DL-Epinephrine (hydrochloride) (±)-肾上腺素 盐酸盐

CAS 329-63-5 MFCD00050562

化学结构图

329-63-5
SMILES: CNCC(O)c1ccc(O)c(O)c1.Cl

化学属性

Mol. FormulaC9H13NO3· HCl
Mol. Weight219.67
SolubilitySoluble in water: >50 mg/mL.
Stability对光线敏感

别名和识别编码

Chemical NameDL-Epinephrine (hydrochloride)
Synonym DL-EPINEPHRINE HYDROCHLORIDE 4-(1-hydroxy-2-(methylamino)ethyl)-,hydrochloride,(+-)-2-benzenediol (+/-)-ADRENALIN HYDROCHLORIDE DL-ADRENALINE HYDROCHLORIDE TIMTEC-BB SBB003360 (+/-)-EPINEPHRINE HYDROCHLORIDE DL-3,4-DIHYDROXY(1-HYDROXY-2-METHYLAMINOETHYL)BENZENE HYDROCHLORIDE RACEMIC EPINEPHRINE HYDROCHLORIDE (+-)-adrenalinehydrochloride DL-3,4-DIHYDROXY-ALPHA-[(METHYLAMINO)METHYL]BENZYL ALCOHOL HYDROCHLORIDE Adrenaline Hcl, racepinephrine hcl epinephrinehydrochloride(racepinephrinehydrochloride) dl-Adrenaline hydrochloride 肾上腺素盐酸盐 4-(1-Hydroxy-2-[methylamino]ethyl)-1,2-benzenediol hydrochloride 消旋肾上腺素 (+-)-Adrenaline hydrochloride (±)-4-[1-hydroxy-2-(methylamino)ethyl]pyrocatechol hydrochloride 4-[1-hydroxy-2-(methylamino)ethyl]-,hydrochloride,(+/-)-2-benzenediol (±)-肾上腺素 盐酸盐 消旋肾上腺素 rs-epinephrine hcl (±)-Epinephrine hydrochloride benzylalcohol,3,4-dihydroxy-alpha-((methylamino)methyl)-,hydrochloride,(+-) DL-1-(3,4-DIHYDROXYPHENYL)-2-METHYLAMINOETHANOL HYDROCHLORIDE 1,2-Benzenediol, 4-(1-hydroxy-2-(methylamino)ethyl)-, hydrochloride, RAC EPINEPHRINE HCL 1,2-Benzenediol, 4-1-hydroxy-2-(methylamino)ethyl-, hydrochloride 4-[1-HYDROXY-2-(METHYLAMINO)ETHYL]-1,2-BENZENEDIOL HYDROCHLORIDE 4-(1-Hydroxy-2-(methylamino)ethyl)benzene-1,2-diol hydrochloride; DL-Adrenaline hydrochloride
MDL NumberMFCD00050562
PubChem Substance ID5924
EC Number206-346-0
CAS Number329-63-5
Chemical Name Translation(±)-肾上腺素 盐酸盐
Merck Number3619
Wiswesser Line NotationQR BQ DYQ1M1 &GH
LabNetwork Molecule IDLN00355688
InChIInChI=1S/C9H13NO3.ClH/c1-10-5-9(13)6-2-3-7(11)8(12)4-6;/h2-4,9-13H,5H2,1H3;1H
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分类

  • {SNA} Adrenergics, Adrenergics - Agonists, Agonists, Bioactive Small Molecule Alphabetical Index, E, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Neuroscience, Neurotransmission, Neurotransmitters, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 蛋白质及衍生物
  • {SNA} Adrenergics, Adrenergics - Agonists, Agonists, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, E, GPCR Modulators,

产品应用

  • An adrenergic receptor agonist.

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P301+P310
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P305+P351+P338
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H311 Toxic in contact with skin 皮肤接触中毒
  • H301 Toxic if swallowed 吞食有毒
  • H319 Causes serious eye irritation 严重刺激眼睛
RTECSDO3330000
Signal word Danger
Personal Protective Equipment Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Hazard Codes T
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R24/25 Toxic in contact with skin and if swallowed 皮肤接触及吞食都有毒
UN Number 2811 UN 2811 6.1/PG 2
Packing GroupII
Hazard Class6.1(a)
Storage condition 储存温度2-8°C
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1250 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YAKUD5 Gekkan Yakuji.  Pharmaceuticals Monthly.  (Yakugyo Jihosha, Inaoka
   Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan)  V.1-   1959-
   Volume(issue)/page/year: 24,1705,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 90 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YAKUD5 Gekkan Yakuji.  Pharmaceuticals Monthly.  (Yakugyo Jihosha, Inaoka
   Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan)  V.1-   1959-
   Volume(issue)/page/year: 24,1705,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 7800 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 92,369,1948

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 92,108,1948

TYPE OF TEST

其他信息

  • 毒性分级:剧毒
  • 急性毒性:口服-小鼠 LD50:90 毫克/公斤;腹腔-小鼠 LD50:0.78 毫克/公斤
  • (±)-Epinephrine hydrochloride is an adrenergic receptor agonist.
  • 图谱信息:肾上腺素盐酸盐(329-63-5)核磁图( 13 CNMR) 肾上腺素盐酸盐(329-63-5)红外图谱(IR2) 肾上腺素盐酸盐(329-63-5)核磁图( 1 HNMR) 肾上腺素盐酸盐(329-63-5)红外图谱(IR1)
  • MOL 文件:329-63-5.mol
  • 储运特性:库房通风低温干燥; 与食品原料分开存放
  • 灭火剂:干粉、泡沫、砂土、二氧化碳, 雾状水
  • TCI Shanghai:DL-肾上腺素盐酸盐 DL-Adrenaline Hydrochloride,>;98.0%(LC)(T)(329-63-5)
  • 可燃性危险特性:可燃; 燃烧释放有毒氮氧化物和氯化氢烟雾
  • Sigma Aldrich:329-63-5(sigmaaldrich)
  • 类别:有毒物品

系列性分类


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