Flurandrenolide 氟氢缩松

CAS 1524-88-5 MFCD00079290

化学结构图

1524-88-5
SMILES: CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)CC[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@]2(C(=O)CO)O1

化学属性

Mol. FormulaC24H33FO6
Mol. Weight437

别名和识别编码

Chemical NameFlurandrenolide
CAS Number1524-88-5
Synonym ######## 6α-Fluoro-11β,16α,17,21-tetrahydroxypregn-4-ene-3,20-dione 16,17-acetonide 6α-Fluoro-11β,16α,17,21-tetrahydroxypregn-4-ene-3,20-dione 16,17-acetonide Fludroxycortide Alondra-F Cordran Drenison Drocort Fluorandrenolone Fluorandrenolone acetonide Fluoroandrenolone acetonide Flurandrenolide Flurandrenolone Flurandrenolone acetonide Glucocorticoid Haelan Haldrone-F L 33379 Sermaka 氟氢缩松
MDL NumberMFCD00079290
PubChem Substance ID15209
EC Number216-196-8
Chemical Name Translation氟氢缩松
Wiswesser Line NotationT F5 E5 B666 GO IO RV PUTJ A1 CQ E1 FV1Q H1 H1 OF
LabNetwork Molecule IDLN01297487
InChIInChI=1S/C24H33FO6/c1-21(2)30-19-9-14-13-8-16(25)15-7-12(27)5-6-22(15,3)20(13)17(28)10-23(14,4)24(19,31-21)18(29)11-26/h7,13-14,16-17,19-20,26,28H,5-6,8-11H2,1-4H3/t13-,14-,16-,17-,19+,20+,22-,23-,24+/m0/s1
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分类

  • {SNA} Corticosteroid, Cytokines, Growth Factors and Hormones, Hormones, Steroid Hormones, 细胞信号转导和神经科学, 细胞生物学
  • {SNA} Cell Biology, Cell Signaling and Neuroscience, Corticosteroid, Cytokines, Growth Factors and Hormones, Hormones, Steroid Hormones
  • Steroids
  • Pharmaceuticals
  • {SNA} Cell Signaling and Neuroscience, Corticosteroid, Cytokines, Growth Factors and Hormones, Hormones, Steroid Hormones, 细胞生物学
  • Intermediates & Fine Chemicals

产品应用

  • Glucocorticoid; antipsoriatic.

相关文献及参考

  • Pearlman, R., et al.: Int. J. Pharm., 18, 53 (1984),
  • Neufeld, E., et al.: J. Chromatogr., 718, 273 (1998),

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P305+P351+P338
  • P337+P313
  • P337+P317
Hazard statements
  • H319 Causes serious eye irritation 严重刺激眼睛
RTECSTU5024800
Signal word Warning
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter 
TYPE OF TEST            : Mutation test systems - not otherwise specified
ROUTE OF EXPOSURE       : Administration onto the skin
TEST SYSTEM             : Human
DOSE/DURATION           : 19 mg/kg
REFERENCE :
   26UYA8 "Psoriasis, Proceedings of the International Symposium, Stanford, CA,
   1971," Farber, E.M., and A.J. Cox, eds., Stanford, CA, Stanford Univ. Press,
   1971  Volume(issue)/page/year: -,335,1971

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Cytokines, Growth Factors and Hormones - Cell Signaling and Neuroscience
  5. Hormones - Cytokines, Growth Factors and Hormones
  6. Steroid Hormones - Hormones
  7. Corticosteroid - Steroid Hormones

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