Filipin complex from Streptomyces filipinensis

CAS 11078-21-0 MFCD00131073

化学结构图

11078-21-0
SMILES:

别名和识别编码

MDL NumberMFCD00131073
CAS Number11078-21-0
Chemical NameFilipin complex from Streptomyces filipinensis
Synonym Filipin complex 14-Deoxylagosin Filimirasin Filmirisin
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • Antibiotics, Antibiotics A to Z, Antibiotics A-F, Antifungal, Application Index, Biochemicals and Reagents, Chemical Structure Class, Enzymes, Inhibitors, and Substrates, Filipin complex, Interferes with Cell Membrane Permeability (Ionophores), Macrolides, Mechanism of Action, Plasma & Blood Proteins, Plasma, Blood, and Related Proteins and Reagents, Proteins and Derivatives, Serum Proteins, Serum Proteins and Related Enzymes, Spectrum of Activity
  • {SNA} Antibiotics A to Z,
  • {SA} Antibiotics, Antibiotics A to Z, Antibiotics A-F, Antifungal, Application Index, Biochemicals and Reagents,
  • {SNA} Antibi

相关文献及参考

  • 1. Kawasaki, S., et al., Sterol control of the phosphatidylethanolamine-phosphatidylcholine conversion in the yeast mutant GL7. Proc. Natl. Acad. Sci. U. S. A. 82 , 5715-9 , (1985) 摘要
  • 2. Lopes, S.C., et al., Filipin orientation revealed by linear dichroism. Implication for a model of action J. Am. Chem. Soc. 126 , 5396-5402, (2004) 摘要
  • 3. Marella, M., et al., Filipin prevents pathological prion protein accumulation by reducing endocytosis and inducing cellular PrP release. J. Biol. Chem. 277 , 3737-47, (2002) 摘要
  • Halliday, G.M., et al., {alpha}-Synuclein redistributes to neuromelanin lipid in the substantia nigra early in Parkinson's disease Brain 128 , 2654-64, (2005) 摘要
  • Merck 14 ,4080

安全信息

GHS Symbol
WGK Germany3
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Signal word Warning
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Hazard Codes Xi
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
RTECSLK4400000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 17 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 2,215,1980

系列性分类

  1. Life Science 生命科学
  2. Antibiotics 抗生素
  3. Antibiotics A to Z - Antibiotics
  4. Antibiotics A-F - Antibiotics A to Z
  1. Life Science 生命科学
  2. Antibiotics 抗生素
  3. Antibiotics A to Z - Antibiotics
  4. Antibiotics G-M - Antibiotics A to Z
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Proteins and Derivatives - Biochemicals and Reagents
  4. Plasma & Blood Proteins - Proteins and Derivatives
  5. Plasma, Blood, and Related Proteins and Reagents - Plasma & Blood Proteins
  6. Filipin complex - Plasma, Blood, and Related Proteins and Reagents

相关产品推荐