1,4-Diaminobutane Dihydrochloride 1,4-丁二胺双盐酸盐

CAS 333-93-7 MFCD00012526

化学结构图

333-93-7
SMILES: Cl.Cl.NCCCCN

化学属性

Mol. FormulaNH2(CH2)4NH2
Mol. Weight161
Density1.472
Melting Point280
TSCAYes
SolubilityH2O: 100 mg/mL
Appearance powder

别名和识别编码

Chemical Name1,4-Diaminobutane Dihydrochloride
CAS Number333-93-7
Alfabeta NameDIAMINOBUTANEDIHYDROCHLORIDE 14-,
MDL NumberMFCD00012526
Synonym 1, 1,4-Butanediamine dihydrochloride 1,4-Butanediamine dihydrochloride, Putrescine dihydrochloride 1,4-Butanediamine, dihydrochloride 1,4-DIAMINOBUTANE 2HCL 1,4-DIAMINOBUTANE DIHYDROCHLORIDE 1,4-DIAMINOBUTANE DIHYDROCHLORIDE 98+% 1,4-DIAMINOBUTANE HYDROCHLORIDE 1,4-Diaminob 1,4-Diaminobutan Dihydrochlorid 1,4-Diaminobutane dihydrochloride 1,4-Diaminobutane, 1,4-丁二胺 二盐酸盐 1,4-丁二胺 二盐酸盐 1,4-二氨基丁烷 二盐酸盐 四亚甲基二胺 二盐酸盐 1,4-丁二胺双盐酸盐 1,4-二氨基丁烷 1,4-二氨基丁烷/腐胺二盐酸盐 1,4-二氨基丁烷盐酸盐 Butane, Putrescindihydrochlorid Putrescine dihydrochloride Putrescine dihydrochloride; 1,4-Butanediamine dihydrochloride b {} {} {} {} {uni_ha 腐肉胺盐酸盐
EC Number206-375-9
Beilstein Registry Number3906680
PubChem Substance ID87566825
Merck Number14,7947
Reaxys-RN3906680
Chemical Name Translation1,4-丁二胺双盐酸盐
LabNetwork Molecule IDLN00174332
InChIInChI=1S/C4H12N2.2ClH/c5-3-1-2-4-6;;/h1-6H2;2*1H
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分类

  • {SNA} Amino Acid, Bioactive Small Molecule Alphabetical Index, Excitatory Amino Acids, Neuroscience, Neurotransmission, Neurotransmitters, Other Excitatory Amino Acids, PI-PZ, 代谢组学, 代谢通路, 代谢通路图中的代谢产物和辅酶分子,
  • {SNA} Miscellaneo
  • {SNA} Amino Acid,
  • {SNA} Bioactive Small Molecules, Cell Biology, Cell Culture, Hordeum vulgare (Barley), Miscellaneous Reagents and Supplements,
  • {SNA} Miscellaneous Reagents and Supplements, 细胞培养, 试剂和添加剂
  • {SNA} Amino Acid, Bioactive Small Molecule Alphabetical Index, Excitatory Amino Acids, Neuroscience, Neurotransmission, Neurotransmitters,

产品应用

  • 结合到NMDA受体的聚胺调节点，强化NMDA感应电流。

相关文献及参考

  • [2]. E B Sequerra, et al. Putrescine as an important source of GABA in the postnatal rat subventricular zone. Neuroscience. 2007 May 11;146(2):489-93.
  • Merck: 14,7947
  • Merck: 14,7947 Beilstein:4,264
  • Short: EINECS
  • Short: III/5a
  • [1]. Hauschild MZ. Putrescine (1,4-diaminobutane) as an indicator of pollution-induced stress in higher plants: barley and rape stressed with Cr(III) or Cr(VI). Ecotoxicol Environ Saf. 1993 Oct;26(2):228-47.
  • [1]. Hauschild MZ. Putrescine (1,4-diaminobutane) as an indicator of pollution-induced stress in higher plants: barley and rape stressed with Cr(III) or Cr(VI). Ecotoxicol Environ Saf. 1993 Oct;26(2):228-47.
  • [2]. E B Sequerra, et al. Putrescine as an important source of GABA in the postnatal rat subventricular zone. Neuroscience. 2007 May 11;146(2):489-93.

