Succinylsulfathiazole 琥珀酰磺胺噻唑

CAS 116-43-8 MFCD00022437

化学结构图

116-43-8
SMILES: O=C(O)CCC(=O)Nc1ccc(S(=O)(=O)Nc2nccs2)cc1

化学属性

Mol. FormulaC13H13N3O5S2
Mol. Weight355
Appearance 白色或黄色结晶性粉末，无臭，味苦。不明显报导为184~186℃或约190℃同时分解，遇光变暗，琥珀酰磺胺噻唑(116-43-8)几乎不溶于水，易溶于氢氧化碱和碳酸盐溶液中，难溶于乙醇，不溶于乙醚。

别名和识别编码

Chemical NameSuccinylsulfathiazole
MDL NumberMFCD00022437
CAS Number116-43-8
Beilstein Registry Number349989
EC Number204-141-0
PubChem Substance ID5315
Synonym 2-(N-SUCCINYLSULFANILAMIDO)THIAZOLE 2-(n(4)-succinylsulfanilamido)thiazole 4'-(2-THIAZOLYLSULFAMOYL)-SUCCINANILIC ACID 4'-(2-thiazolylsulfamoyl)succinanilic acid 4-oxo-4-((4-((2-thiazolylamino)sulfonyl)phenyl)amino)-butanoicaci 4’-(2-thiazolylsulfamoyl)-succinanilicaci Butanoic acid, 4-oxo-4-((4-((2-thiazolylamino)sulfonyl)phenyl)amino)- Colistatin Cremosuxidine KAOXIDINE Kaoxidin Kaoxidine Rolsul SST SUCCINYLSULFATHIAZOLE SULFASUXIDINE SULFENTERONE Succinylsulfathiazole Succinylsulphathiazole Sulfadigesin Sulfasuccidin Sulfasuccidine Sulfasuccinil Sulfasuccithiazole Sulfasuxidine Sulfenterone THIACYL {
Chemical Name Translation琥珀酰磺胺噻唑
Reaxys-RN349989
Merck Number8877
Wiswesser Line NotationT5N CSJ BMSWR DMV2VQ
LabNetwork Molecule IDLN00195274
InChIInChI=1S/C13H13N3O5S2/c17-11(5-6-12(18)19)15-9-1-3-10(4-2-9)23(20,21)16-13-14-7-8-22-13/h1-4,7-8H,5-6H2,(H,14,16)(H,15,17)(H,18,19)
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分类

  • {SNA} Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics N-S, Chemical Structure Class, Inhibits an Enzyme, Interferes with DNA Synthesis, L - Z, Mechanism of Action, Spectrum of Activity, Sulfonamides
  • {SNA} Antibacterial, Antibiotics A to Z,

安全信息

GHS Symbol
WGK Germany3
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P285 In case of inadequate ventilation wear respiratory protection. 在通风不足的情况下，戴呼吸防护。
  • P302+P352
  • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
  • P333+P313
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
RTECSWM4767000
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Safety Statements
  • S22 Do not breathe dust 不要吸入粉尘；
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
Hazard Codes Xn
Risk Statements
  • R42/43
Packing GroupIII
Hazard Class6.1(b)
UN Number 3249 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5700 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 75,231,1942

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 10 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 7,151,1981

其他信息

  • Sigma Aldrich:116-43-8(sigmaaldrich)
  • MOL 文件:116-43-8.mol
  • 琥珀酰磺胺噻唑价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/04/16 S0581 丁二酰磺胺噻唑水合物 Succinylsulfathiazole Hydrate 500G 2260元 2011/04/16 S0581 丁二酰磺胺噻唑水合物 Succinylsulfathiazole Hydrate 25G 286元
  • 琥珀酰磺胺噻唑价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 S0581 丁二酰磺胺噻唑水合物 Succinylsulfathiazole Hydrate 25G 347元 2011/04/16 S0581 丁二酰磺胺噻唑水合物 Succinylsulfathiazole Hydrate 500G 2260元
  • MSDS 信息:p-2-Thiazolylsulfamoylsuccinanilic acid(116-43-8).msds
  • 图谱信息:琥珀酰磺胺噻唑(116-43-8)红外图谱(IR1) 琥珀酰磺胺噻唑(116-43-8)红外图谱(IR2) 琥珀酰磺胺噻唑(116-43-8)质谱(MS)
  • TCI Shanghai:丁二酰磺胺噻唑水合物 Succinylsulfathiazole Hydrate,>;97.0%(LC)(T)(116-43-8)

系列性分类

  1. Life Science 生命科学
  2. Antibiotics 抗生素
  3. Antibiotics A to Z - Antibiotics
  4. Antibiotics N-S - Antibiotics A to Z
  1. Life Science 生命科学
  2. Antibiotics 抗生素
  3. Chemical Structure Class - Antibiotics
  4. Sulfonamides - Chemical Structure Class
  1. Life Science 生命科学
  2. Antibiotics 抗生素
  3. Mechanism of Action - Antibiotics
  4. Inhibits an Enzyme - Mechanism of Action
  1. Life Science 生命科学
  2. Antibiotics 抗生素
  3. Spectrum of Activity - Antibiotics
  4. Antibacterial - Spectrum of Activity
  5. L - Z - Antibacterial

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