Pancreatin 胰酶

CAS 8049-47-6 MFCD00131789

化学结构图

8049-47-6
SMILES:

化学属性

Mol. Formula-
Mol. Weight-
TSCAYes
Stability对光敏感

别名和识别编码

CAS Number8049-47-6
MDL NumberMFCD00131789
Synonym Pancreatin from Porcine Pancreas {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {SNA} 胰液素 来源于猪胰腺 胰酵素,胰醇素,胰液素 胰酶 胰酶 来源于猪胰腺 胰酶; 胰酵素 胰酶;胰酵素;胰醇素;胰液素来源于猪胰腺
EC Number232-468-9
Chemical NamePancreatin
Merck Number7006
Chemical Name Translation胰酶
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分类

  • {SNA} Biochemicals and Reagents, Enzymes, Inhibitors, and Substrates, Prot
  • {SNA} Application Index, Biochemicals and Reagents, Cell Culture, Cell Dissociation, Cell Dissociation (Cell Culture Tested), Cell Dissociation and Cell Lysis, Enzymes, Enzymes, Inhibitors, and Substrates, Reagents and Supplements
  • {SNA} Application Index, Biochemicals and Reagents, Cell Dissociation, Cell Dissociation and Cell Lysis, 酶、抑制剂和底物
  • {SNA} Core Bioreagents, Core Bioreagents Enzymes, Research Essentials
  • {SNA} Application Index, Biochemicals and Reagents,
  • {SNA} Application Index, Cell Dissociation, Cell Dissociation and Cell Lysis, 生化试剂, 酶、抑制剂和底物
  • {SNA} Application Index,
  • {SNA} Pro

产品应用

  • 酶反应:能转化不少于25倍量的酪蛋白成为 (在5分钟内,相当于在30分钟内150倍)。其最大活力在中性或微碱性介质中。矿酸或过量氢氧化物或碳酸盐使之失活。

相关文献及参考

  • Merck: 14,7006

安全信息

GHS Symbol
WGK Germany1
Precautionary statements
  • P342+P311
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled 吸入可能导致过敏或哮喘症状或呼吸困难
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Signal word
RTECSRT9033000
Hazard Codes Xn
Safety Statements
  • S22 Do not breathe dust 不要吸入粉尘;
  • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S24 Avoid contact with skin 避免皮肤接触;
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R42 May cause sensitisation by inhalation 吸入会产生过敏反应
  • R42/43
Storage condition 储存温度 -20°C避光保存 储存温度 -20°C
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2100 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - ptosis
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   YACHDS Yakuri to Chiryo.  Pharmacology and Therapeutics.  (Raifu Saiensu
   Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan)  V.1-    1972-
   Volume(issue)/page/year: 3,2427,1975

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >10 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YACHDS Yakuri to Chiryo.  Pharmacology and Therapeutics.  (Raifu Saiensu
   Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan)  V.1-    1972-
   Volume(issue)/page/year: 3,2427,1975

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >10 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YACHDS Yakuri to Chiryo.  Pharmacology and Therapeutics.  (Raifu Saiensu
   Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan)  V.1-    1972-
   Volume(issue)/page/year: 3,2427,1975

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3870 mg/kg
TOXIC EFFECTS :
   Skin and Appendages - hair
REFERENCE :
   YACHDS Yakuri to Chiryo.  Pharmacology and Therapeutics.  (Raifu Saiensu
   Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan)  V.1-    1972-
   Volume(issue)/page/year: 3,2427,1975

其他信息

  • 微臭,但无霉败的臭气;有引湿性,是以胰蛋白酶、胰淀粉酶、胰脂肪酶为主所组成的多种酶的混合物,水溶液煮沸或遇酸即失去酶活力。本品在中性或弱碱性环境中(酸碱度6.8~8.5)可促进蛋白质、淀粉及脂肪的消化。有吸湿性。溶于水呈微浑溶液,不溶于乙醇和乙醚。

系列性分类


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