Purine nucleoside phosphorylase, 200 units/mg 核苷磷酸化酶

CAS 9030-21-1 MFCD00131739

化学结构图

9030-21-1
SMILES: Nc1cnc(Cl)cc1N

化学属性

Density1.422
Mol. Weight
Mol. FormulaN/A

别名和识别编码

MDL NumberMFCD00131739
CAS Number9030-21-1
Synonym Deoxyribonucleoside phosphorylase; Purine deoxynucleoside phosphorylase; Purine deoxyribonucleoside phosphorylase; Purine nucleoside phosphorylase; Purine ribonucleoside phosphorylase Nucleoside Phosphorylase bacterial PNP PNP Purine nucleoside:orthophosphate ribosyltransferase 嘌呤核苷磷酸化酶 PNP Purine nucleoside:orthophosphate ribosyltransferase 嘌呤核苷磷酸化酶 核苷磷酸化酶 细菌 Purine nucleoside:orthophosphate ribosyltransferase nucleoside phosphorylase 嘌呤核苷磷酸化酶 核苷磷酸化酶 来源于微生物 核苷磷酸化酶 细菌
EC Number232-857-3
Beilstein Registry Number2384789
Chemical NamePurine nucleoside phosphorylase, 200 units/mg
Chemical Name Translation核苷磷酸化酶
PubChem Substance ID817133
InChIInChI=1S/C5H6ClN3/c6-5-1-3(7)4(8)2-9-5/h1-2H,8H2,(H2,7,9)
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分类

  • {SNA} 2.4.x.x Glycosyltransferases, 2.x.x.x Transferases, Chemical Synthesis, Enzyme Class Index, Enzyme-Mediated Synthesis, General Metabolic Enzymes, Nucleotide Metabolism, Specialty Synthesis, Transferases, 代谢组学, 生化试剂, 细胞生物学,

相关文献及参考

  • Keystone E.C., et al, Golimumab, a human antibody to tumour necrosis factor {α} given by monthly subcutaneous injections, in active rheumatoid arthritis despite methotrexate therapy: the GO-FORWARD Study. Ann. Rheum. Dis. 68(6) , 789-96, (2009)
  • Drake, E.J., et al, Biochemical and structural characterization of bisubstrate inhibitors of BasE, the self-standing nonribosomal peptide synthetase adenylate-forming enzyme of acinetobactin synthesis. Biochemistry 49(43) , 9292-305, (2010)
  • Wilson, D.J. and Aldrich, C.C., A continuous kinetic assay for adenylation enzyme activity and inhibition. Anal. Biochem. 404(1) , 56-63, (2010)

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Signal word Warning
GHS Symbol
Safety Statements
  • S22 Do not breathe dust 不要吸入粉尘;
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P285 In case of inadequate ventilation wear respiratory protection. 在通风不足的情况下,戴呼吸防护。
  • P302+P352
  • P304+P340
  • P304+P341
  • P305+P351+P338
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P332+P313
  • P337+P313
  • P342+P311
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled 吸入可能导致过敏或哮喘症状或呼吸困难
  • H335 May cause respiratory irritation 可能导致呼吸道刺激

系列性分类


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