Sodium Barbital 巴比妥钠(第二类精神管制类药品,不能销售)

CAS 144-02-5 MFCD00036203

化学结构图

144-02-5
SMILES: CCC1(CC)C(=O)N=C([O-])NC1=O.[Na+]

化学属性

Mol. FormulaC8H12N2O3.Na
Mol. Weight207.21
Stability对湿度敏感

别名和识别编码

Chemical NameSodium Barbital
Synonym {uni_hamburg} VERONAL SODIUM SALT { Barbital Na 巴比妥 Barbital, sodium deriv. Veronal sodium Diethylbarbiturate monosodium Sodium Veronal Sodium 5,5-diethylbarbiturate BARBITAL SODIUM SALT BARBITONE SODIUM SALT Barbital soluble 5,5-DIETHYLBARBITURIC ACID SALT SODIUM SALT 巴比酮鈉 Sodium barbitone VERONAL SODIUM {Chemi 二乙基巴比妥酸钠 5,5-Diethylbarbitursäure-Natriumsalz Thyalone BARBITAL SODIUM {uni_ham Sodium malonylurea 2,4,6(1H,3H,5H)- 5,5-二乙基巴比土酸钠盐 2,4,6(1H,3H,5H)-P BARBITAL NA Nervoseton {uni Embinal BARBITONE SODIUM 5,5-Diethylbarbituric acid sodium salt Sodium diethylbarbiturate 4 5,5-diethyl-barbituricacisodiumsalt Barbitone, sodium deriv. SODIUM 5,5-DIETHYLBARBITURATE 巴比妥鈉 Barbituric acid, 5,5-diethyl-, sodium salt 2,4,6(1H,3H,5H)-Pyrimidinetrione,5,5-diethyl-,monosodiumsalt(9CI) barbital sodium (INN) S Natrinal 佛罗拿 钠盐 SODIUM BARBITAL Natriumbarbitals 5,5-DIETHYLBARBITURIC ACID SODIUM SALT SODIUM DIETHYLBARBITURATE 5,5-Diethy 5,5-Diethylbarbituric acid sodium deriv. Sodium ethylbarbital 5,5-二乙基巴比土酸 钠盐 5,5-二乙基巴比土酸 钠盐 佛罗拿 钠盐 巴比妥 巴比妥钠 Barbitone sodium DIETHYLBARBITURIC ACID SODIUM SALT 2,4,6(1H,3H,5H)-Pyrimidin Soluble barbital Barbitalnatrium Natrium-5,5-diäthylbarbiturat
MDL NumberMFCD00036203
PubChem Substance ID23681217
Beilstein Registry Number3921202
CAS Number144-02-5
EC Number205-613-9
Chemical Name Translation巴比妥钠(第二类精神管制类药品,不能销售)
Merck Number13,965
Wiswesser Line NotationT6VMVMV FHJ F2 F2 &-NA-
InChIInChI=1S/C8H12N2O3.Na/c1-3-8(4-2)5(11)9-7(13)10-6(8)12;/h3-4H2,1-2H3,(H2,9,10,11,12,13);/q;+1/p-1
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • Analytical Standards, Analytical/Chromatography, Barbiturates, Chemical Structure, Chromatography, Core Bioreagents, Drugs of Abuse, Enzyme Inhibitors, Forensic and Veterinary Standards, Research Essentials
  • {uni_hamburg} no charge; nitrogen heterocycle; alicycle; 6RingOnly; 6ring; urea; amide; lactame; 2fragments; ionic
  • {SNA} Alphabetical, BioUltra Buffers, Biological Buffers

产品应用

  • 血清蛋白电泳,肝功能测定,配制缓冲溶液,细菌培养。

相关文献及参考

  • Merck: 14,962 Beilstein: 24,IV,1904
  • Merck: 14,962
  • Short: III/20a
  • Short: III/5a
  • Short: III/10a
  • Short: IV/1b