安全信息

Warnings IRRITANT
Signal word Warning
GHS Symbol
WGK Germany3
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S37 Wear suitable gloves 戴适当手套；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P302+P350
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P332+P313
  • P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
RTECSEJ7280000
Storage condition 2-8°C Hygroscopic
Hazard Codes Xi 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1400 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   PWPSA8 Proceedings of the Western Pharmacology Society.  (Univ. of
   California Dept. of Pharmacology, Los Angeles, CA 90024)  V.1-    1958-
   Volume(issue)/page/year: 29,141,1986

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 510 mg/kg
TOXIC EFFECTS :
   Behavioral - antipsychotic
   Lungs, Thorax, or Respiration - respiratory depression
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1880 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 25,489,1983

TYPE OF TEST            : LD30 - Lethal Dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AGACBH Agents and Actions, A Swiss Journal of Pharmacology.  (Birkhaeuser
   Verlag, POB 133, CH-4010 Basel, Switzerland)  V.1-    1969/70-
   Volume(issue)/page/year: 14,228,1984

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Human HeLa cell
DOSE/DURATION           : 2 mmol/L
REFERENCE :
   JCLLAX Journal of Cellular Physiology.  (Alan R. Liss, Inc., 41 E. 11th St.,
   New York, NY 10003) V.67-    1966-  Volume(issue)/page/year: 78,217,1971

其他信息

  • Sigma Aldrich:333-93-7(sigmaaldrich)
  • Alfa Aesar:1,4-二氨基丁烷二盐酸盐,98% 1,4-Diaminobutane dihydrochloride, 99%(333-93-7)
  • 图谱信息:1,4-丁二胺二盐酸盐(333-93-7)红外图谱(IR1) 1,4-丁二胺二盐酸盐(333-93-7)质谱(MS) 1,4-丁二胺二盐酸盐(333-93-7)红外图谱(IR2)
  • 检测方法:T,NMR
  • MOL 文件:333-93-7.mol
  • 敏感性:Hygroscopic
  • 1,4-丁二胺二盐酸盐价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 D0081 1,4-二氨基丁烷二盐酸盐 1,4-Diaminobutane Dihydrochloride 25G 527元 2014/06/02 D0081 1,4-二氨基丁烷二盐酸盐 1,4-Diaminobutane Dihydrochloride 500G 3920元 2010/06/21 215110250 1,4-丁二胺二盐酸盐 1,4-Diaminobutane dihydrochloride 99+% 25 GR 587元
  • TCI Shanghai:1,4-二氨基丁烷二盐酸盐 1,4-Diaminobutane Dihydrochloride,>;98.0%(T)(333-93-7)
  • Acros Organics:1,4-二氨基丁烷/腐胺二盐酸盐 1,4-Diaminobutane dihydrochloride, 99+%(333-93-7)
  • 用途一:结合到NMDA受体的聚胺调节点，强化NMDA感应电流。

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Bioactive Small Molecules - Cell Biology
  4. D-DIF - Bioactive Small Molecules
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Bioactive Small Molecules - Cell Biology
  4. P - Bioactive Small Molecules
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Nitrogen Compounds 氮化合物
  5. Amine Salts - Nitrogen Compounds
  1. Life Science 生命科学
  2. Metabolomics 代谢组学
  3. Metabolic Pathways - Metabolomics
  4. Metabolites and Cofactors on the Metabolic Pathways Chart - Metabolic Pathways
  5. Amino Acid - Metabolites and Cofactors on the Metabolic Pathways Chart
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Nitrogen Compounds 氮化合物
  5. Amidates/Imidates
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Cell Culture
  4. Lipids and Lipid Carriers
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Microscopy Reagents
  4. Stains and Dyes
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Reagents and Supplements
  4. Lipids and Lipid Carriers
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Cell Culture
  4. Reagents and Supplements
  5. Lipids and Lipid Carriers
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Metabolomics
  4. Metabolic Pathways
  5. Metabolites and Cofactors on the Metabolic Pathways Chart
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Enzymes, Inhibitors, and Substrates
  4. Metabolomics
  5. Metabolic Pathways
  6. Metabolites and Cofactors on the Metabolic Pathways Chart
  1. Medical Research Areas
  2. Metabolism
  3. Endogenous Metabolite  (内源性代谢物)

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