(R)-2-Aminohexanedioic acid (R)-2-氨基己二酸

CAS 7620-28-2 MFCD00063118

化学结构图

7620-28-2
SMILES: N[C@H](CCCC(=O)O)C(=O)O

化学属性

Mol. FormulaC6H11NO4
Mol. Weight161.16
Melting Point208-210°C
TSCANo
Refractive index-24 ° (C=1, 6mol/L HCl)
Density1.333
Boiling Point364°C at 760 mmHg

别名和识别编码

Chemical Name(R)-2-Aminohexanedioic acid
Synonym (R)-2-Aminohexanedioic acid {LY} (R)-2-Aminohexanedioic acid {} {LY} (R)-2-Aminohexanedioic acid {} {} {LY} (R)-2-Aminohexanedioic acid {} {} {} {LY} (R)-2-Aminohexanedioic acid {} {} {} {} {LY} (R)-2-Aminohexanedioic acid {} {} {} {} {} {LY} (R)-2-Aminohexanedioic acid {} {} {} {} {} {} {LY} (R)-2-Aminohexanedioic acid {} {} {} {} {} {} {} {LY} (R)-2-Aminohexanedioic acid {} {} {} {} {} {} {} {} {LY} (R)-2-Aminohexanedioic acid {} {} {} {} {} {} {} {} {} {LY} (R)-2-Aminohexanedioic acid {} {} {} {} {} {} {} {} {} {} {LY} (R)-2-Aminohexanedioic acid {} {} {} {} {} {} {} {} {} {} {} {LY} (R)-2-Aminohexanedioic acid {} {} {} {} {} {} {} {} {} {} {} {} {LY} (R)-2-Aminohexanedioic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} (R)-2-Aminohexanedioic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} (R)-2-Aminohexanedioic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} (R)-2-Aminohexanedioic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} (R)-2-A
Beilstein Registry Number1724347
PubChem Substance ID165627
CAS Number7620-28-2
MDL NumberMFCD00063118
Chemical Name Translation(R)-2-氨基己二酸
Reaxys-RN1724347
InChIKeyOYIFNHCXNCRBQI-SCSAIBSYSA-N
LabNetwork Molecule IDLN00237243
InChIInChI=1S/C6H11NO4/c7-4(6(10)11)2-1-3-5(8)9/h4H,1-3,7H2,(H,8,9)(H,10,11)/t4-/m1/s1
Canonical SMILESO=C(O)[C@H](N)CCCC(O)=O
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分类

  • {SNA} Enzyme Inhibitors, Glutamine Synthetase, Neuroscience, Neurotransmission, Neurotransmitter Metabolism, 细胞信号转导和神经科学, 细胞生物学
  • {SA} A - H, A-AM, Amino Acids, Bioactive Small Molecules, Bioc
  • {SNA} A-AM, Enzyme Inhibitors, Glutamine Synthetase, Neuroscience, Neurotransmission, Neurotransmitter Metabolism, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
  • {SNA} Enzyme Inhibitors, Glutamine Synthetase, Neuroscience, Neurotransmission,
  • {SNA} Enzyme In
  • {SNA} A-AM, Bioactive Small Molecule Alphabetical Index, Enzyme Inhibitors,

相关文献及参考

  • McBean, J., et al., Inhibition of the glutamate transporter and glial enzymes in rat striatum by the gliotoxin alpha aminoadipate. Br. J. Pharmacol. 113 , 536-540, (1994) 摘要
  • Hicks T.P. and Ito, K.I., The effects of D-alpha-aminoadipic acid on long-term potentiation in the hippocampus of the rat in vitro. J. Neurosci. Res. 24 , 139-150, (1996) 摘要
  • Beilstein:4(4)3070
  • Beil. 4 ,IV,3070

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
GHS Symbol
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
Precautionary statements
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。

其他信息

  • D-2-Aminoadipic acid is Glutamine synthetase inhibitor. Less potent enatiomer; gliotoxic only on mitotic astrocytes.
  • TCI Shanghai:D-2-氨基己二酸 D-2-Aminoadipic Acid,>;95.0%(GC)(T)(7620-28-2)
  • Alfa Aesar:D-2-氨基己二酸,98% D-2-Aminoadipic acid, 98%(7620-28-2)
  • 用途一:广泛应用于生化、医药领域
  • D-2-氨基己二酸价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 A2153 D-2-氨基己二酸 D-2-Aminoadipic Acid 5G 3880元 2014/06/02 A2153 D-2-氨基己二酸 D-2-Aminoadipic Acid 1G 1160元 2010/05/25 H27345 D-2-氨基己二酸,98% D-2-Aminoadipic acid, 98% 250mg 1102元
  • Sigma Aldrich:7620-28-2(sigmaaldrich)
  • MOL 文件:7620-28-2.mol
  • 比旋光度:-24 ° (c=1, 6N HCl)

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Neuroscience - Cell Signaling and Neuroscience
  5. Neurotransmission - Neuroscience
  6. Neurotransmitter Metabolism - Neurotransmission
  7. Enzyme Inhibitors - Neurotransmitter Metabolism
  8. Glutamine Synthetase - Enzyme Inhibitors

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