Chlorophacinone 氯鼠酮

CAS 3691-35-8 MFCD00055360

化学结构图

3691-35-8
SMILES: O=C(C(C1C=CC=CC=1)C1C=CC(Cl)=CC=1)C1C(=O)C2C=CC=CC=2C1=O

化学属性

Mol. FormulaC23H15ClO3
Mol. Weight374.83
Flash Point>100 °C
Solubility不溶于水，溶于丙酮、乙醇、乙酸乙酯。
Melting Point140°C

别名和识别编码

Chemical Name1,3-Indandione, 2-((p-chlorophenyl)phenylacetyl)-
CAS Number3691-35-8
Synonym CAID(R) 2-[(4-CHLOROPHENYL)PHENYLACETYL]-1H-INDENE-1,3(2H)-DIONE LIPHADIONE(R) chlorophacinone (ISO) CHLORPHACINON 1,3-Indandione, 2-[(p-chlorophenyl)phenylacetyl]- 1-(4-Chlorphenyl)-1-phenyl-acetyl-indan-1,3-dion 2-[(4-CHLOROPHENYL)-PHENYLACETYL]-1,3-INDANDIONE LIPHADIONE 鼠顿停 Baraage 2-((p-Chlorophenyl)phenylacetyl)-1,3-indandione LEPIT CAID 2-[(4-chlorophenyl)p ######## 可伐鼠 Orcomolebait 鼠可克 Rozol {Chembl { Ch 2(2-(4-Chlorophenyl)-2-phenylacetyl)indan-1,3-dione 1H-Indene-1,3(2H)-dione, 2-[(4-chlorophenyl)phenylacetyl]- Chlorfacinon 2-[（4-氯苯基）苯基乙酰基]-1H-茚-1,3（2H）-二酮 DRAT 2-(a-(4-Chlorphenyl)phenylacetyl)indan-1,3-dion ROZOL(R) RAVIAC Chloorfacinon Chlorophacinon (ISO) Redentin 2-((4-Chlorophenyl)phenylacetyl)-1H-indene-1,3 2-(2- 2-[2-(4-氯苯基)-2-苯基乙酰基]茚满-1,3-二酮 2-(4-氯苯基)苯基乙酰基)-1H-茚-1,3(2H)-二酮 Chlorphacinon {Chemicalb REDENTIN 2-(2-(4-Chlorphenyl-2-phenyl)acetyl)indan-1,3-dion 2-[(p-chlorophenyl)phenylacetyl]-1,3-indandione 2(2-(4-Chlor-phenyl-2-phenyl)acetyl)indan-1,3-dion 2-(2-Phenyl-2-(4-chlorophenyl)acetyl)-1,3-indandione 2-(alpha-p-Chlorophenylacetyl)ind ACTOSIN C Saviac Mur Afnor 1H-indene-1,3(2H)dione, 2-[(4-chlorophenyl)phenylacetyl]- 2(2-(4-Chloor-fenyl-2-fenyl)-acetyl)-indaan-1,3-dion Topitox ((4-Chlorphenyl)-1-phenyl
MDL NumberMFCD00055360
PubChem Substance ID24868865
Beilstein Registry Number2063081
EC Number223-003-0
Chemical Name Translation氯鼠酮
Merck Number13,2171
Wiswesser Line NotationL56 BV DV CHJ CVYR&R DG
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分类

  • Aromatics
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • {uni_hamburg} no charge; carbocycle; aromatic; alicycle; large ring; fused rings; 5ring; 6ring; 9ring; ketone; 1fragment
  • {SA} Alpha sort, Alphabetic, Analytical Standards, Analytical/Chromatography, C, CH, Chromatography, Environmental Standards, Pesticides, Pesticides & Metabolites, Rodenticides
  • {SNA} Alphabetical Index of Analytical Standards, All alphabetically sorted, Analytical Standards, Analytical/Chromatography, C, CH, Chromatography, Environmental Standards, Pesticides & Metabolites, Pesticides Standards, Rodenticides

