25-Hydroxycholesterol 25-羟基胆甾醇

CAS 2140-46-7 MFCD00057815

化学结构图

2140-46-7
SMILES: C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@@]21C

化学属性

Mol. FormulaC27H46O2
Mol. Weight403

别名和识别编码

Chemical Name25-Hydroxycholesterol
CAS Number2140-46-7
Synonym Cholest-5-ene-3?,25-diol 5-Cholesten-3?,25-diol 25-Hydroxy-5-cholestene-3?-ol (3?)-Cholest-5-ene-3,25-diol 25-羟基胆固醇 25-羟基胆甾醇 5-胆甾烯-3β,25-二醇
MDL NumberMFCD00057815
Beilstein Registry Number3161259
Chemical Name Translation25-羟基胆甾醇
PubChem Substance ID65094
InChIInChI=1S/C27H46O2/c1-18(7-6-14-25(2,3)29)22-10-11-23-21-9-8-19-17-20(28)12-15-26(19,4)24(21)13-16-27(22,23)5/h8,18,20-24,28-29H,6-7,9-17H2,1-5H3/t18-,20+,21+,22-,23+,24+,26+,27-/m1/s1
LabNetwork Molecule IDLN01289776
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分类

  • {SNA} Anti-Proliferative Agents, Antitumor Agents, Bile Acid Metabolism, Biochemicals and Reagents, Cell Biology,
  • {S
  • {SNA} Anti-Proliferative Agents, Cholesterol and Derivatives, Sterol Lipids, 代谢组学, 代谢通路, 抗肿瘤药物, 生化试剂, 癌症研究, 细胞生物学, 胆汁酸代谢, 脂类
  • Inhibitors
  • {SNA} Anti-Proliferative Agents, Antitumor Agents, Bile Acid Metabolism, Biochemicals and Reagents, Cholesterol and Derivatives, Lipids, Metabolic Pathways, Sterol Lipids, 代谢组学, 癌症研究, 细胞生物学
  • Steroids
  • Pharmaceuticals
  • {SNA} Anti-Prol

产品应用

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相关文献及参考

  • Aupeix, K. et al.: Immunobiology, 194, 415 (1995); Moog, C. et al.: Antivir. Chem, Chemother., 9, 491 (1998); Ayala-Torres, S. et al.: Exp. Cell Res., 246, 193 (1999);
  • [1]. McDonald JG, et al. Editorial: 25-Hydroxycholesterol: a new life in immunology. J Leukoc Biol. 2010 Dec;88(6):1071-2.

安全信息

GHS Symbol
WGK Germany3
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P305+P351+P338
Hazard statements
  • H332 Harmful if inhaled 吸入有害
  • H315 Causes skin irritation 会刺激皮肤
  • H302 Harmful if swallowed 吞食有害
  • H312 Harmful in contact with skin 皮肤接触有害
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
Signal word
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
Hazard Codes Xn
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
  • R48 Danger of serious damage to health by prolonged exposure 长期接触有严重损害健康的危险
Storage condition 储存温度-20°C

系列性分类

  1. Life Science 生命科学
  2. Cancer Research
  3. Antitumor Agents - Cancer Research
  4. Anti-Proliferative Agents - Antitumor Agents
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Lipids - Biochemicals and Reagents
  4. Sterol Lipids - Lipids
  5. Cholesterol and Derivatives - Sterol Lipids
  1. Medical Research Areas
  2. Metabolism
  3. Endogenous Metabolite  (内源性代谢物)

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