DL-o-Tyrosine 2-氨基-3-(2-羟基苯基)丙酸

CAS 2370-61-8 MFCD00021725

化学结构图

2370-61-8
SMILES: N[C@@H](Cc1ccccc1O)C(=O)O

化学属性

Mol. FormulaC9H11NO3
Mol. Weight181.19
Melting Point-260 °C
TSCANo
Boiling Point369 °C at 760 mmHg

别名和识别编码

Chemical NameD,L-o-Tyrosine
CAS Number2370-61-8
Synonym DL-O-Tyrosine {LY} DL-O-Tyrosine {} {LY} DL-O-Tyrosine {} {} {LY} DL-O-Tyrosine {} {} {} {LY} DL-O-Tyrosine {} {} {} {} {LY} DL-O-Tyrosine {} {} {} {} {} { {} {} {} {} {} {LY} DL-O-Tyrosine {} {} {} {} {} {} {LY} DL-O-Tyrosine {} {} {} {} {} {} {} {LY} DL-O-Tyrosine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} DL-O-Tyrosine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} DL-O-Tyrosine {} {} {} {} {} {} {} {} {} {} {LY} DL-O-Tyrosine {} {} {} {} {} {} {} {} {} {} {} {LY} DL-O-Tyrosine {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {LY} DL-O-Tyrosine {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} DL-O-Tyrosine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} DL-O-Tyrosine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} DL-O-Tyrosine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
MDL NumberMFCD00021725
PubChem Substance ID91482
Beilstein Registry Number2805789
EC Number219-134-8
Reaxys-RN2805789
Chemical Name Translation2-氨基-3-(2-羟基苯基)丙酸
Wiswesser Line NotationQVYZ1R BQ
LabNetwork Molecule IDLN00195526
Canonical SMILESNC(CC1=CC=CC=C1O)C(O)=O
InChIInChI=1S/C9H11NO3/c10-7(9(12)13)5-6-3-1-2-4-8(6)11/h1-4,7,11H,5,10H2,(H,12,13)
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分类

  • {SNA} Analytical Standards,
  • Amino Acids & Derivatives
  • {SNA} Additional Standards, Analytical Standards, Chemical Biology, Chemical Class, Chemical Synthesis, Peptide Chemistry, Phenols, Tyrosine Derivatives, Unnatural Amino Acids & Derivatives, 分析/色谱
  • {SNA} Chemical Class, Analytical Standards,

产品应用

  • A metabolite of Phenylalanine

相关文献及参考

  • Tsugita, A., et al.: Eur. J. Biochem., 124, 585 (1982),
  • Li M, Carlson S, Kinzer JA, Perpall HJ., HPLC and LC-MS studies of hydroxylation of phenylalanine as an assay for hydroxyl radicals generated from Udenfriend's reagent. Biochem. Biophys. Res. Commun. 312 , 316-322, (2003)
  • Klipcan L, Moor N, Kessler N, Safro MG., Eukaryotic cytosolic and mitochondrial phenylalanyl-tRNA synthetases catalyze the charging of tRNA with the meta-tyrosine. Proc. Natl. Acad. Sci. U. S. A. 106 , 11045-11048, (2009)
  • Saravanabhavan G, Blais E, et al., A high performance liquid chromatography-electrochemical array method for the measurement of oxidative/nitrative changes in human urine. J. Chromatogr. A. 1217 , 3269-3274, (2010)
  • Syslová K, Kačer P, Kuzma M, et al., LC-ESI-MS/MS method for oxidative stress multimarker screening in the exhaled breath condensate of asbestosis/silicosis patients. J. Breath Res. 4 , 017104, (2010)

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P350
  • P302+P352
  • P302+P352+P332+P313+P362+P364
  • P304+P340
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
  • P319
  • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
  • P332+P313
  • P332+P317
  • P337+P313
  • P337+P317
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
  • P362+P364
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Hazard Codes Xi
RTECSYP2285000
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Signal word Warning {} {} {} {} {TCI}
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S37 Wear suitable gloves 戴适当手套；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 320 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#02426

Storage condition 2-8°C, stored under nitrogen {LY} 2-8°C, stored under nitrogen RT, stored under nitrogen {} {LY} 2-8°C, stored under nitrogen {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitro

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Amino Acids 氨基酸
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Chromatography - Analytical Standards
  4. Food & Beverage Standards - Chromatography
  5. Organic Acids - Food & Beverage Standards
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Chromatography - Analytical Standards
  4. Food & Beverage Standards - Chromatography
  5. Food Residue Analysis - Food & Beverage Standards
  1. Chemical Synthesis 化学合成
  2. Chemical Biology 生物化学
  3. Peptide Chemistry 多肽化学
  4. Unnatural Amino Acid Derivatives 人工合成氨基酸
  5. Tyrosine Derivatives - Unnatural Amino Acid Derivatives

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