Fmoc-Leu-OH 芴甲氧羰基-L-亮氨酸

CAS 35661-60-0 MFCD00037133

化学结构图

35661-60-0
SMILES: CC(C)C[C@H](NC(=O)OCC1C2C=CC=CC=2C2C=CC=CC=21)C(O)=O

化学属性

Mol. FormulaC21H23NO4
Mol. Weight353
Melting Point154.0 to 157.0 deg-C
TSCANo
Density1.207

别名和识别编码

Chemical NameFmoc-Leu-OH
Synonym Fmoc-L-亮氨酸 Fmoc-Leu-OH N-(9-Fluorenylmethoxycarbonyl)-L-leucine N-(9-芴甲氧羰基)-L-亮氨酸 N-(9-芴甲氧羰基)-L-亮氨酸 Fmoc-L-亮氨酸 N-芴甲氧羰基-L-亮氨酸
MDL NumberMFCD00037133
PubChem Substance ID87570069
Beilstein Registry Number2178254
CAS Number35661-60-0
EC Number252-662-7
Reaxys-RN2178254
Chemical Name Translation芴甲氧羰基-L-亮氨酸
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分类

  • {SNA} Amino Acid Derivatives, Bioactive Small Molecules, Cell Biology, Chemical Biology, Chemical Synthesis, F, Leucine, Peptide Chemistry, Standard Fmoc Amino Acids
  • {SNA} Amino Acid Derivatives, Bioactive Small Molecules, Chemical Biology, Chemical Synthesis, F, Leucine, Peptide Chemistry, Standard Fmoc Amino Acids,
  • {SNA} Amino Acids & Derivatives, Catalysis and Inorganic Chemistry, Chemical Biology, Chemical Synthesis, Leucine, Peptide Chemistry, Standard Fmoc Amino Acids, The Yu MPAA Ligand Library

产品应用

  • PPARγ的配体，诱导胰岛素的敏感性，而不是脂肪细胞分化

相关文献及参考

  • Rocchi, S., et al., A unique PPARgamma ligand with potent insulin-sensitizing yet weak adipogenic activity. Mol. Cell. 8 , 737, (2001) 摘要

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Signal word Warning
GHS Symbol
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Storage condition 储存温度2-8°C

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Gene Regulation and Expression - Cell Signaling and Neuroscience
  5. PPAR and RXR Regulators - Gene Regulation and Expression
  1. Chemical Synthesis 化学合成
  2. Chemical Biology 生物化学
  3. Peptide Chemistry 多肽化学
  4. Amino Acid Derivatives 氨基酸及其衍生物
  5. Leucine - Amino Acid Derivatives
  1. Chemical Synthesis 化学合成
  2. Chemical Biology 生物化学
  3. Peptide Chemistry 多肽化学
  4. Amino Acid Derivatives 氨基酸及其衍生物
  5. Leucine - Amino Acid Derivatives
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Amino Acids 氨基酸
  4. Modified Amino Acids - Amino Acids
  5. Fmoc-amino Acids
  1. Life Science 生命科学
  2. Biochemistry / Glyco-Chemistry
  3. Protected & Labeled Amino Acids

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