Halazone 哈拉宗

CAS 80-13-7 MFCD00045858

化学结构图

80-13-7
SMILES: OC(=O)C1C=CC(=CC=1)S(=O)(=O)N(Cl)Cl

化学属性

Mol. FormulaC7H5Cl2NO4S
Mol. Weight270.08
Appearance 白色结晶或结晶性粉末。约195℃分解。微溶于水和氯仿,溶于碱性溶液。有氯气味。

别名和识别编码

Chemical NameHalazone
MDL NumberMFCD00045858
CAS Number80-13-7
Synonym p-(dichlorosulfamoyl)-benzoicaci Parasulfondichloramido benzoic acid 净水龙 Cloritines p-Carboxybenzenesulfondichloroamide P-(DICHLOROSULFAMOYL)BENZOIC ACID 对(N,N-二氯胺磺酰基)苯甲酸 双氯胺酸 Pantocid p-(N,N-Dichlorosulfamyl)benzoic acid HALAZONE Benzoic acid, 4-[(dichloroamino)sulfonyl]- Halazone 4-((dichloroamino)sulfonyl)-benzoicaci 司班通 Kyselina p-N,N-dichlorsulfamoylbenzoova 4-(N,N-二氯胺磺酰基)苯甲酸 合拉宗 P-CARBOXYBENZENESULFONDICHLORAMIDE p-(Dichlorosulfamoyl)benaoicacid NSC 60717 p-Sulfondichloramidobenzoic acid Benzoic acid, 4-((dichloroamino)sulfonyl)- Halozone p-Dichlorosulfamoylbenzoic acid 4-(DICHLOROSULFAMOYL)BENZOIC ACID nsc60717 清水龙 海氯宗 4-[(dichloroamino)sulfonyl]-benzoicaci P-(N,N-DICHLOROSULFAMYL)BENZOIC ACID P-(SULFODICHLORAMIDO)BENZOIC ACID kyselinap-n,n-dichlorsulfamoylbenzoova PANTOCID 卤胺宗 Halazon 4-(N,N-Dichlorosulfamoyl)benzoic acid p-(N,N-Dichlorosulfamoyl)benzoic acid 哈拉宗
PubChem Substance ID87570764
EC Number201-253-1
Reaxys-RN2740018
Merck Number4590
Chemical Name Translation哈拉宗
Wiswesser Line NotationQVR DSWNGG
Beilstein Registry Number2740018
LabNetwork Molecule IDLN00193380
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分类

  • {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, D, DIA - DIC, 分析/色谱
  • {SNA} Alphabetic, Analytical Standards, Analytical/Chromatography, D, DIA - DIC
  • {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, D, DIA - DIC

相关文献及参考

  • [2]. Rema Iyer, et al. Inhibition Profiling of Human Carbonic Anhydrase II by High-Throughput Screening of Structurally Diverse, Biologically Active Compounds. J Biomol Screen. 2006 Oct;11(7):782-91.
  • [1]. M Rack, et al. Effects of Some Chemical Reagents on Sodium Current Inactivation in Myelinated Nerve Fibers of the Frog. Biophys J. 1986 Oct;50(4):557-64.
  • [1]. M Rack, et al. Effects of Some Chemical Reagents on Sodium Current Inactivation in Myelinated Nerve Fibers of the Frog. Biophys J. 1986 Oct;50(4):557-64.
  • [2]. Rema Iyer, et al. Inhibition Profiling of Human Carbonic Anhydrase II by High-Throughput Screening of Structurally Diverse, Biologically Active Compounds. J Biomol Screen. 2006 Oct;11(7):782-91.

安全信息

WGK Germany3
RTECSDG8050000
GHS Symbol
Signal word
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P350
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P332+P313
  • P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
Packing GroupIII
Hazard Class5.1
UN Number 1479
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals",
   11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year:
   11,723,1989

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - chronic pulmonary edema
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   PHRPA6 Public Health Reports.  (U.S. Government Printing Office, Supt. of
   Documents, Washington, DC 20402)  V.1-    1878-  Volume(issue)/page/year:
   59,541,1944

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 6666 ug/plate
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 8(Suppl
   7),1,1986

其他信息

  • MOL 文件:80-13-7.mol
  • 储运特性:库房低温, 通风, 干燥
  • 类别:农药
  • 哈拉宗价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 H0348 哈拉宗 Halazone 5G 299元
  • 毒性分级:中毒
  • MSDS 信息:4-(N,N-Dichlorosulfamoyl)benzoic acid(80-13-7).msds
  • TCI Shanghai:哈拉宗 Halazone,>;90.0%(T)(80-13-7)
  • 急性毒性:口服- 大鼠 LD50 3500 毫克/ 公斤; 静脉- 大鼠 LD50: 300 毫克/公斤
  • 方法一:由对氨磺酰苯甲酸钠经氯化而得。先将对氨磺酰苯甲酸溶解在氢氧化钠溶液中,配制成25%的对氨磺酰苯甲酸钠溶液。将此溶液放入氯化锅,再加入氢氧化钠溶液。在5℃以下通入氯气,至pH7-8时,取反应液测试终点(反应液过滤后加酸,无沉淀为终点)。至达终点后,停止通氯,搅拌15min,过滤。用水洗涤滤饼,甩干,在40℃以下干燥。粉碎、过筛得哈拉宗。收率85%。
  • 上游原料:对氨磺酰苯甲酸钠
  • Sigma Aldrich:80-13-7(sigmaaldrich)
  • 灭火剂:水, 二氧化碳, 干粉, 砂土
  • 用途一:该品为消毒防腐药,用于饮水消毒。
  • 图谱信息:哈拉宗(80-13-7)核磁图( 13 CNMR) 哈拉宗(80-13-7)红外图谱(IR2) 哈拉宗(80-13-7)质谱(MS) 哈拉宗(80-13-7)红外图谱(IR1)
  • 可燃性危险特性:可燃, 火场排出氮氧化物, 硫氧化物和氯化物辛辣刺激烟雾

系列性分类


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