2-(3,6-Diacetoxy-2,7-dichloro-9H-xanthen-9-yl)benzoic acid 2',7'-二氯二氢荧光素二乙酸酯

CAS 4091-99-0 MFCD00128955

化学结构图

4091-99-0
SMILES: CC(=O)Oc1cc2c(cc1Cl)C(c1ccccc1C(=O)O)c1cc(Cl)c(OC(C)=O)cc1O2

化学属性

Mol. FormulaC24H16Cl2O7
Mol. Weight487.29
Melting Point232
Stability空气敏感，光敏感

别名和识别编码

Chemical Name2-(3,6-Diacetoxy-2,7-dichloro-9H-xanthen-9-yl)benzoic acid
CAS Number4091-99-0
Synonym 2′,7′-Dichlorodihydrofluorescein diacetate 2',7'-Dichlorodihydrofluorescein Diacetate {} {} {} {} {} {} {} {} {} {} {} {} {TRC} H2DCFDA {} {} {} {} {} {} {} {} {} {} {} {} {} {ALD} DCFH-DA;2,7-二氯二氢荧光素二乙酸酯 {} {} {} {} {} {} {} {} {} {} {} {} {} {} {TRC} DCFH {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {PubChem} DCDHF-DA {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {JNK} 2′,7′-Dichlorodihydrofluorescein diacetate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {PubChem} 2',7'-dichlorodihydrofluorescein diacetate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {SNA} 2',7'-Dichlorodihydrofluorescein diacetate
MDL NumberMFCD00128955
PubChem Substance ID77718
Beilstein Registry Number4610273
Chemical Name Translation2',7'-二氯二氢荧光素二乙酸酯
InChIKeyPXEZTIWVRVSYOK-UHFFFAOYSA-N
LabNetwork Molecule IDLN00198559
InChIInChI=1S/C24H16Cl2O7/c1-11(27)31-21-9-19-15(7-17(21)25)23(13-5-3-4-6-14(13)24(29)30)16-8-18(26)22(32-12(2)28)10-20(16)33-19/h3-10,23H,1-2H3,(H,29,30)
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分类

  • {SNA} Alphabetical, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Cell Stress, Fluorescent Enzyme Substrates, Fluorescent Probes, Labels, Particles and Stains, Nitric Oxide and Cell Stress, Oxidative Stress Proteins and Reagents
  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Fluorescent Labels & Indicators
  • {SNA} Alphabetical, Bioactive Small Molecule Alphabetical Index, Cell Stress, D-DIF, Fluorescent Enzyme Substrates
  • Aromatics
  • {SNA} Alphabetical, Biochemicals and Reagents, Cell Signaling and Neuroscience, Cell Stress, Fluorescent Enzyme Substrates, Fluorescent Probes, Labels, Particles and Stains, Nitric Oxide and Cell Stress, Oxidative Stress Proteins and Reagents, 细

产品应用

  • 2',7'-Dichlorodihydrofluorescein as a cell-permeable non-fluorescent probe. It is de-esterified intracellularly and turns to highly fluorescent 2?,7?-dichlorofluorescein upon oxidation.

相关文献及参考

  • Baron, C., et al.: J. Agric. Food Chem., 57, 4185 (2009),
  • Kjaer, M., et al.: Lipids, 43, 813 (2008),
  • Lebel, C., et al.: Chem. Res. Toxicol., 5, 227 (1992),
  • [1]. Lyublinskaya OG, et al. Redox environment in stem and differentiated cells: A quantitative approach. Redox Biol. 2017 Aug;12:758-769.

安全信息

Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352
  • P304+P340
  • P305+P351+P338
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
  • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
  • P332+P313
  • P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
WGK Germany3
Signal word Warning
Hazard Codes Xi
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Storage condition -20°C -20℃ 储存温度 -20°C 储存温度 -20°C;充氩保存

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Fluorescent Probes, Labels, Particles and Stains - Biochemicals and Reagents
  4. Detection - Fluorescent Probes, Labels, Particles and Stains
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Fluorescent Probes, Labels, Particles and Stains - Biochemicals and Reagents
  4. Fluorescent Enzyme Substrates - Fluorescent Probes, Labels, Particles and Stains
  5. Alphabetical - Fluorescent Enzyme Substrates
  1. Medical Research Areas
  2. Metabolism
  3. Reactive Oxygen Species  (活性氧)

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