Serotonin Hydrochloride 3-(2-氨基乙基)-5-羟基吲哚盐酸盐

CAS 153-98-0 MFCD00012686

化学结构图

153-98-0
SMILES: Cl.NCCc1c[nH]c2ccc(O)cc12

化学属性

Mol. FormulaC10H12N2O·HCl
Mol. Weight213
Density1.422
Melting Point167-172
TSCANo
SolubilitySoluble in water (17 mg/ml), methanol, ethanol (5.3 mg/ml), 0.1 M HCl (22 mg/ml), aqueous acid, and DMSO (100 mM). Insoluble in chloroform, and ether.
Stability对光和湿度敏感
Appearance powder

别名和识别编码

Chemical NameSerotonin Hydrochloride
CAS Number153-98-0
Synonym Serotonin hydrochloride {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} 3-(2-Aminoethyl)-5-hydroxyindole hydrochloride, 5-HT, 5-Hydroxytryptamine hydrochloride
MDL NumberMFCD00012686
EC Number244-464-4
Beilstein Registry Number3570963
Merck Number8462
PubChem Substance ID160436
Chemical Name Translation3-(2-氨基乙基)-5-羟基吲哚盐酸盐
Reaxys-RN3570963
LabNetwork Molecule IDLN00193951
InChIInChI=1S/C10H12N2O.ClH/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10;/h1-2,5-6,12-13H,3-4,11H2;1H
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分类

  • {SNA} Agonists, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Neuroscience, Neurotransmission, Neurotransmitters, Nutrition Research, Phytochemicals by Plant (Food/Spice/Herb), Proteins and Derivatives, S, Serotonergics, Serotonergics - Agonists, Theobroma cacao (Chocolate)
  • {SNA} Agonists, Bioactive Small Molecules, Biochemicals and Reagents, Cell Signaling and Neuroscience, GPCR Modulators, GPCR Proteins, Modulators and Antibodies,
  • {SNA
  • {SNA} Agonists,

产品应用

  • A tryptophan based amino acid neurotransmitter.

相关文献及参考

  • Merck:14,8463
  • Merck:14,8463 Beilstein:22(3/4)5668
  • Kuraishi, Y., et al.: Biol. Pharm. Bull., 31, 2143 (2008); Morera, E., et al.: Bioorg. Med. Chem. Lett., 19, 6806 (2009);

安全信息

Signal word Warning
GHS Symbol
WGK Germany3
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
  • S22 Do not breathe dust 不要吸入粉尘；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P316
  • P301+P317
  • P302+P352
  • P304+P340
  • P305+P351+P338
  • P317
  • P319
  • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
  • P330 Rinse mouth. 漱口
  • P332+P317
  • P337+P317
  • P362+P364
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H301 Toxic if swallowed 吞食有毒
  • H302 Harmful if swallowed 吞食有害
  • H312 Harmful in contact with skin 皮肤接触有害
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H332 Harmful if inhaled 吸入有害
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
RTECSNM2571000
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Packing GroupIII
UN Number UN2811 2811
Storage condition 储存温度 2-8℃ Light Sensitive & Hygroscopic 2-8°C 对光和湿度敏感，密封2-8°C避光保存 储存温度 -20°C,充氩保存
Hazard Codes Hazard;Xn Xn
Hazard Class6.1

其他信息

  • 图谱信息:5-羟基色胺盐酸盐(153-98-0)核磁图( 13 CNMR) 5-羟基色胺盐酸盐(153-98-0)红外图谱(IR2) 5-羟基色胺盐酸盐(153-98-0)红外图谱(IR1) 5-羟基色胺盐酸盐(153-98-0)核磁图( 1 HNMR) 5-羟基色胺盐酸盐(153-98-0)质谱(MS)
  • 溶于水和甲醇。溶解度：17 mg/mLH2O；22 mg/mL0.1 M HCl；5.3 mg/mL乙醇。
  • Alfa Aesar:5-羟色胺盐酸盐,99% Serotonin hydrochloride, 99%(153-98-0)
  • Acros Organics:5-羟色胺盐酸盐 Serotonin hydrochloride, 99%(153-98-0)
  • 5-羟基色胺盐酸盐价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 S0370 血清胺盐酸盐 Serotonin Hydrochloride 5G 1460元 2014/06/02 S0370 血清胺盐酸盐 Serotonin Hydrochloride 25G 4700元 2010/06/21 215021000 5-羟基色胺盐酸盐 Serotonin hydrochloride 99% 100 MG 834元
  • F:3-8-10
  • color:white to off-white
  • Sigma Aldrich:153-98-0(sigmaaldrich)
  • MOL 文件:153-98-0.mol
  • 用途一:神经传递介质。
  • 敏感性:Light Sensitive & Hygroscopic
  • Serotonin hydrochloride is the salt form of Serotonin, a monoamine neurotransmitter biochemically derived from tryptophan. This neurotransmitter is located in the central nervous system and functions as an endogenous SR (serotonin receptor) agonist in a variety of biochemical processes. In the majority of the human bodies, serotonin is located in enterochromaffin (”Kulchitsky cells”). Serotonin is found in the gastrointestinal tract and platelets. Furthermore, Serotonin functions as a growth factor in some cells and facilitates wound healing in conjunction with platelets. Serotonin is thought to be a key component in the regulation of moods, cognition, and personality traits. As a result, this compound is essential in studying the variations in these traits.
  • 存储注意事项:光敏感
  • TCI Shanghai:5-羟色胺盐酸盐 Serotonin Hydrochloride,>;97.0%(T)(153-98-0)
  • 下游产品:5-(2-(4-(1,2-苯并异噻唑-3-基)-1-哌嗪基)乙基)-6-氯-1,3-二氢-2(1H)-吲哚-2-酮盐酸盐

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Bioactive Small Molecules - Cell Biology
  4. S - Bioactive Small Molecules
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Indazoles 吲唑
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Indoles 吲哚
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Amino Acids 氨基酸
  4. Modified Amino Acids - Amino Acids
  5. Amino alcohols
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Chemicals by Class 化学分类法
  4. Indoles