Procyclidine hydrochloride Procyclidine

CAS 1508-76-5 MFCD00079236

化学结构图

1508-76-5
SMILES: Cl.OC(CCN1CCCC1)(c1ccccc1)C1CCCCC1

化学属性

Mol. FormulaC19H30ClNO
Mol. Weight324

别名和识别编码

Chemical Namehydrochloride United States Pharmacopeia (USP) Reference Standard Procyclidine Hydrochloride
CAS Number1508-76-5
Synonym (?)-Procyclidine Hydrochloride 1-Cyclohexyl-1-phenyl-3-pyrrolidino-1-propanol hydrochloride ?-Cyclohexyl-?-phenyl-1-pyrrolidinepropanol Hydrochloride Arpicolin Kemadrin Kemadrin Hydrochloride Kemadrin hydrochloride Os Procyclidine hydrochloride Tricyclamol hydrochloride alpha-Cyclohexyl-alpha-phenyl-1-pyrrolidinepropanol hydrochloride α-Cyclohexyl-α-phenyl-1-pyrrolidinepropanol
MDL NumberMFCD00079236
PubChem Substance ID24898455
EC Number216-141-8
Chemical Name TranslationProcyclidine
LabNetwork Molecule IDLN01300650
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分类

  • {SNA} Antagonists, Cell Signaling and Neuroscience, Cholinergics, Neuroscience, Neurotransmission, Neurotransmitters, 细胞生物学
  • Heterocycles
  • {SNA} Antagonists, Bioactive Small Molecule Alphabetical Index, Cholinergics, Neuroscience, Neurotransmission, Neurotransmitters, PI-PZ, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
  • Neurochemicals
  • Pharmaceuticals
  • {SNA} Antagonists, Cell Biology, Cell Signaling and Neuroscience, Cholinergics, Neuroscience, Neurotransmission, Neurotransmitters
  • Aromatics
  • Intermediates & Fine Chemicals,

产品应用

  • An anticholinergic drug used in the treatment parkinson?s disease. It is also used to treat patients suffering from drug-induced parkinsonism, akathisia and acute dystonia.

相关文献及参考

  • Salako, L.A.: Arch. Int. Pharmacodyn, Ther., 184, 233 (1970); Vas, C.J. et al.: Neurol., 19, 234 (1969);

安全信息

WGK Germany3
RTECSUY1926000
Storage condition 储存温度2-8°C 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 55 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 103,100,1955

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Neuroscience - Cell Signaling and Neuroscience
  5. Neurotransmission - Neuroscience
  6. Neurotransmitters - Neurotransmission
  7. Cholinergics - Neurotransmitters
  8. Antagonists - Cholinergics

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