16,16-dimethyl Prostaglandin E2
CAS 39746-25-3 MFCD00151141
化学结构图
SMILES: CCCCC(C)(C)[C@@H](O)/C=C/[C@@H]1[C@@H](C/C=C\CCCC(O)=O)C(=O)C[C@@H]1O
化学属性
| Mol. Formula | C22H36O5 |
|---|---|
| Mol. Weight | 380.52 |
别名和识别编码
| Chemical Name | 16,16-Dimethylprostaglandin E2 |
|---|---|
| MDL Number | MFCD00151141 |
| PubChem Substance ID | 24893214 |
| CAS Number | 39746-25-3 |
| Synonym | (5Z,11-alpha,13E,15R)-11,15-Dihydroxy-16,16-dimethyl-9-oxoprosta-5,13-dien-1-oic acid 16,16-Dimethyl-PGE2 16,16-Dimethyl-pge2 16,16-Dimethyl-prostaglandin E2 5-Heptenoic acid, 7-(2-(4,4-Dimethyl-3-hydroxy-1-octenyl)-3-hydroxy-5-oxocyclopentyl)-5-heptenoic acid |
| Beilstein Registry Number | 2896843 |
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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现货库存
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分类
- {SNA} Eicosanoids (Prostaglandins, Leukotrienes), Fatty Acyls, Prostaglandins, Small Molecules for Stem Cell Biology, 干细胞生物学, 生化试剂, 细胞生物学, 脂类
- {SA} Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, DIG-DY, Eicosanoids (Prostaglandins, Leukotrienes), Fatty Acyls, Lipids, Prostaglandins, Small Molecules for Stem Cell Biology, Stem Cell Biology
- Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, DIG-DY, Eicosanoids (Prostaglandins, Leukotrienes), Fatty Acyls, Lipids, Prost
相关文献及参考
- [2]. Roulis M, et al. Intestinal myofibroblast-specific Tpl2-Cox-2-PGE2 pathway links innate sensing to epithelial homeostasis. Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):E4658-67.
- [1]. Hagedorn EJ, et al. Getting more for your marrow: boosting hematopoietic stem cell numbers with PGE2. xp Cell Res. 2014 Dec 10;329(2):220-6.
- [1]. Hagedorn EJ, et al. Getting more for your marrow: boosting hematopoietic stem cell numbers with PGE2. xp Cell Res. 2014 Dec 10;329(2):220-6.
- [2]. Roulis M, et al. Intestinal myofibroblast-specific Tpl2-Cox-2-PGE2 pathway links innate sensing to epithelial homeostasis. Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):E4658-67.
安全信息
GHS Symbol
- P304+P340+P312
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P305+P351+P338
- P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
- P337+P313
- P403+P235
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- H336 May cause drowsiness or dizziness 肯能导致嗜睡或头晕
- H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
- H319 Causes serious eye irritation 严重刺激眼睛
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravaginal SPECIES OBSERVED : Human - woman DOSE : 64 ug/kg SEX/DURATION : female 6 week(s) after conception TOXIC EFFECTS : Reproductive - Fertility - abortion REFERENCE : CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 16,167,1977
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - woman DOSE : 4 ug/kg SEX/DURATION : female 34 week(s) after conception TOXIC EFFECTS : Reproductive - Fertility - abortion Reproductive - Effects on Embryo or Fetus - fetal death REFERENCE : PRGLBA Prostaglandins. (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022) V.1- 1972- Volume(issue)/page/year: 6,349,1974
- R11 Highly flammable 非常易燃
- R36 Irritating to eyes 刺激眼睛
- R66 Repeated exposure may cause skin dryness or cracking 反复接触可能导致皮肤干燥或皴裂
- R67 Vapours may cause drowsiness and dizziness 蒸汽可能导致嗜睡和昏厥
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S16 Keep away from sources of ignition - No smoking 远离火源，禁止吸烟；
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