H-Phe(4-Cl)-OH L-4-氯苯丙氨酸

CAS 14173-39-8 MFCD00063065

化学结构图

14173-39-8
SMILES:

化学属性

Mol. FormulaClC6H4CH2CH(NH2)CO2H
Mol. Weight199.63
Melting Point263

别名和识别编码

Chemical NameH-Phe(4-Cl)-OH
Synonym L-PCPA 4-氯-L-苯基丙氨酸 4-Chloro-D-phenylalanine; 4-Chloro-3-phenyl-D-alanine
CAS Number14173-39-8
PubChem Substance ID24893091
EC Number238-023-5
Beilstein Registry Number2416150
MDL NumberMFCD00063065
Chemical Name TranslationL-4-氯苯丙氨酸
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分类

  • {SNA} Chemical Biology, Chemical Synthesis, Enzyme Inhibitors, Neuroscience, Neurotransmission, Neurotransmitter Metabolism, Peptide Chemistry, Phenylalanine Derivatives, Tryptophan Hydroxylase, Unnatural Amino Acids & Derivatives, 细胞信号转导和神经科学, 细胞生物学
  • {SNA} Bioactive Sma

相关文献及参考

  • Yoshino, T., and Yamaguchi, I., Possible involvement of 5-HT 2 receptor activation in aggravation of diet-induced acute pancreatitis in mice. J. Pharmacol. Exp. Ther. 283 , 1495, (1997) 摘要
  • Benkert, O., et al., Effect of p-chlorophenylalanine (PCPA) on pituitary hormones and testosterone in the human. Arzneimittelforschung 26 , 1369-1371, (1976) 摘要
  • Fratta W, et al., Letter: The effect of D- and L-p-chlorophenylalanine on the metabolism of 5-hydroxytryptamine in brain. J. Pharm. Pharmacol. 25 , 908-909, (1973) 摘要
  • Beil. 14 ,IV,1674
  • FT-NMR 1 (2), 1185:C / RegBook 1 (2), 1843:N / Structure Index 1 , 295:D:7

安全信息

GHS Symbol
WGK Germany3
Hazard statements
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
  • H301 Toxic if swallowed 吞食有毒
Personal Protective Equipment Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Hazard Codes T
Precautionary statements
  • P301+P310
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
Signal word
Safety Statements
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
Risk Statements
  • R25 Toxic if swallowed 吞咽有毒
  • R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
UN Number
Packing GroupIII

系列性分类

  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Halogenated Hydrocarbons 卤代烃
  5. Aryl 芳基卤代烃
  1. Chemical Synthesis 化学合成
  2. Chemical Biology 生物化学
  3. Peptide Chemistry 多肽化学
  4. Unnatural Amino Acid Derivatives 人工合成氨基酸
  5. Phenylalanine Derivatives - Unnatural Amino Acid Derivatives
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Neuroscience - Cell Signaling and Neuroscience
  5. Neurotransmission - Neuroscience
  6. Neurotransmitter Metabolism - Neurotransmission
  7. Enzyme Inhibitors - Neurotransmitter Metabolism
  8. Tryptophan Hydroxylase - Enzyme Inhibitors
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Cell Signaling and Neuroscience
  4. Neuroscience
  5. Neurotransmission
  6. Neuropeptides
  7. Angiotensin Metabolism

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