• 原料直供
• 试剂商城
• 直接询价

分类

• {SNA} Activity, Activity Other, Enzyme Substrates, 代谢组学, 代谢通路, 生化试剂, 磷酸甘油酯代谢, 细胞生物学, 酶、抑制剂和底物
• Activity, Activity Other, Biochemicals and Reagents, Enzyme Substrates, Enzymes, Inhibitors, and Substrates, Glycerophospholipid Metabolism, Metabolic Pathways, Metabolomics
• {SNA} Activity, Activity Other, Biochemicals and Reagents, Enzyme Substrates, Enzymes, Inhibitors, and Substrates, Glycerophospholipid Metabolism, Metabolic Pathways, Metabolomics

产品应用

• sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a phospholipid; precursor in choline biosynthesis. sn-Glycero-3-phosphocholine is an intermediate in catabolic pathway of phosphatidylcholine. sn-G

相关文献及参考

• [2]. Traini E, et al. Choline alphoscerate (alpha-glyceryl-phosphoryl-choline) an old choline- containing phospholipidwith a still interesting profile as cognition enhancing agent. Curr Alzheimer Res. 2013 Dec;10(10):1070-9.
• [3]. Lee SH, et al. Late treatment with choline alfoscerate (l-alpha glycerylphosphorylcholine, α-GPC) increases hippocampal neurogenesis and provides protection against seizure-induced neuronal death and cognitive impairment. Brain Res. 2017 Jan 1;1654(Pt A):66-76.
• Aleppo, G., et al., Chronic L-alpha-glyceryl-phosphoryl-choline increases inositol phosphate formation in brain slices and neuronal cultures. Pharmacol. Toxicol. 74 , 95, (1994) 摘要
• Frattola, L., et al.: Curr. Ther. Res., 49, 683 (1991),
• Olson, D., et al.: Science, 270, 1967 (1995),
• Schmidt, G., et al.: J. Biol. Chem., 161, 523 (1945),
• [1]. Traini E, et al. Choline alphoscerate (alpha-glyceryl-phosphoryl-choline) an old choline- containing phosphol

安全信息

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >650 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JKXXAF Japanese Kokai Tokyo Koho Patents.  (U.S. Patent and Trademark
   Office, Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year:
   #93-32553

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >13 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JKXXAF Japanese Kokai Tokyo Koho Patents.  (U.S. Patent and Trademark
   Office, Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year:
   #93-32553