产品应用

  • 是广谱杀鼠剂，杀灭家鼠和野鼠。用沾附法、混合法配制毒饵，或同其他杀鼠剂配用，使用浓度50mg/kg。

相关文献及参考

  • Hegdal, P., et al.: Environ. Toxicol. Chem., 7, 245 (1988),
  • Eason, C., et al.: Ecotoxicology, 11, 35 (2002),
  • Merck: 14,2152
  • Short: EINECS
  • Short: IV/8A
  • Stone, W., et al.: Environ. Contam. Tox., 70, 34 (2003),

安全信息

RTECSNK5335000
GHS Symbol
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P301+P310
  • P302+P350
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
Hazard statements
  • H372 Causes damage to organs through prolonged or repeated exposure 长期或频繁接触会损伤器官
  • H331 Toxic if inhaled 吸入中毒
  • H310 Fatal in contact with skin 皮肤接触致命
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
  • H300 Fatal if swallowed 吞食致命
WGK Germany3
Signal word Danger
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Hazard Codes T+;N,N,T+ T+,N T+;N
Safety Statements
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
Risk Statements
  • R48/24/25
  • R23 Toxic by inhalation 吸入有毒
  • R50/53
  • R27/28 Very toxic in contact with skin and if swallowed 皮肤接触及吞食都有剧毒
UN Number 2811 UN 2811
Restrict 剧毒化学品
Warnings 危化品目录(2015) 危险化学品 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 5 mg/kg
TOXIC EFFECTS :
   Vascular - other changes
REFERENCE :
   JTCTDW Journal of Toxicology, Clinical Toxicology.  (Marcel Dekker, 270
   Madison Ave., New York, NY 10016)  V.19-    1982-  Volume(issue)/page/year:
   27,79,1989

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >3 gm/m3/1H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd,
   eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year:
   A084,1983

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1060 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   25,42,1973

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - duck
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Detail

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - domestic
DOSE/DURATION           : 430 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GUCHAZ Guide to the Chemicals Used in Crop Protection.  (Information Canada,
   171 Slater St., Ottawa, Ont., Canada)  Volume(issue)/page/year: 6,112,1973

其他信息

  • 不溶于水，溶于甲苯、微溶于甲醇、丙酮、乙醇、油等。性质稳定，无腐蚀性。
  • NIST化学物质信息:Chlorophacinone(3691-35-8)
  • RTECS号:NK5335000
  • 外观性质:原药为黄色无臭结晶。
  • EPA化学物质信息:1H-Indene-1,3(2H)- dione, 2-[(4-chlorophenyl)phenylacetyl]- (3691-35-8)
  • PackingGroup:I
  • 用途:第一代抗凝血杀鼠剂，杀鼠机制类似敌鼠，对鼠毒性大，适口性好，用于防治家栖和野栖鼠类。使用时用0.5%母粉或0.25%油剂配成毒饵诱杀。如取1份0.5%母粉加到99份面粉及适量水中和成面团，制成粒状或块状毒饵，家鼠每房间放1～3堆，每堆3～5g，野鼠按50m 2 放1堆，每堆10g。注意预防误食或其他中毒事故，收集后死鼠必须深埋。
  • HazardClass:6.1(a)
  • MOL 文件:3691-35-8.mol
  • 毒害物质数据:3691-35-8(Hazardous Substances Data)
  • 生产方法:以邻苯二甲酸二甲酯为原料合成。

系列性分类

  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Chromatography - Analytical Standards
  4. Environmental Standards - Chromatography
  5. Pesticides & Metabolites - Environmental Standards
  6. Pesticides - Pesticides & Metabolites
  7. Rodenticides - Pesticides
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Alphabetic - Analytical Standards
  4. C - Alphabetic
  5. CH - C

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