5-((2-Methylpiperazin-1-Yl)Sulfonyl)Isoquinoline 5-((2-甲基哌嗪-1-基)磺酰基)异喹啉

CAS 84477-87-2 MFCD00063403

化学结构图

84477-87-2
SMILES: CC1CNCCN1S(=O)(=O)C1=CC=CC2=CN=CC=C21

化学属性

Mol. FormulaC14H17N3O2S
Mol. Weight291.37

别名和识别编码

Chemical Name5-((2-Methylpiperazin-1-Yl)Sulfonyl)Isoquinoline
Synonym 1-(5-Isoquinolinesulfonyl)-2-methylpiperazine 1-(5-Isoquinolinesulfonyl)-2-methylpiperazine Isoquinoline-5-sulfonic 2-methyl-1-piperazide 1-(5-Isoquinolinylsulfonyl)-2-methylpiperazine H 7 H-7 Isoquinoline-5-sulfonic 2-methyl-1-piperazide
MDL NumberMFCD00063403
PubChem Substance ID24896097
Beilstein Registry Number5482740
CAS Number84477-87-2
Chemical Name Translation5-((2-甲基哌嗪-1-基)磺酰基)异喹啉
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分类

  • Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, H, Kinase/Phosphatase Biology, P to Q, Protein Kinase Inhibitors, Protein kinase A, Protein kinase A and protein kinase C (PKA and PKC), Serine/Threonine Kinase Biology, Serine/Threonine Kinase Inhibitors
  • {SNA} Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, H, Kinase/Phosphatase

相关文献及参考

  • Qiu, L.B., et al., The Role Of Protein Kinase C In The Opening Of Blood-brain Barrier Induced By Electromagnetic Pulse. Toxicology 273 , 29-34, (2010) 摘要
  • Hidaka, H., et al. Biochemistry 23 , 5036, (1984) 摘要

安全信息

WGK Germany3
RTECSTL9305000
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 94 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJCTEA European Journal of Cancer Part A.  (Pergamon Press, c/o Elsevier
   Science, 660 White Plains Rd., Tarrytown, NY 10591)  V.28A(4/5)-    1992-
   Volume(issue)/page/year: 30A,525,1994

系列性分类


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