(±)-DOI hydrochloride
CAS 42203-78-1 MFCD00055199
化学结构图
SMILES: Cl.COC1=CC(I)=C(C=C1CC(C)N)OC
化学属性
| Mol. Formula | C11H16INO2· HCl |
|---|---|
| Mol. Weight | 358 |
别名和识别编码
| Chemical Name | (±)-DOI hydrochloride |
|---|---|
| Synonym | (±)-1-(2,5-Dimethoxy-4-iodophenyl)-2-aminopropane hydrochloride (±)-2,5-Dimethoxy-4-iodoamphetamine hydrochloride (±)-DOI (±)-DOI (±)-1-(2,5-Dimethoxy-4-iodophenyl)-2-aminopropane hydrochloride (±)-2,5-Dimethoxy-4-iodoamphetamine hydrochloride (±)-DOI hydrochloride |
| CAS Number | 42203-78-1 |
| PubChem Substance ID | 24278092 |
| MDL Number | MFCD00055199 |
| Chemical Name Translation |
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分类
- {SNA} Agonists, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Neuroscience, Neurotransmission, Neurotransmission (Obesity), Neurotransmitters, Serotonergics, Serotonergics - Agonists, 生化试剂, 细胞信号转导和神经科学,
相关文献及参考
- Gaggi, R., et al., Effect of the selective 5-HT receptor agonists 8-OHDPAT and DOI on behavior and brain biogenic amines of rats. Gen. Pharmacol. 28 , 583-587, (1997) 摘要
- Marek, G.J., et al., LSD and the phenethylamine hallucinogen DOI are potent partial agonists at 5-HT 2A receptors on interneurons in rat piriform cortex. J. Pharmacol. Exp. Ther. 278 , 1373-1382, (1996) 摘要
- Ichikawa, J., et al., DOI, a 5-HT 2A/2C receptor agonist, potentiates amphetamine-induced dopamine release in rat striatum. Brain Res. 698 , 204-208, (1995) 摘要
安全信息
GHS Symbol
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- S22 Do not breathe dust 不要吸入粉尘；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
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