Colfosceril palmitate 1,2-二棕榈酰-sn-甘油-3-磷酰胆碱

CAS 63-89-8 MFCD00036903

化学结构图

63-89-8
SMILES: CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCCCCCC

化学属性

Mol. FormulaC40H80NO8P
Mol. Weight734.04
Melting Point229-229.5 °C

别名和识别编码

Chemical NameColfosceril palmitate
CAS Number63-89-8
Synonym DPPC {LY} DPPC {} {LY} DPPC {} {} {LY} DPPC {} {} {} {LY} DPPC {} {} {} {} {LY} DPPC {} {} {} {} {} {LY} DPPC {} {} {} {} {} {} {LY} DPPC {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {LY} DPPC {} {} {} {} {} {} {} {} {LY} DPPC {} {} {} {} {} {} {} {} {} {LY} DPPC {} {} {} {} {} {} {} {} {} {} {LY} DPPC {} {} {} {} {} {} {} {} {} {} {} {LY} DPPC {} {} {} {} {} {} {} {} {} {} {} {} {LY} DPPC {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} DPPC {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} DPPC {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} DPPC {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} DPPC {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} DPPC {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
MDL NumberMFCD00036903
PubChem Substance ID452110
EC Number200-567-6
Reaxys-RN1917966
Beilstein Registry Number1917966
Merck Number2477
Chemical Name Translation1,2-二棕榈酰-sn-甘油-3-磷酰胆碱
LabNetwork Molecule IDLN01314890
InChIInChI=1S/C40H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-39(42)46-36-38(37-48-50(44,45)47-35-34-41(3,4)5)49-40(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3/t38-/m1/s1
Canonical SMILESCCCCCCCCCCCCCCCC(O[C@H](COC(CCCCCCCCCCCCCCC)=O)COP(OCC[N+](C)(C)C)([O-])=O)=O
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分类

  • {SNA} Bioactive Small Molecule Alphabetical Index, Biochemicals and Reagents, DIG-DY, Glycerophospholipid Metabolism, Glycerophospholipids, Glycerophosphonocholines, Lipids, L
  • {SNA} Bioactive Small Molecules, Biochemicals and Reagents, Cell Signaling and Neuroscience, DIG-DY, Glycerophospholipid Metabolism, Glycerophospholipids, Glycerophosphonocholines, Lipids, Lipids in Cell Signaling, Metabolic Pathways,
  • {Che
  • {SNA} Glycerophospholipids, Glycerophosphonocholines, 代谢组学, 代谢通路, 生化试剂, 磷酸甘油酯代谢, 细胞生物学,

产品应用

  • Colfosceril Palmitate is a major phospholipid constituent and primary surface tension lowering component of natural lung surfactant. Colfosceril Palmitate is used as pulmonary surfactant and diagnosti

相关文献及参考

  • [2]. Akiko Uemura, et al. Induction of immune responses against glycosphingolipid antigens: comparison of antibody responses in mice immunized with antigen associated with liposomes prepared from various phospholipids. J Vet Med Sci. 2005 Dec;67(12):1197-201.
  • Cha, S., et al.: J. Biol. Chem., 273, 2153 (1998),
  • Pantusa, M., et al.: Biophys Chem., 114, 121 (2005),
  • Pantusa, M., et al.: Eur. Biophys. J., 37, 961 (2008),
  • [1]. Miller AD. Delivery of RNAi therapeutics: work in progress. Expert Rev Med Devices. 2013 Nov;10(6):781-811.
  • [1]. Miller AD. Delivery of RNAi therapeutics: work in progress. Expert Rev Med Devices. 2013 Nov;10(6):781-811.
  • [2]. Akiko Uemura, et al. Induction of immune responses against glycosphingolipid antigens: comparison of antibody responses in mice immunized with antigen associated with liposomes prepared from various phospholipids. J Vet Med Sci. 2005 Dec;67(12):1197-201.

安全信息

WGK Germany3
Storage condition -20°C, sealed storage, away from moisture {LY} -20°C, sealed storage, away from moisture <0°C <;0 {} {LY} -20°C, sealed storage, away from moisture {} {} {LY} -20°C, sealed storage, away from moisture {} {} {} {LY} -20°C, sealed storage, away from moisture {} {} {} {} {LY} -20°C, sealed storage, away from moisture {} {} {} {} {} {LY} -20°C, sealed storage, away from moisture {} {} {} {} {} {} {LY} -20°C, sealed storage, away from moisture {} {} {} {} {} {} {} {LY} -20°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {LY} -20°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {LY} -20°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {LY} -20°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C, sealed storage, aw
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
GHS Symbol
Precautionary statements
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。

其他信息

  • 上游原料:四丁酚醇
  • Acros Organics:L-alpha-二棕榈酰磷脂酰胆碱 L-alpha-Dipalmitoyl phosphatidylcholine, 98%(63-89-8)
  • MOL 文件:63-89-8.mol
  • 方法一:合成表面活性剂,由棕榈胆磷加十六烷基醇和泰洛沙泊(Tyloxapo1)组成。
  • 图谱信息:二棕榈酸磷脂酰胆碱(63-89-8)核磁图( 13 CNMR) 二棕榈酸磷脂酰胆碱(63-89-8)核磁图( 1 HNMR)
  • Sigma Aldrich:63-89-8(sigmaaldrich)
  • F:10-21
  • 二棕榈酸磷脂酰胆碱价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2010/06/21 240571000 二棕榈酸磷脂酰胆碱 L-alpha-Dipalmitoyl phosphatidylcholine 98% 100 MG 879元 2010/06/21 240575000 二棕榈酸磷脂酰胆碱 L-alpha-Dipalmitoyl phosphatidylcholine 98% 500 MG 2587元 2010/06/21 240570025 二棕榈酸磷脂酰胆碱 L-alpha-Dipalmitoyl phosphatidylcholine 98% 2.5 GR 11016元
  • 用途一:为天然表面活性物质,是外源性表面活性物质制剂的主要组分。用于抢救因RDS进行机械通气的出生体重700g以上的新生儿。

系列性分类


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