5H-Cyclopropa(3,4)benz(1,2-e)azulen-5-one,1,1a-alpha,1b-beta,4,4a,7a-alpha,7b,8,9,9a-decahydro-4a-alpha,7b-alpha,9-beta,9a-alpha-tetrahydroxy-3-hydroxymethyl-1 ,1,6,8-alpha- tetramethyl-,9,9a-didecanoate

CAS 24928-17-4 MFCD00065449

化学结构图

24928-17-4
SMILES: CC1(C)[C@H]2[C@@H]3C=C(C[C@@]4(O)[C@@H](C=C(C)C4=O)[C@@]3(O)[C@H](C)[C@@H](OC(=O)CCCCCCCCC)[C@@]12OC(=O)CCCCCCCCC)CO

化学属性

Mol. FormulaC40H64O8
Mol. Weight672.93

别名和识别编码

Chemical NamePhorbol 12,13-didecanoate
Synonym 4β-Phorbol 12,13-didecanoate 4β-Phorbol didecanoate 5H-Cyclopropa[3,4]benz[1,2-e]azulen-5-one, 1,1aα,1bβ,4,4a,7aα,7b,8,9,9a-decahydro-4aβ,7bα,9β,9aα-tetrahydroxy-3-(hydroxymethyl)-1,1,6,8a-tetramethyl-, 9,9a-didecanoate, (+)- Decanoic acid, (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-9aH-cyclopropa[3,4]benz[1,2-e]azulene-9,9a-diyl ester Decanoic acid, 1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-9aH-cyclopropa[3,4]benz[1,2-e]azulene-9,9a-diyl ester, [1aR-(1aα,1bβ,4aβ,7aα,7b. α.,8α,9β,9aα)]- Decanoic acid, 9,9a-diester with 1,1aα,1bβ,4,4a,7aα,7b,8, 9,9a-decahydro-4aβ,7bα,9β,9aα-tetrahydroxy-3-(hydroxymethyl)-1,1,6,8α-tetramethyl-5H-cyclopropa[3,4]benz[1,2-e]azulen-5-one, (+)- PDD PDD Phorbol 12,13-dicaprinate PdD Phorbol 12,13-dicaprinate Phorbol 12,13-didecanoate Phorbol dicaprate Phorbol-12,13-didecanoate {} {uni_hamburg}
MDL NumberMFCD00065449
PubChem Substance ID24899003
Beilstein Registry Number6036113
CAS Number24928-17-4
Chemical Name Translation
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {uni_hamburg}
  • {SNA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Kinase/Phosphatase Biology, P, Protein Kinase Activators, Protein Kinase C (PKC), Serine/Threonine Kinase Activators, Serine/Threonine Kinase Biology

相关文献及参考

  • Short: III/13a Title: Metals: Phonon States, Electron States and Fermi Surfaces: Phonon States of Elements. Electron States and Fermi Surfaces of Alloys Author: Dederichs, P.H.; Schober, H.; Sellmyer, D.J. Editor: Hellwege, K.-H.; Olsen, J.L. Source: Landolt-Börnstein, New Series Volume: III/13a Year: 1981 ISBN: 3-540-09774-0 ISBN: 978-3-540-09774-7 Internet Resource: DOI:10.1007/b19988 RefComment: 904 figs., X, 458 pages. Hardcover Abstract: Volume III/13 covers data on phonon and electron states and Fermi surfaces of metals. Both experimental and theoretical results published up to 1980 are included. Metallic elements and compounds, disordered alloys as well as homogeneously strained metallic elements are con-sidered. An appendix presents a compilation of all Bravias lattices, primitive unit cells, reciprocal lattices, and first Brillouin zones.
  • Short: III/21c Title: Superconductors: Transition Temperatures and Characterization Of Elements, Alloys and Compounds: O (without cuprates) ... Sc Author: Flükiger, R.; Hulliger, F.; Kaner, N.; Luo, H.L.; Müller, R.; Radhakrishnan, T.S.; Shelton, R.N.; Weis, F.; Wolf, T.; Yu, D. Editor: Flükiger, R.; Klose, W. Source: Landolt-Börnstein, New Series Volume: III/21c Year: 1997 ISBN: 3-540-56047-5 ISBN: 978-3-540-56047-0 Internet Resource: DOI:10.1007/b42902 RefComment: XXVIII, 317 pages. Hardcover Abstract: In volume III/21 an attempt is made to compile the reported data on superconducting materi-als, from the discovery of this phenomenon to the present day. The data comprise various modifications of a material, e.g. bulk state, thin films,implanted films, filamentary wires and others. Where available,data obtained under high pressure or after high energy particle irradia-tion are also tabulated. The goal of this volume is to establish a complete and reliable compilation of critically reviewed experimental data, excluding pure theoretical work. A particular effort was made to present not only su

安全信息

RTECSGZ0653000
WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5472 ug/kg/6W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   31,1074,1971

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 318 mg/kg/12W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
   Tumorigenic - tumors at site of application
REFERENCE :
   PLMEAA Planta Medica.  (Georg Thieme Verlag, Postfach 732, D-7000 Stuttgart
   1, Fed. Rep. Ger.) V.1-    1953-  Volume(issue)/page/year: 22,241,1972

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 17 mg/kg/16W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
REFERENCE :
   CCSUDL Carcinogenesis--A Comprehensive Survey.  (Raven Press, 1185 Ave. of
   the Americas, New York, NY 10036)  V.1-    1976-  Volume(issue)/page/year:
   2,11,1978

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 1 mg/L
REFERENCE :
   NATUAS Nature.  (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736)
   V.1-    1869-  Volume(issue)/page/year: 294,263,1981

TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Rodent - rat Liver
DOSE/DURATION           : 10 ug/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   40,4541,1980

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 200 ug/tube
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   33,3103,1973

TYPE OF TEST            : Morphological transformation
TEST SYSTEM             : Rodent - hamster Embryo
DOSE/DURATION           : 100 ug/L
REFERENCE :
   CALEDQ Cancer Letters (Shannon, Ireland).  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1975- Volume(issue)/page/year:
   17,1,1982

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