Charybdotoxin

CAS 95751-30-7 MFCD00146378

化学结构图

95751-30-7
SMILES: CSCC[C@@H]1NC(=O)[C@@H]2CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]3CCC(=O)N3)[C@@H](C)O)C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@H]3CSSC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC1=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c4ccccc14)NC3=O)C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[n]c[nH]1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N2)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(O)=O

化学属性

Mol. Weight4295.89
Mol. FormulaC176H277N57O55S7

别名和识别编码

MDL NumberMFCD00146378
CAS Number95751-30-7
Chemical NameCharybdotoxin
Synonym Charybdotoxin
InChIKeyCNVQLPPZGABUCM-LIGYZCPXSA-N
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分类

  • {SNA} Ion Channel Modulating Peptides, Ion Channels, Monovalent Ion Channels, Peptides and Proteins, Peptides for Cell Biology, Potassium Channel Modulators, Scorpion, Toxins and Venoms, Voltage-gated Ion Channels, 细胞信号转导和神经科学, 细胞生物学
  • Bioactive Small Molecules, C-CH, Cell Biology, Cell Signaling and Neuroscience, Ion Channel Modulating Peptides, Ion Channels, Monovalent Ion Channels, Peptides and Proteins, Peptides for Cell Biology, Potassium Channel Modulators, Scorpion, Toxins and Venoms, Voltage-gated Ion Channels
  • {SNA} Bioactive Small Molecules,

相关文献及参考

  • Doughty, J.M., et al., Charybdotoxin and apamin block EDHF in rat mesenteric artery if selectively applied to the endothelium. Am. J. Physiol. 276 , H1107-H1112, (1999) 摘要
  • Hanner, M., et al., The β subunit of the high conductance calcium-activated potassium channel identification of residues involved in charybdotoxin binding. J. Biol. Chem. 273 , 16289, (1998) 摘要
  • Merck 14 ,2046

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Toxins and Venoms - Cell Signaling and Neuroscience
  5. Scorpion - Toxins and Venoms
  1. Ion Channel Modulating Peptides - Peptides for Cell Biology
  2. Potassium Channel Modulators - Ion Channel Modulating Peptides
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Ion Channels - Cell Signaling and Neuroscience
  5. Voltage-gated Ion Channels - Ion Channels
  6. Monovalent Ion Channels - Voltage-gated Ion Channels
  7. Potassium Channel Modulators - Monovalent Ion Channels

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