N-(4-Aminobutyl)-2-Naphthalenesulfonamide Hydrochloride N-(4-氨基丁基)-2-萘磺酰胺盐酸盐
CAS 89108-46-3 MFCD00058052
化学结构图
SMILES: Cl.NCCCCNS(=O)(=O)C1C=C2C=CC=CC2=CC=1
化学属性
| Mol. Formula | C14 |
|---|---|
| Mol. Weight | 315 |
| Melting Point | 181.0 to 185.0 deg-C |
别名和识别编码
| Chemical Name | N-(4-Aminobutyl)-2-Naphthalenesulfonamide Hydrochloride |
|---|---|
| CAS Number | 89108-46-3 |
| Synonym | N-(4-Aminobutyl)-2-naphthalenesulfonamide Monohydrochloride W-12 N-(4-氨基丁基)-2-萘磺酰胺 盐酸盐 |
| MDL Number | MFCD00058052 |
| PubChem Substance ID | 125308002 |
| Reaxys-RN | 8589783 |
| Chemical Name Translation | N-(4-氨基丁基)-2-萘磺酰胺盐酸盐 |
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分类
- A, A-AM, AM to AQ, Alphabetic, Analytical Standards, Analytical/Chromatography, Bioactive Small Molecules, Calcium Antagonists, Cell Biology, Cell Signaling and Neuroscience, Chemical Structure, Chromatography, Drugs & Metabolites, Drugs of Abuse, Forensic and Veterinary Standards, Intracellular Calcium Signaling, Neat Compounds, Others
- {SNA} Alphabetical Index of Analytical Standards, A, A-AM, AM to AQ, Analytical Standards, Analytical/Chromatography, Bioactive Small Molecules, C
产品应用
- Calmodulin antagonist that binds to calmodulin and inhibits calcium-ion-calmodulin- regulated activities, including phosphodiesterase activation and myosin light chain kinase.
相关文献及参考
- Hidaka, H., et al.: Protein, Nuc. Acid and Enzyme, 26, 977 (1981)
- Hidaka, H., et al., N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamidea calmodulin antagonistinhibits cell proliferation. Proc. Natl. Acad. Sci. U. S. A. 78 , 4354, (1981) 摘要
- Tatsumi, R., et al., A Role For Calcium-calmodulin In Regulating Nitric Oxide Production During Skeletal Muscle Satellite Cell Activation. Am. J. Physiol. Cell Physiol. 296 , C922-9, (2009) 摘要
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