Chorionic gonadotropin human 绒毛膜促性激素 人

CAS 9002-61-3 MFCD00130797

化学结构图

9002-61-3
SMILES:

化学属性

Mol. Weight232.40422
Mol. FormulaC17H28

别名和识别编码

Synonym Pregnyl Gonabion Chorionic gonadotropic hormone 绒毛膜促性激素(HCG) Physex Choriogonadotropin Antuitrin S 绒促性素 Coriantin Praedyn Chorionic gonadotropin HCG Gonadex Chorulon Ambinon Chorionic gonadotropic hormone; Human chorionic gonadotrophin Choriogonin Chorigon HCG 绒毛膜促性腺激素 绒毛膜促性激素 人类 Randonos Apoidina 绒毛膜促性激素 人 Human chorionic gonadotropin Chorionic gonadotrophin APL APL (hormone) Korotrin Synaphorin
MDL NumberMFCD00130797
CAS Number9002-61-3
EC Number232-660-2
Chemical NameChorionic gonadotropin human
Chemical Name Translation绒毛膜促性激素 人
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分类

  • {SNA} Cell Biology, Cell Signaling and Neuroscience, Chorionic Gonadotropin, Cytokines, Growth Factors and Hormones, Hormones, Other Protein/Peptide Hormones
  • {SNA} Cell Signaling and Neuroscience, Chorionic Gonadotropin, Cytokines, Growth Factors and Hormones, Hormones, Other Protein/Peptide Hormones, 细胞生物学
  • {SNA} Chorionic Gonadotropin, Cytokines, Growth Factors and Hormones, Hormones, Other Protein/Peptide Hormones, 细胞信号转导和神经科学, 细胞生物学
  • Cell Biology, Cell Signaling and Neuroscience, Chorionic Gonadotropin, Cytokines, Growth Factors and Hormones, Hormones, Other Protein/Peptide Hormones

相关文献及参考

  • 1. Birken, S., et al., Immunochemical measurement of early pregnancy isoforms of HCG: potential applications to fertility research, prenatal diagnosis, and cancer Arch. Med. Res. 32 , 635-643, (2001)
  • Merck 14 ,2216

安全信息

RTECSMD6953000
Hazard Codes Xn B
WGK Germany3
GHS Symbol
Hazard statements
  • H361 Suspected of damaging fertility or the unborn child 怀疑对生育能力或未出生婴儿造成伤害
Personal Protective Equipment Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Precautionary statements
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
Signal word Warning
Storage condition 储存温度-20°C
Safety Statements
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
  • S22 Do not breathe dust 不要吸入粉尘;
Risk Statements
  • R63 Possible risk of harm to the unborn child 可能危害未出生婴儿
  • R62 Possible risk of impaired fertility 有削弱生殖能力的危险
TYPE OF TEST            : Sperm Morphology
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Non-mammalian species
DOSE/DURATION           : 18 mg/kg/2D
REFERENCE :
   ENDKAC Endokrinologie.  (Leipzig, Ger. Dem. Rep.)  V.1-80, 1928-82.  For
   publisher information, see EXCEDS.  Volume(issue)/page/year: 67,167,1976

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - hamster
DOSE                    : 60 mg/kg
SEX/DURATION            : female 4-6 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   ENDOAO Endocrinology (Baltimore).  (Williams & Wilkins Co., 428 E. Preston
   St., Baltimore, MD 21203) V.1-    1917-  Volume(issue)/page/year:
   83,217,1968

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 8890 ug/kg
SEX/DURATION            : female 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
REFERENCE :
   GOBIDS Gynecologic and Obstetric Investigation.  (S. Karger Pub., Inc., 79
   Fifth Ave., New York, NY 10003)  V.9-    1978-  Volume(issue)/page/year:
   22,84,1986

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 16 mg/kg
SEX/DURATION            : male 4 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - other effects on male
REFERENCE :
   IJMRAQ Indian Journal of Medical Research.  (Indian Council of Medical
   Research, Ansari Nagar, New Delhi 110 029, India)  V.1-    1913-
   Volume(issue)/page/year: 66,597,1977

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 83 ug/kg
SEX/DURATION            : female 9 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implan

其他信息

  • www.aladdin-reagent.comWhen reconstituted with 10 mL water each vial will also contain 25 mg of mannitol in 0.01 M sodium phosphate buffer at approx. pH 7.2.

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