L-Leucine-p-nitroanilide l-亮氨酸-4-硝基苯胺

CAS 4178-93-2 MFCD00063681

化学结构图

4178-93-2
SMILES: CC(C)C[C@H](N)C(=O)Nc1ccc([N+](=O)[O-])cc1

化学属性

Mol. FormulaC12H17N3O3
Mol. Weight251.28
Melting Point88-90 °C
TSCAYes
Density1.422
SolubilitySoluble in DMSO (>100 mM), and methanol (>25 mM).
Boiling Point394.44 °C at 760 mmHg

别名和识别编码

Chemical NameL-Leucine-p-nitroanilide
Synonym L-Leucyl-4-nitroanilide {LY} L-Leucyl-4-nitroanilide {} {LY} L-Leucyl-4-nitroanilide {} {} {LY} L-Leucyl-4-nitroanilide {} {} {} {LY} L-Leucyl-4-nitroanilide {} {} {} {} {LY} L-Leucyl-4-nitroanilide {} {} {} {} {} {LY} L-Leucyl-4-nitroanilide {} {} {} {} {} {} {LY} L-Leucyl-4-nitroanilide {} {} {} {} {} {} {} {LY} L-Leucyl-4-nitroanilide {} {} {} {} {} {} {} {} {LY} L-Leucyl-4-nitroanilide {} {} {} {} {} {} {} {} {} {LY} L-Leucyl-4-nitroanilide {} {} {} {} {} {} {} {} {} {} {LY} L-Leucyl-4-nitroanilide {} {} {} {} {} {} {} {} {} {} {} {LY} L-Leucyl-4-nitroanilide {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Leucyl-4-nitroanilide {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Leucyl-4-nitroanilide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Leucyl-4-nitroanilide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Leucyl-4-nitroanilide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Leucyl-4-nitroanilide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
MDL NumberMFCD00063681
PubChem Substance ID2733285
Beilstein Registry Number2218433
CAS Number4178-93-2
EC Number224-047-3
Chemical Name Translationl-亮氨酸-4-硝基苯胺
InChIKeyGIEQEPUANFBFEJ-UHFFFAOYSA-N
LabNetwork Molecule IDLN00243202
InChIInChI=1S/C12H17N3O3/c1-8(2)7-11(13)12(16)14-9-3-5-10(6-4-9)15(17)18/h3-6,8,11H,7,13H2,1-2H3,(H,14,16)/t11-/m0/s1
Canonical SMILESN[C@@H](CC(C)C)C(NC1=CC=C([N+]([O-])=O)C=C1)=O
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分类

  • {SNA} Biochemicals and Reagents, Cell Signaling and Neuroscience, Enzyme Substrates, Enzymes, Inhibitors, and Substrates, Leucine Aminopeptidase, Leucine aminopeptidase, Peptides and Proteins, Peptides for Cell Biology, Protease Substrates, Substrates by Enzyme, 细胞生物学
  • {SA} Aminopeptidase M, Biochemicals and Reagents, Enzyme Substrates, Enzymes, Inhibitors, and Substrates, Substrates by Enzyme
  • {SNA} Enzyme Substrates, Leucine Aminopeptidase, Leucine aminopeptidase, Peptides and Proteins, Peptides for Cell Biology, Protease Substrates, Substrates by Enzyme, 生化试剂, 细胞信号转导和

产品应用

  • 光谱测定亮氨酸氨基肽酶(aminopeptidase)的发光底物，比如来自于气单胞菌(Aeromonas）嗜热脂肪芽孢杆菌(Bacillus stearothermophilus）、猪肾脏和酵母中的氨基肽酶。

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352
  • P305+P351+P338
  • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
  • P333+P313
  • P337+P313
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
  • H319 Causes serious eye irritation 严重刺激眼睛
Hazard Codes Xi
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Signal word Warning
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
Risk Statements
  • R36 Irritating to eyes 刺激眼睛
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}

其他信息

  • L-亮氨酸-4-硝基苯胺价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2010/05/25 A11994 L-亮氨酸-4-硝基苯胺, 99% L-Leucine-4-nitroanilide, 99% 5g 1624元 2010/05/25 A11994 L-亮氨酸-4-硝基苯胺, 99% L-Leucine-4-nitroanilide, 99% 1g 371元
  • Leu-pNA, Chromogenic Substrate is a substrate for aminopeptidase, a zinc dependent enzyme that assists in the digestion of proteins. The compound has been used in an ELISA assay to detect biological functionality of chicken aminopeptidase produced by E. coli. The compound has also been used to characterize the native IRAP (placental leucine aminopeptidase). Leu-pNA, Chromogenic Substrate is documented for use with pure samples as well as cell extracts in vitro. Leu-pNA, Chromogenic Substrate is a substrate of CD13.
  • Alfa Aesar:L-亮氨酸-4-硝基苯胺,99% L-Leucine-4-nitroanilide, 99%(4178-93-2)
  • F:10-23
  • MOL 文件:4178-93-2.mol
  • 用途一:光谱测定亮氨酸氨基肽酶(aminopeptidase)的发光底物，比如来自于气单胞菌(Aeromonas）嗜热脂肪芽孢杆菌(Bacillus stearothermophilus）、猪肾脏和酵母中的氨基肽酶。
  • Sigma Aldrich:4178-93-2(sigmaaldrich)

系列性分类

  1. Enzyme Substrates - Peptides for Cell Biology
  2. Protease Substrates - Enzyme Substrates
  3. Leucine aminopeptidase - Protease Substrates
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Substrates - Enzymes, Inhibitors, and Substrates
  5. Substrates by Enzyme - Enzyme Substrates
  6. Leucine Aminopeptidase - Substrates by Enzyme
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Substrates - Enzymes, Inhibitors, and Substrates
  5. Substrates by Enzyme - Enzyme Substrates
  6. Leucine Aminopeptidase - Substrates by Enzyme
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Substrates - Enzymes, Inhibitors, and Substrates
  5. Substrates by Enzyme - Enzyme Substrates
  6. Aminopeptidase M - Substrates by Enzyme
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Amino Acids 氨基酸
  4. Modified Amino Acids - Amino Acids
  5. Amides of Amino Acids

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