2-Amino-6-chloropurine 2-氨基-6-氯嘌呤

CAS 10310-21-1 MFCD00075252

化学结构图

10310-21-1
SMILES: Nc1nc(Cl)c2nc[nH]c2n1

化学属性

Mol. FormulaC5H4ClN5
Mol. Weight170
Melting Point>300
TSCANo
Density2.09
Solubility1.7 G/L (20 ºC)
Appearance 白色或淡黄色粉末。

别名和识别编码

Chemical Name2-Amino-6-chloropurine
CAS Number10310-21-1
Alfabeta NameAMINOCHLOROPURINE 26---
MDL NumberMFCD00075252
Synonym 6-Chloro-7H-purin-2-ylamine; 6-Chloroguanine 6-CHLOROGUANINE extrapure 2-Amino-6-Chloropurine(6-Chloroguanine) 9H-PURIN-2-AMINE, 6-CHLORO- 2-AMINO-4-CHLOROPYRROLO[2,3-D]PYRIMIDINE 2-Amino-6-chloro-9H-purine 99% 2-Amino-6-chloro-9H-purine 6-CHLOROGUANINE CRYSTALLINE 2-AMINO-6-CHLOROPURINE 6-chloro-1h-purin-2-amine 1H-Purin-2-amine, 6-chloro- 6-CHLORO-2-AMINOPURINE
Beilstein Registry Number9626
EC Number233-686-7
PubChem Substance ID87562862
Chemical Name Translation2-氨基-6-氯嘌呤
Reaxys-RN610965
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分类

  • Bases & Related Reagents
  • Nucleotides
  • Heterocycles
  • Amines
  • Aromatics
  • {SNA} Building Blocks, Chemical Synthesis, Halogenated Heterocycles, Heterocyclic Building Blocks, Purines

相关文献及参考

  • Beilstein:26(5)16,97

安全信息

Warnings IRRITANT, KEEP COLD
RTECSUO7502000
WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Signal word Warning
GHS Symbol
Safety Statements
  • S22 Do not breathe dust 不要吸入粉尘；
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
Hazard Codes Xi
Storage condition Keep Cold 
TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 20 mg/L/24H
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 139,149,1984

其他信息

  • 用途一:用作阿昔洛韦中间体
  • 检测方法:HPLC,NMR
  • Hazard Note:Irritant/Keep Cold
  • MOL 文件:10310-21-1.mol
  • 2-氨基-6-氯嘌呤价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/04/16 A1407 2-氨基-6-氯嘌呤 2-Amino-6-chloropurine 5G 1970元 2011/04/16 A1407 2-氨基-6-氯嘌呤 2-Amino-6-chloropurine 1G 596元 2010/06/21 149290050 2-氨基-6-氯嘌呤 2-Amino-6-chloropurine 99+% 5 GR 2516元
  • 用途二:抗病毒剂泛昔洛韦和泮昔洛韦的中间体。
  • Acros Organics:2-氨基-6-氯嘌呤 2-Amino-6-chloropurine, 99+%(10310-21-1)
  • TCI Shanghai:2-氨基-6-氯嘌呤 2-Amino-6-chloropurine,>;98.0%(T)(10310-21-1)
  • MSDS 信息:6-Chloroguanine(10310-21-1).msds
  • 上游原料:鸟嘌呤 --> 2,4,5-三氨基-6-氯嘧啶
  • F:10
  • Alfa Aesar:2-氨基-6-氯嘌呤,99% 2-Amino-6-chloropurine, 99%(10310-21-1)
  • 图谱信息:2-氨基-6-氯嘌呤(10310-21-1)红外图谱(IR1) 2-氨基-6-氯嘌呤(10310-21-1)质谱(MS) 2-氨基-6-氯嘌呤(10310-21-1)红外图谱(IR2)
  • Sigma Aldrich:10310-21-1(sigmaaldrich)
  • 下游产品:6-硫鸟嘌呤 --> O-6-苄基鸟嘌呤 --> 更昔洛韦 --> 泛昔洛韦 --> 2-氨基-6-碘嘌呤 --> 9-[4-羟基-3-(羟甲基)-丁基]-鸟嘌呤
  • 方法一:可用2,9-二酰基鸟嘌呤或2,4,5-三氨基-6-氯嘧啶制取。

系列性分类

  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Piperidones 哌啶酮
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Purines 嘌呤
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Proteins and Derivatives - Biochemicals and Reagents
  4. Plasma & Blood Proteins - Proteins and Derivatives
  5. Plasma, Blood, and Related Proteins and Reagents - Plasma & Blood Proteins
  6. Bilirubin - Plasma, Blood, and Related Proteins and Reagents
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Halogenated Heterocycles 卤代杂环
  5. Purines - Halogenated Heterocycles
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Halogenated Heterocycles 卤代杂环
  5. Piperidines

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