Nα-p-Tosyl-L-Arginine Methyl Ester Hydrochloride NA-P-甲苯磺酰-L-精氨酸甲酯盐酸盐

CAS 1784-03-8 MFCD00012578

化学结构图

1784-03-8
SMILES: Cl.[H]/N=C(\N)NCCCC(NS(=O)(=O)c1ccc(C)cc1)C(=O)OC

化学属性

Mol. FormulaC14H22N4O4S·HCl
Mol. Weight379
Melting Point146-150
Density1.13
Solubilitymethanol: 50 mg/mL, clear, colorless
Refractive index-14 ° (C=4, H2O)

别名和识别编码

Chemical NameNα-p-Tosyl-L-Arginine Methyl Ester Hydrochloride
Synonym 4,5-羟基萘乙烯 N-A-P-TOSYL-L-ARGININE METHYL ESTER HYDROCHLORIDE N-ALPHA-P-TOSYL-L-ARGININE METHYL ESTER HYDROCHLORIDE SALT N-ALPHA-TOSYL-L-ARGININE METHYL ESTER HYDROCHLORIDE SALT N-Α-甲苯磺酰-L-精氨酸甲酯盐酸盐 N-Α-甲苯磺酰精氨酸甲酯盐酸盐 N-对甲苯磺酰基-L-精氨酸甲酯盐酸盐 NA-P-甲苯磺酰-L-精氨酸甲酯盐酸盐 NALPHA-P-TOLUENESULFONYL-L-ARGININE METHYL ESTER HYDROCHLORIDE Nalpha-4-tosyl-L-arginine methyl ester hydrochloride NΑ-P-甲苯磺酰基-L-精氨酸甲酯盐酸盐 P-TOLUENESULFONYL-L-ARGININE METHYL ESTER HCL P-TOLUENESULFONYL-L-ARGININE METHYL ESTER HYDROCHLORIDE TOS-ARGININE-OME HCL TOSYL-L-ARGININE METHYL ESTER HYDROCHLORIDE
Beilstein Registry Number3922357
PubChem Substance ID2723792
CAS Number1784-03-8
EC Number217-235-1
MDL NumberMFCD00012578
Reaxys-RN10499395
Chemical Name TranslationNA-P-甲苯磺酰-L-精氨酸甲酯盐酸盐
InChIKeyJIQFFACVQXXHMY-UHFFFAOYSA-N
LabNetwork Molecule IDLN00191633
InChIInChI=1S/C14H22N4O4S.ClH/c1-10-5-7-11(8-6-10)23(20,21)18-12(13(19)22-2)4-3-9-17-14(15)16;/h5-8,12,18H,3-4,9H2,1-2H3,(H4,15,16,17);1H/t12-;/m0./s1
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分类

  • {SA} Biochemicals and Reagents, Enzyme Substrates, Enzymes, Inhibitors, and Substrates, Kallikrein, Plasma & Blood Proteins, Plasmin, Proteins and Derivatives,
  • {SNA} Am
  • Amino Acid Derivatives, Amino Acids,
  • {SNA} Amino Acids, Amino Acids & Derivatives, Arginine, Chemical Biology, Chemical Synthesis, Enzyme Substrates, I - Z, Kallikrein, Modified Amino Acids, Peptide Chemistry, Plasmin, Substrates by Enzyme, Subtilisin, Thrombin, Trypsin Substrates, Urinary esterase, 生化试剂, 酶、抑制剂和底物

产品应用

  • 胰蛋白酶(trypsin)、凝血酶(thrombin)、血纤维蛋白溶酶（plasmin） 和其它蛋白酶的底物。

相关文献及参考

  • Beil. 11 ,IV,449
  • 2. Castellino, F.J. and Sodetz, J.M Meth. Enzymol. 45 , 273, (1976) 摘要
  • Zeng X, Sigoillot F, Gaur S, Choi S, Pfaff KL, Oh DC, Hathaway N, Dimova N, Cuny GD, King RW., Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage. Cancer Cell 18 , 382-95, (2010) 摘要
  • Klomklao S, Benjakul S, et al., Purification and characterization of trypsin from the spleen of tongol tuna ( Thunnus tonggol ). J. Agric. Food Chem. 54 , 5617-5622, (2006) 摘要
  • Chen Y, Wu M, Wang K, et al., Vinyl functionalized silica hybrid monolith-based trypsin microreactor for on line digestion and separation via thiol-ene "click" strategy. J. Chromatogr. A. 1218 , 7982-7988, (2011) 摘要
  • Beilstein: 11,IV,449

