4-(3-Butoxy-4-Methoxybenzyl)Imidazolidin-2-One 4-(3-丁氧基-4-甲氧基苯基)咪唑啶-2-酮

CAS 29925-17-5 MFCD00077397

化学结构图

29925-17-5
SMILES: COC1C=CC(CC2CNC(=O)N2)=CC=1OCCCC

化学属性

Mol. FormulaC15H22N2O3
Mol. Weight278.35

别名和识别编码

Chemical Name4-(3-Butoxy-4-Methoxybenzyl)Imidazolidin-2-One
Synonym 4-(3-Butoxy-4-methoxybenzyl)imidazolidin-2-one Ro 20-1724
MDL NumberMFCD00077397
PubChem Substance ID24278195
CAS Number29925-17-5
Chemical Name Translation4-(3-丁氧基-4-甲氧基苯基)咪唑啶-2-酮
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分类

  • {SA} B, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Cyclic Nucleotide Metabolism, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, G Proteins and Cyclic Nucleotides,
  • {SNA} B, Bioactive Small Molecule Alphabetical Index, Cyclic Nucleotide Metabolism, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, G Proteins and Cyclic Nucleotides, P to Q, Phosphodiesterase 3',5'-Cyclic Nucleotide, Phosphodiesterase Inhibitors, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 酶、抑制剂和底物

相关文献及参考

  • Huang, et al., Diminished basal phosphorylation level of phospholamban in the postinfarction remodeled rat ventricle : role of beta-adrenergic pathway, G(i) protein, phosphodiesterase, and phosphatases. Circ. Res. 85 , 848-855, (1999) 摘要
  • Lu, et al., Masking of forskolin-induced long-term potentiation by adenosine accumulation in area CA1 of the rat hippocampus. Neuroscience 88 , 69-78, (1999) 摘要
  • Zhu, et al., Cyclic AMP-specific phosphodiesterase inhibitor rolipram and RO-20-1724 promoted apoptosis in HL60 promyelocytic leukemic cells via cyclic AMP-independent mechanism. Life Sci. 63 , 265-274, (1998) 摘要
  • Begstrand, H., et al. Mol. Pharmacol. 13 , 38, (1977) 摘要
  • Bodrato, N., et al., Abscisic Acid Activates The Murine Microglial Cell Line N9 Through The Second Messenger Cyclic ADP-ribose. J. Thorac. Cardiovasc. Surg. 284 , 14777-87, (2009) 摘要
  • Garavaglia, A., et al., Adaptation Of NS Cells Growth And Differentiation To High-throughput Screening-compatible Plates. BMC Neurosci. 11 , 7, (2010) 摘要

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Signal word Warning
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Hazard Codes Xi
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Inhibitors - Enzymes, Inhibitors, and Substrates
  5. Enzyme Inhibitors by Enzyme - Enzyme Inhibitors
  6. P to Q - Enzyme Inhibitors by Enzyme
  7. Phosphodiesterase 3′,5′-Cyclic Nucleotide - P to Q
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. G Proteins and Cyclic Nucleotides - Cell Signaling and Neuroscience
  5. Cyclic Nucleotide Metabolism - G Proteins and Cyclic Nucleotides
  6. Phosphodiesterase Inhibitors - Cyclic Nucleotide Metabolism
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. G Proteins and Cyclic Nucleotides - Cell Signaling and Neuroscience
  5. Cyclic Nucleotide Metabolism - G Proteins and Cyclic Nucleotides
  6. Phosphodiesterase Inhibitors - Cyclic Nucleotide Metabolism

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