安全信息

WGK Germany3
GHS Symbol
Hazard statements
  • H302 Harmful if swallowed 吞食有害
Hazard Codes Xn
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Signal word Warning
RTECSCQ3850000
Packing GroupIII
Hazard Class6.1(b)
UN Number 3288
Safety Statements
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
Risk Statements
  • R22 Harmful if swallowed 吞咽有害
Storage condition 密封保存。
Restrict {} 精神药品 精麻类化学品
TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 30 mg/kg/78W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Kidney, Ureter, Bladder - Kidney tumors
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 10,183,1989

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 121 gm/kg/72W-C
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Kidney, Ureter, Bladder - Kidney tumors
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 11,2149,1990

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Behavioral - general anesthetic
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 60,125,1937

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Behavioral - general anesthetic
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 60,125,1937

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 830 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   27,70,1974

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 31,1,1927

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        :

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 2400 mg/kg
SEX/DURATION            : female 8-19 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
   before birth)
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   CUSCAM Current Science.  (Current Science Assoc., Sadashivanagar P.O.,
   Bangalore 560 080, India) V.1-    1932-  Volume(issue)/page/year: 36,3,1967

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 200 mg/kg
SEX/DURATION            : female 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - other measures of fertility
REFERENCE :
   SJDBA9 Soviet Journal Developmental Biology (English Translation).
   Translation of Ontogenez. (Plenum Pub. Corp., 233 Spring St., New York, NY
   10013)  V.1-    1970-  Volume(issue)/page/year: 10,574,1979

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : In

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 690 mg/kg
SEX/DURATION            : female 1-6 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - craniofacial
   (including nose and tongue)
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 19,1309,1969

其他信息

  • 储运特性:通风低温干燥; 与库房食品原料分开存放
  • Sigma Aldrich:144-02-5(sigmaaldrich)
  • 图谱信息:巴比妥钠(144-02-5)Raman光谱 巴比妥钠(144-02-5)红外图谱(IR2) 巴比妥钠(144-02-5)核磁图( 13 CNMR) 巴比妥钠(144-02-5)红外图谱(IR1) 巴比妥钠(144-02-5)核磁图( 1 HNMR)
  • 毒性分级:中毒
  • 可燃性危险特性:可燃; 燃烧产生有毒氮氧化物和氧化钠烟雾; 长期服用对人心理有依赖性影响
  • 外观性质:白色结晶或结晶性粉末,性稳定,无气味,味苦。易溶于沸水,能溶于水,水溶液呈碱性。微溶于醇,不溶于醚和氯仿。1g溶于5ml水、2.5ml沸水、400ml乙醇,不溶于乙醚和氯仿。水溶液对石蕊与酚酞呈碱性反应。0.1mol/L水溶液的pH为9.4。有毒,半数致死量(小鼠,经口)800mg/kg。。
  • 用途一:用作色谱分析试剂,也用于医药、塑料及有机合成等工业
  • 性稳定,无气味,味苦。易溶于沸水,能溶于水,水溶液呈碱性。微溶于醇,不溶于醚和氯仿。1g溶于5ml水、2.5ml沸水、400ml乙醇,不溶于乙醚和氯仿。水溶液对石蕊与酚酞呈碱性反应。0.1mol/L水溶液的pH为9.4。有毒,半数致死量(小鼠,经口)800mg/kg。。
  • 巴比妥钠价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 69004324 巴比妥钠;二乙基巴比土酸钠;可溶性巴比通;佛罗拿钠 25g 38元 2011/08/23 69004314 巴比妥钠;二乙基巴比土酸钠;可溶性巴比通;佛罗拿钠 25g 150元
  • 爆炸物危险特性:接触过敏效应
  • 上游原料:氢氧化钠 --> 巴比妥酸
  • 急性毒性:口服-大鼠 LD50: 600 毫克/公斤; 口服-小鼠 LD50; 800 毫克/公斤
  • 类别:有毒物品
  • MOL 文件:144-02-5.mol
  • 灭火剂:干粉,泡沫,沙土,二氧化碳, 雾状水
  • 用途二:血清蛋白电泳,肝功能测定,配制缓冲溶液,细菌培养。

系列性分类


相关产品推荐