L-Norleucine L-正亮氨酸

CAS 327-57-1 MFCD00064423

化学结构图

327-57-1
SMILES: CCCC[C@H](N)C(=O)O

化学属性

Mol. FormulaC6H13NO2
Mol. Weight131.17
Melting Point>300°C
TSCAYes
Density1.038
Solubility1.6 G/100 ML (23 ºC)
Flash Point275 °C
Refractive index23 ° (C=5, 5mol/L HCl)
Boiling Point234.0±23.0 °C at 760 mmHg

别名和识别编码

Chemical NameL-Norleucine
CAS Number327-57-1
Synonym L-Norleucine {LY} L-Norleucine {} {LY} L-Norleucine {} {} {LY} L-Norleucine {} {} {} {LY} L-Norleucine {} {} {} {} {LY} L-Norleucine {} {} {} {} {} {LY} L-Norleucine {} {} {} {} {} {} {LY} L-Norleucine {} {} {} {} {} {} {} {LY} L-Norleucine {} {} {} {} {} {} {} {} {LY} L-Norleucine {} {} {} {} {} {} {} {} {} {LY} L-Norleucine {} {} {} {} {} {} {} {} {} {} {LY} L-Norleucine {} {} {} {} {} {} {} {} {} {} {} {LY} L-Norleucine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Norleucine {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Norleucine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Norleucine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Norleucine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Norleucine {} {} {} {} {} {} {} {} {} {} {}
PubChem Substance ID21236
EC Number206-321-4
Beilstein Registry Number4,432
MDL NumberMFCD00064423
Reaxys-RN1721750
Merck Number6706
Chemical Name TranslationL-正亮氨酸
Wiswesser Line NotationZY4&VQ
LabNetwork Molecule IDLN00238150
InChIInChI=1S/C6H13NO2/c1-2-3-4-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)/t5-/m0/s1
Canonical SMILESN[C@@H](CCCC)C(O)=O
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分类

  • {SNA} Amino Acids, Biochemicals and Reagents, Cell Biology, Chemical Biology, Chemical Synthesis, I - Z, Modified Amino Acids, Norleucine Derivatives, Nutrition Research, Peptide Chemistry, Phytochemicals by Plant (Food/Spice/Herb), Plantago ovata, Unnatural Amino Acid Derivatives
  • Amino Acid Analysis, Amino Acid Standards, Amino Acids, Peptides and Proteins, Analytical Standards, Analytical/Chromatography, Biochemicals and Reagents, Chromatography, Life Sciences Standards, Peptide Analysis and Characterization, Peptides, Standards for Amino Acid Analysis
  • {SNA} Amino Acid Analysis,
  • {SNA} Amino Aci

产品应用

  • A non-essential amino acid. Used as internal standard in amino acid analysis.

相关文献及参考

  • [2]. He T, et al. The homeostasis-maintaining metabolites from bacterial stress response to bacteriophage infection suppress tumor metastasis. Oncogene. 2018 Jun 20.
  • Internal standard for amino acid analysis: Anal. Biochem., 150, 174 (1985).
  • Merck: 14,6706
  • Merck: 14,6706 Beilstein:4,432
  • Robertson, D., et al.: Toxicol. Sci., 85 (2005),
  • Short: EINECS
  • Short: IV/8A
  • [1]. Schott KJ, et al. On the role of branched-chain amino acids in protein turnover of skeletal muscle. Studies in vivo with L-norleucine. Z Naturforsch C. 1985 May-Jun;40(5-6):427-37.
  • [1]. Schott KJ, et al. On the role of branched-chain amino acids in protein turnover of skeletal muscle. Studies in vivo with L-norleucine. Z Naturforsch C. 1985 May-Jun;40(5-6):427-37.
  • [2]. He T, et al. The homeostasis-maintaining metabolites from bacterial stress response to bacteriophage infection suppress tumor metastasis. Oncogene. 2018 Jun 20.

