Swainsonine 苦马豆素

CAS 72741-87-8 MFCD00017554

化学结构图

72741-87-8
SMILES: O[C@@H]1CN2CCC[C@@H](O)[C@@H]2[C@@H]1O

化学属性

Mol. FormulaC8H15NO3
Mol. Weight173.21

别名和识别编码

Chemical NameSwainsonine
CAS Number72741-87-8
Synonym (-)-Swainsonine (1S,2R,8R,8aR)-1,2,8-Octahydroindolizidinetriol 8?,?-Octahydroindolizidine-1?,2?,8?-triol Swainsonine Tridolgosir
MDL NumberMFCD00017554
Beilstein Registry Number4175740
PubChem Substance ID24899832
Chemical Name Translation苦马豆素
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分类

  • {SNA} Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Inhibitors, Inhibitors and Substrates, L to O, Mannosidase, alpha-, 分子生物学, 生化试剂, 糖生物学, 翻译后修饰, 蛋白质组学, 酶、抑制剂和底物
  • Glycosidase Inhibitors
  • {SNA} Antibiotics A to Z, Antibiotics N-S, Antibiotics by Application, Antineoplastic and Immunosuppressive Antibiotics, Inhibits an Enzyme, Mechanism of Action, 抗生素, 生化试剂
  • {SNA} Biochemicals and Reagents, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, Glycobiology,
  • Inhibitors

产品应用

  • Swainsonine is a plant alkaloid derived from Swainsona canescens (a leguminous plant). It is a reversible, active-site directed inhibitor of a-mannosidase at concentrations of 5-10mM. At acid pH, swa

相关文献及参考

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安全信息

GHS Symbol
WGK Germany3
Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
Hazard statements
  • H332 Harmful if inhaled 吸入有害
  • H302 Harmful if swallowed 吞食有害
  • H312 Harmful in contact with skin 皮肤接触有害
RTECSNM2408666
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes Xn
Safety Statements
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
Risk Statements
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害

系列性分类

  1. Life Science 生命科学
  2. Antibiotics 抗生素
  3. Antibiotics A to Z - Antibiotics
  4. Antibiotics N-S - Antibiotics A to Z
  1. Life Science 生命科学
  2. Antibiotics 抗生素
  3. Antibiotics A to Z - Antibiotics
  4. Antibiotics N-S - Antibiotics A to Z
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Inhibitors - Enzymes, Inhibitors, and Substrates
  5. Enzyme Inhibitors by Type - Enzyme Inhibitors
  6. Substrate Analogs - Enzyme Inhibitors by Type
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Inhibitors - Enzymes, Inhibitors, and Substrates
  5. Enzyme Inhibitors by Enzyme - Enzyme Inhibitors
  6. L to O - Enzyme Inhibitors by Enzyme
  7. Mannosidase, alpha- - L to O
  1. Life Science 生命科学
  2. Proteomics 蛋白质组学
  3. Post-Translational Modification - Proteomics
  4. Glycobiology - Post-Translational Modification
  5. Inhibitors and Substrates - Glycobiology
  6. Inhibitors - Inhibitors and Substrates

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