• 原料直供
• 试剂商城
• 直接询价

分类

• {SNA} A - K, Antibacterial, Antibiotics A to Z, Antibiotics A-F, Antibiotics by Application, Antineoplastic and Immunosuppressive Antibiotics, Chemical Structure Class, Interferes with Protein Synthesis, Mechanism of Action, Spectrum of Activity, Tetracyclines, 抗生素, 生化试剂
• {SNA} Analytical Standards, Chromatography, EP Standards, EP Standards C - D, Pharmaceutical Standards, Pharmacopeia Standards, 分析/色谱
• {SNA} 1694 Pharmaceuticals & Personal Care Products,
• {SNA} Analytical Standards, EP Standards, EP Standards C - D, Pharmacopeia Metrological Institutes Standards, 分析/色谱

产品应用

• 细胞渗透荧光探针，用于测量内质网Ca2+ 流量。

相关文献及参考

• Martinez, M., et al.: Biochemistry, 40, 11965 (2001),
• Skaletzki, B., et al.: Pharmazie, 29, 424 (1974),
• Merck: 14,2192
• Davidson, P., et al.: Food Technol., 55, 69 (2002),
• Merck: 14,2192 Beilstein: 14,IV,2631

安全信息

GHS Symbol

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED

T

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ANYAA9 Annals of the New York Academy of Sciences.  (New York Academy of
   Sciences, 2 E. 63rd St., New York, NY 10021)  V.1-    1877-
   Volume(issue)/page/year: 51,182,1948

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Lungs, Thorax, or Respiration - dyspnea
   Kidney, Ureter, Bladder - hematuria
REFERENCE :
   ANYAA9 Annals of the New York Academy of Sciences.  (New York Academy of
   Sciences, 2 E. 63rd St., New York, NY 10021)  V.1-    1877-
   Volume(issue)/page/year: 51,254,1948

TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : >50 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - nausea or vomiting
REFERENCE :
   ANYAA9 Annals of the New York Academy of Sciences.  (New York Academy of
   Sciences, 2 E. 63rd St., New York, NY 10021)  V.1-    1877-
   Volume(issue)/page/year: 51,182,1948

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 1125 mg/kg
SEX/DURATION            : female 10-18 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4
   per # born alive)
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses
   Filiales.  (SPPIF, B.P.22, F-41353 Vineuil, France)  V.1-    1849-
   Volume(issue)/page/year: 161,300,1967

其他信息

• Sigma Aldrich:64-72-2(sigmaaldrich)
• 用途一:属广谱抗生素，对革兰阳性和阴性菌均有抗菌作用
• 盐酸金霉素价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2010/06/21 430960050 盐酸金霉素 Chlortetracycline hydrochloride , conforms to Eur. Ph. 5 GR 473元 2010/06/21 430961000 盐酸金霉素 Chlortetracycline hydrochloride , conforms to Eur. Ph. 100 GR 3547元 2010/06/21 430960250 盐酸金霉素 Chlortetracycline hydrochloride , conforms to Eur. Ph. 25 GR 1253元
• 上游原料:盐酸 --> 淀粉 --> 酵母粉
• MSDS 信息:[4S-(4alpha,4aalpha,5aalpha,6beta,12aalpha)]-7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride(64-72-2).msds
• 用途三:细胞渗透荧光探针，用于测量内质网Ca2+ 流量。
• MOL 文件:64-72-2.mol
• Acros Organics:金霉素盐酸盐 Chlortetracycline hydrochloride, potency 900 ug/mg(64-72-2)
• 无臭，味苦；遇光色渐变暗。在水或乙醇中微溶，在丙酮、乙醚、二氧六环、丙二醇或氯仿中几乎不溶，溶于氢氧化物和碳酸盐碱溶液。溶解度:8.6 g/L 水(28°C)、17.4 g/L 甲醇(28°C), 1.7 g/L 乙醇(28°C)。
• 外观性质:金黄色或黄色结晶；无臭，味苦；遇光色渐变暗。在水或乙醇中微溶，在丙酮、乙醚、二氧六环、丙二醇或氯仿中几乎不溶，溶于氢氧化物和碳酸盐碱溶液。溶解度:8.6 g/L 水(28°C)、17.4 g/L 甲醇(28°C), 1.7 g/L 乙醇(28°C)。熔点：220℃ 比旋度为-235°至-250°
• 用途二:广谱抗生素，对革兰氏阳性和阴性菌均有抗菌作用。