Ritanserin 利坦丝林
CAS 87051-43-2 MFCD00069341
化学结构图
SMILES: CC1N=C2SC=CN2C(=O)C=1CCN1CCC(CC1)=C(C1C=CC(F)=CC=1)C1C=CC(F)=CC=1
化学属性
| Mol. Formula | C27H25F2N3OS |
|---|---|
| Mol. Weight | 477.57 |
别名和识别编码
| Chemical Name | Ritanserin |
|---|---|
| CAS Number | 87051-43-2 |
| Synonym | 6-[2-[4-(bis(4-Fluorophenyl)methylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one 6-[2-[4-[Bis(4-fluorophenyl)methylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one Ritanserin Tiserton |
| MDL Number | MFCD00069341 |
| PubChem Substance ID | 24278117 |
| Chemical Name Translation | 利坦丝林 |
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信息真实价格透明
资金保障
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分类
- {SNA} Antagonists,
- Sulfur & Selenium Compounds
- Heterocycles
- {SNA} Antagonists, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Neuroscience, Neurotransmission, Neurotransmitters, Proteins and Derivatives, R, Serotonergics, Serotonergics - Antagonists
- Pharmaceuticals
- Intermediates & Fine Chemicals
- {SNA} Antagonists, Bioactive Small Molecule Alphabetical Index, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Neuroscience, Neurotransmission, Neurotransmitters,
- Aromatics
产品应用
- A potent 5-HT2A serotonin receptor antagonist/inverse agonist that crosses the blood-brain barrier.
相关文献及参考
- Krajl, M., et al.: Biochem. Pharmacol., 14, 1684 (1965),
- Miorelli, S., et al.: Mutagenesis, 23, 93 (2008),
- Yura, A., et al.: Brain Res., 738, 96 (1996),
- [1]. Leysen JE, et al. Receptor-binding properties in vitro and in vivo of ritanserin: A very potent and long acting serotonin-S2 antagonist. Mol Pharmacol. 1985 Jun;27(6):600-11.
安全信息
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- S22 Do not breathe dust 不要吸入粉尘；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
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