N-formyl-[U-13C-15N]-Met-Leu-Phe-OH N-甲酰-甲硫氨酰-亮氨酰-苯丙氨酸

CAS 59880-97-6 MFCD00036780

化学结构图

59880-97-6
SMILES: CC(O)=O.CC(O)=O.CC(O)=O.N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CC1C=CC=CC=1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O |&1:13,27,34,42,53,62,66,77|

化学属性

Mol. FormulaC21H31N3O5S
Mol. Weight437.56
Appearance powder
SolubilityDMF: 50 mg/mL, clear, colorless

别名和识别编码

Chemical NameN-formyl-[U-13C-15N]-Met-Leu-Phe-OH
Synonym Chemotactic peptide N-Formyl-L-methionyl-L-leucyl-L-phenylalanine fMLF fMLP (misnomer but widely used) N-FORMYL-MET-LEU-PHE N-Formyl-Met-Leu-Phe N-甲酰-L-甲硫氨酰-L-白氨酰-L苯丙氨酸
MDL NumberMFCD00036780
PubChem Substance ID24894846
Beilstein Registry Number2315783
CAS Number59880-97-6
EC Number227-781-2
Chemical Name TranslationN-甲酰-甲硫氨酰-亮氨酰-苯丙氨酸
Reaxys-RN2315783
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分类

  • {SNA} Other Peptides, Peptides and Proteins, Peptides for Cell Biology, 细胞信号转导和神经科学, 细胞生物学
  • {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, Cell Biology, Cell Signaling and Neuroscience, F, FM - FZ, Other Peptides, Peptides and Proteins, Peptides for Cell Biology
  • {SNA} Chemotactic Peptides, Immune Cell Signaling and Blood, Immune System Regulation, Immunomodulators, Immunomodulators and Antibiotics, Peptides and Proteins, Peptides for Cell Biology, 细胞信号转导和神经科学, 细胞生物学
  • Bioactive Small Molecules, Cell Biology,

相关文献及参考

  • 1. Showell, H.J., et al. J. Exp. Med. 143 , 1154, (1976)
  • 2. Homma, Y., et al. Biochem. J. 229 , 643, (1985)
  • Anton, P., et al., Mucosal subepithelial binding sites for the bacterial chemotactic peptide, formyl-methionyl-leucyl-phenylalanine (FMLP). Gut 42 , 374-379, (1998) 摘要
  • Niedel, J., et al., Receptor-mediated uptake and degradation of 125 I-chemotactic peptide by human neutrophils. J. Biol. Chem. 254 , 10700-10706, (1979) 摘要
  • Panaro, M.A., and Mitolo, Y., Cellular responses to FMLP challenging: a mini-review. Immunopharmacol. Immunotoxicol. 21 , 397-419, (1999) 摘要
  • Hagi, A., Activation of G-protein coupled fMLP or PAF receptor directly triggers glucose transporter type 1 (GLUT1) translocation in Chinese hamster ovary (CHO) cells stably expressing fMLP or PAF receptor. J. Med. Invest. 47 , 19-28, (2000) 摘要
  • Murikinati, S., et al., Activation Of Cannabinoid 2 Receptors Protects Against Cerebral Ischemia By Inhibiting Neutrophil Recruitment. FASEB J. 24 , 788-98, (2010) 摘要
  • Myers, S.A., et al., CD47 Knockout Mice Exhibit Improved Recovery From Spinal Cord Injury. Neurobiol. Aging 42 , 21-34, (2011) 摘要

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Safety Statements
  • S22 Do not breathe dust 不要吸入粉尘；
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
Storage condition -20°C保存 2-8°C <0°C

其他信息

  • Sigma Aldrich:5979-11-3(sigmaaldrich)
  • MOL 文件:5979-11-3.mol
  • color:white
  • F:3-10-23

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Peptides - Biochemicals and Reagents
  4. Dipeptides and Tripeptides - Peptides
  5. Tripeptides - Dipeptides and Tripeptides
  1. Bradykinins - Peptides for Cell Biology
  1. Other Peptides - Peptides for Cell Biology
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Alphabetic - Analytical Standards
  4. F - Alphabetic
  5. FM - FZ - F
  1. Immunomodulators - Peptides for Cell Biology
  2. Chemotactic Peptides - Immunomodulators

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