N-(2-Bromobenzyl)-N,N-Dimethylethanaminium 4-Methylbenzenesulfonate N-(2-溴苄基)-N,N-二甲基乙胺-4-甲基苯磺酸盐

CAS 61-75-6 MFCD00038731

化学结构图

61-75-6
SMILES:

化学属性

Mol. FormulaC11H17BrN.C7H7O3S
Mol. Weight414.40

别名和识别编码

Chemical NameN-(2-Bromobenzyl)-N,N-Dimethylethanaminium 4-Methylbenzenesulfonate
CAS Number61-75-6
Synonym (2-Bromobenzyl)ethyldimethylammonium p-toluenesulfonate Benzenemethanaminium, 2-bromo-N-ethyl-N,N-dimethyl-, salt with Bretylium tosylate ######## ASL-603
MDL NumberMFCD00038731
EC Number200-516-8
Chemical Name TranslationN-(2-溴苄基)-N,N-二甲基乙胺-4-甲基苯磺酸盐
Wiswesser Line NotationER B1K2&1&1 &OSWR D1
LabNetwork Molecule IDLN00188680
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分类

  • Amines
  • Aromatics
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Sulfur & Selenium Compounds
  • {SNA} Adrenergics, Cell Biology, Cell Signaling and Neuroscience, Neuroscience, Neurotransmission, Neurotransmitters, Others

产品应用

  • Bretylium tosylate has a biphasic response, initially inducing norepinephrine release followed by sympathetic ganglionic blockade. Bretylium tosylate is a class III antiarrhythmic agent and a competit

相关文献及参考

  • Kuntzman, R., et al.: Clin. Pharmacol. Ther., 11, 829 (1970),
  • Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971),
  • Carter, J.E., et al.: Anal. Profiles Drug Subs., 9, 71 (1980),

安全信息

RTECSBO9450000
WGK Germany3
Safety Statements
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
Hazard Codes Xn
Risk Statements
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 64 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PBPSDY Pharmacological and Biochemical Properties of Drug Substances.
   (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC
   20037)  V.1-    1977-  Volume(issue)/page/year: 2,148,1979

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 43 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PBPSDY Pharmacological and Biochemical Properties of Drug Substances.
   (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC
   20037)  V.1-    1977-  Volume(issue)/page/year: 2,148,1979

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 30 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PBPSDY Pharmacological and Biochemical Properties of Drug Substances.
   (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC
   20037)  V.1-    1977-  Volume(issue)/page/year: 2,148,1979

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 160 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PBPSDY Pharmacological and Biochemical Properties of Drug Substances.
   (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC
   20037)  V.1

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Neuroscience - Cell Signaling and Neuroscience
  5. Neurotransmission - Neuroscience
  6. Neurotransmitters - Neurotransmission
  7. Adrenergics - Neurotransmitters
  8. Others - Adrenergics
  1. Functional Group 官能团索引
  2. quaternary ammonium salt

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