安全信息

GHS Symbol
WGK Germany3
Hazard statements
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes Xi
RTECSRC6308000
Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Signal word Warning
Safety Statements
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
  • S22 Do not breathe dust 不要吸入粉尘；
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
Risk Statements
  • R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Storage condition 2-8°C {LY} 2-8°C Store at RT. Store at room temperature {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { 
TYPE OF TEST            : Gene conversion and mitotic recombination
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 300 mg/L
REFERENCE :
   JGMIAN Journal of General Microbiology.  (Soc. for General Microbiology,
   Journal Sales, 62 London Rd., Reading, RG1 5AS, UK)  V.1-    1947-
   Volume(issue)/page/year: 8,45,1953

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Microorganism - not otherwise specified
DOSE/DURATION           : 100 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 12,349,1971

其他信息

  • Alfa Aesar:L-(+)-己氨酸,99% L-(+)-Norleucine, 99%(327-57-1)
  • 储运特性:库房通风低温干燥
  • MSDS 信息:alpha-Aminocaproic acid(327-57-1).msds
  • MOL 文件:327-57-1.mol
  • TCI Shanghai:L-正亮氨酸 L-Norleucine,>;99.0%(T)(327-57-1)
  • 比旋光度:22 ° (c=2, 6N HCl)
  • Acros Organics:L(+)-正亮氨酸 L(+)-Norleucine, 99+%(327-57-1)
  • 图谱信息:L-2-氨基己酸(327-57-1)质谱(MS) L-2-氨基己酸(327-57-1)红外图谱(IR2) L-2-氨基己酸(327-57-1)红外图谱(IR1)
  • 灭火剂:水, 二氧化碳, 干粉, 砂土
  • 海关编码:29224995
  • 类别:有毒物质
  • 升华点:275 °C
  • L-2-氨基己酸价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 xp620022 L-正亮氨酸;L-正白氨酸; L-原亮氨酸; L-原闪白氨基酸; L-2-氨基正己酸 1g/瓶 33.6元 2011/04/16 N0303 L-正亮氨酸 L-Norleucine 100MG 140元 2011/04/16 N0303 L-正亮氨酸 L-Norleucine 1G 458元
  • 可燃性危险特性:可燃;燃烧产生有毒氮氧化物烟雾
  • Sigma Aldrich:327-57-1(sigmaaldrich)

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Amino Acids 氨基酸
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Chromatography - Analytical Standards
  4. Life Sciences Standards - Chromatography
  5. Amino Acids, Peptides and Proteins - Life Sciences Standards
  6. Amino Acid Standards - Amino Acids, Peptides and Proteins
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Chromatography - Analytical Standards
  4. Life Sciences Standards - Chromatography
  5. Amino Acids, Peptides and Proteins - Life Sciences Standards
  6. Amino Acid Standards - Amino Acids, Peptides and Proteins
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Peptides - Biochemicals and Reagents
  4. Peptide Analysis and Characterization - Peptides
  5. Amino Acid Analysis - Peptide Analysis and Characterization
  6. Standards for Amino Acid Analysis - Amino Acid Analysis
  1. Chemical Synthesis 化学合成
  2. Chemical Biology 生物化学
  3. Peptide Chemistry 多肽化学
  4. Unnatural Amino Acid Derivatives 人工合成氨基酸
  5. Norleucine Derivatives - Unnatural Amino Acid Derivatives
  1. Chemical Synthesis 化学合成
  2. Chemical Biology 生物化学
  3. Peptide Chemistry 多肽化学
  4. Unnatural Amino Acid Derivatives 人工合成氨基酸
  5. Norleucine Derivatives - Unnatural Amino Acid Derivatives
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Albumins and Transport Proteins
  4. Albumin
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Amino Acids
  4. Amino Acids
  1. Medical Research Areas
  2. Metabolism
  3. Endogenous Metabolite  (内源性代谢物)

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