Sucralfate 硫糖铝
CAS 54182-58-0 MFCD00145339
化学结构图
SMILES: [O-]S(=O)(=O)OC[C@H]1O[C@@H](O[C@]2(COS([O-])(=O)=O)O[C@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O.O[Al](O)O.O[Al](O)O.O[Al](O)O.O[Al](O)O.O[Al](O)O.O[Al](O)O.O[Al](O)O.O[Al](O)O.O[AlH2-]O.O[AlH2-]O.O[AlH2-]O.O[AlH2-]O.O[AlH2-]O.O[AlH2-]O.O[AlH2-]O.O[AlH2-]O
化学属性
| Mol. Formula | C12H54Al16O75S8 |
|---|---|
| Mol. Weight | 2087 |
别名和识别编码
| Chemical Name | Sucralfate |
|---|---|
| CAS Number | 54182-58-0 |
| Synonym | Sulcrate Venter Sucralfin Sucrate Ulcogant Sucralfate Antepsin Sugast Ulcermin Keal Succosa Carafate Ulcerlmin Ulcar Hexagastron Citogel Sucrose Octasulfate Aluminium Salt Urbal |
| EC Number | 259-018-4 |
| Chemical Name Translation | 硫糖铝 |
| MDL Number | MFCD00145339 |
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分类
- Inhibitors
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Oligosaccharides; Sulfur & Selenium Compounds,
产品应用
- An inhibitor of peptic hydrolysis and stomach acidity. Used as an antiulcerative.
相关文献及参考
- Mayberr, J.F., et al.: Brit. J. Clin. Pract., 32, 291 (1978),
- Brogden, R.N., et al.: Drugs, 27, 194 (1984),
安全信息
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >8 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,374,1982
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >8 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,374,1982
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >8 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Jap
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >12 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,374,1982
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >4 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,374,1982
TYPE
GHS Symbol
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