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Signal word Warning
GHS Symbol
Safety Statements
  • S22 Do not breathe dust 不要吸入粉尘；
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Storage condition -20°C 2-8°C储存

其他信息

  • NA-P-甲苯磺酰-L-精氨酸甲酯盐酸盐价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 T0330 Nα-对甲苯磺酰基-L-精氨酸甲酯盐酸盐 Nalpha-Tosyl-L-arginine Methyl Ester Hydrochloride 1G 117元 2014/06/02 T0330 Nα-对甲苯磺酰基-L-精氨酸甲酯盐酸盐 Nalpha-Tosyl-L-arginine Methyl Ester Hydrochloride 25G 954元 2010/06/21 139200050 NA-P-甲苯磺酰-L-精氨酸甲酯盐酸盐 Nalpha-4-Tosyl-L-arginine methyl ester hydrochloride 99% 5 GR 427元
  • TCI Shanghai:Nα-对甲苯磺酰基-L-精氨酸甲酯盐酸盐 Nalpha-Tosyl-L-arginine Methyl Ester Hydrochloride,>;98.0%(T)(1784-03-8)
  • F:3-10
  • Sigma Aldrich:1784-03-8(sigmaaldrich)
  • 用途一:胰蛋白酶(trypsin)、凝血酶(thrombin)、血纤维蛋白溶酶（plasmin） 和其它蛋白酶的底物。
  • 比旋光度:-14 ° (c=4, H2O)
  • Acros Organics:Nα-p-甲苯磺酰基-L-精氨酸甲酯盐酸盐 Nalpha-4-Tosyl-L-arginine methyl ester hydrochloride, 99%(1784-03-8)
  • MOL 文件:1784-03-8.mol

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Amino Acids 氨基酸
  4. Modified Amino Acids - Amino Acids
  5. I - Z - Modified Amino Acids
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Substrates - Enzymes, Inhibitors, and Substrates
  5. Substrates by Enzyme - Enzyme Substrates
  6. Plasmin - Substrates by Enzyme
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Substrates - Enzymes, Inhibitors, and Substrates
  5. Substrates by Enzyme - Enzyme Substrates
  6. Urinary esterase - Substrates by Enzyme
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Amino Acids 氨基酸
  4. Modified Amino Acids - Amino Acids
  5. Other Protected Amino Acids
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Albumins and Transport Proteins
  4. Albumin
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Amino Acids
  4. Amino Acids
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Enzymes, Inhibitors, and Substrates
  4. Enzyme Substrates
  5. Substrates by Enzyme
  6. Isoquinoline 1-Oxidoreductase
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Enzymes, Inhibitors, and Substrates
  4. Enzyme Substrates
  5. Substrates by Enzyme
  6. Peroxidase Substrates
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Enzymes, Inhibitors, and Substrates
  4. Enzyme Substrates
  5. Substrates by Enzyme
  6. Quinaldate 4-oxidoreductase
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Enzymes, Inhibitors, and Substrates
  4. Enzyme Substrates
  5. Substrates by Enzyme
  6. Thiophene-2-carbonyl-CoA monooxygenase
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Enzymes, Inhibitors, and Substrates
  4. Enzyme Substrates
  5. Substrates by Enzyme
  6. Thrombin
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Enzymes, Inhibitors, and Substrates
  4. Enzyme Substrates
  5. Substrates by Enzyme
  6. Urease
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Enzymes, Inhibitors, and Substrates
  4. Analytical Enzymes
  5. Trypsin
  6. Trypsin Inhibitors

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