ACTH [1-17] ACTH [1-17]

CAS 7266-47-9 MFCD00133033

化学结构图

7266-47-9
SMILES: CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O)C(C)C

化学属性

Mol. FormulaC95H145N29O23S
Mol. Weight2093.41

别名和识别编码

Chemical NameACTH [1-17]
MDL NumberMFCD00133033
CAS Number7266-47-9
Synonym 1-Ala-17-Lys-ACTH 4-amino-n-butylamide 1-beta-Alanine-17-(L-2,6-diamino-N-(4-aminobutyl)hexanamide)-alpha1-17-corticotrophin ACTH (1-17) ACTH (1-17), human ACTH 4-amino-n-butylamide (1-17), Ala(1)-Lys(17)- ACTH 4-amino-n-butylamide (1-17), alanyl(1)-lysine(17)- ACTH(1-17) AL-ACTH(1-17)AB Synchrodyn alsactide
Chemical Name TranslationACTH [1-17]
LabNetwork Molecule IDLN02124577
PubChem Substance ID71312141
InChIInChI=1S/C95H145N29O23S/c1-53(2)78(91(144)109-49-75(128)111-62(22-9-12-35-96)81(134)113-63(23-10-13-36-97)82(135)117-68(93(146)147)26-16-39-106-95(102)103)123-90(143)74-27-17-40-124(74)92(145)67(24-11-14-37-98)112-76(129)48-108-80(133)71(44-56-46-107-61-21-8-7-20-59(56)61)120-83(136)64(25-15-38-105-94(100)101)114-86(139)70(42-54-18-5-4-6-19-54)119-88(141)72(45-57-47-104-52-110-57)121-84(137)65(32-33-77(130)131)115-85(138)66(34-41-148-3)116-89(142)73(51-126)122-87(140)69(118-79(132)60(99)50-125)43-55-28-30-58(127)31-29-55/h4-8,18-21,28-31,46-47,52-53,60,62-74,78,107,125-127H,9-17,22-27,32-45,48-51,96-99H2,1-3H3,(H,104,110)(H,108,133)(H,109,144)(H,111,128)(H,112,129)(H,113,134)(H,114,139)(H,115,138)(H,116,142)(H,117,135)(H,118,132)(H,119,141)(H,120,136)(H,121,137)(H,122,140)(H,123,143)(H,130,131)(H,146,147)(H4,100,101,105)(H4,102,103,106)/t60-,62-,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,78-/m0/s1
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分类

  • Adrenocorticotrophic Hormone (ACTH), Adrenocorticotropic Hormones (ACTH), Cell Biology, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, Hormones, Peptides and Proteins, Peptides for Cell Biology, Pituitary Hormones
  • {SNA} Adrenocorticotrophic Hormone (ACTH), Adrenocorticotropic Hormones (ACTH), Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, Hormones, Peptides and Proteins, Peptides for Cell Biology, Pituitary Hormones, 细胞生物学
  • {SNA} Adrenocorticotrophic Hormone (ACTH), Adrenocorticotropic Hormones (ACTH), Cytokines, Growth Factors and Hormones, Hormones, Peptides and Proteins,
  • {SNA} Adrenocorticotrophic Hormone (ACTH),
  • {SNA} Adrenocorticotrophic Hormone (ACTH),

产品应用

  • ACTH fragment with moderate adrenocorticotropic and melanocyte-stimulating activities.

相关文献及参考

  • [2]. Ceda GP, et al. The effects of ACTH (1-17) on GH secretion in vitro. Horm Metab Res. 1987 Aug;19(8):361-3.
  • [3]. Walker WV, et al. Effect of an adrenocorticotropin analogue, ACTH (1-17), on DNA synthesis in murine metaphyseal bone. Biochem Pharmacol. 1985 Apr 15;34(8):1191-6.
  • [1]. Tsatmali M et al. ACTH1-17 is a more potent agonist at the human MC1 receptor than alpha-MSH. Cell Mol Biol (Noisy-le-grand). 1999 Nov;45(7):1029-34.
  • [1]. Tsatmali M et al. ACTH1-17 is a more potent agonist at the human MC1 receptor than alpha-MSH. Cell Mol Biol (Noisy-le-grand). 1999 Nov;45(7):1029-34.
  • [2]. Ceda GP, et al. The effects of ACTH (1-17) on GH secretion in vitro. Horm Metab Res. 1987 Aug;19(8):361-3.
  • [3]. Walker WV, et al. Effect of an adrenocorticotropin analogue, ACTH (1-17), on DNA synthesis in murine metaphyseal bone. Biochem Pharmacol. 1985 Apr 15;34(8):1191-6.

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage condition 储存温度:-20°C

其他信息

  • 氨基酸序列
  • 氨基酸序列 Ser-Tyr-Ser-Met-Glu-His-P?he-Arg-Trp-Gly-Lys-Pro-Va?l-Gly-Lys-Lys-Arg

系列性分类


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