7

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

系列性分类

  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Carbonyl Compounds 羰基化合物
  5. Amides - Carbonyl Compounds
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Ion Channels - Cell Signaling and Neuroscience
  5. Voltage-gated Ion Channels - Ion Channels
  6. Monovalent Ion Channels - Voltage-gated Ion Channels
  7. Potassium Channel Modulators - Monovalent Ion Channels
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Ion Channels - Cell Signaling and Neuroscience
  5. Voltage-gated Ion Channels - Ion Channels
  6. Monovalent Ion Channels - Voltage-gated Ion Channels
  7. Potassium Channel Modulators - Monovalent Ion Channels
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Carbonyl Compounds 羰基化合物
  5. Aldehydes
  6. C9
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Cell Signaling and Neuroscience
  4. Neuroscience
  5. Ion Channels
  6. Ligand-Gated Ion Channels
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Cell Signaling and Neuroscience
  4. Ion Channels
  5. Voltage-gated Ion Channels
  6. Monovalent Ion Channels
  7. Ionophores

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