9,18-(Iminoethaniminoethaniminoethaniminomethano)pyrrolo(1',2':8,9)(1,5,8, 11,14)thiatetraazacyclooctadecino(18,17-b)indole-6-acetic acid,1,2,3,5,6,7,8,9,10,12,17,18,19,20,21,22,23,23a-octadecahydro-29-sec-butyl-2,14-dihydroxy-21-(2,3-dihydroxy-1-methylpr opyl)-5,8,20,23,24,27,30,33-octaoxo-, 11-oxide

CAS 21150-22-1 MFCD00151212

化学结构图

21150-22-1
SMILES: CCC(C)[C@@H]1NC(=O)CNC(=O)[C@@H]2CC3C4C=CC(O)=CC=4NC=3S(=O)C[C@@H](NC(=O)CNC1=O)C(=O)N[C@@H](CC(O)=O)C(=O)N1CC(O)C[C@H]1C(=O)N[C@@H]([C@@H](C)[C@@H](O)CO)C(=O)N2 |&1:4,12,27,38,50,54,55,57|

化学属性

Mol. FormulaC39H53N9O15S
Mol. Weight919.95

别名和识别编码

Chemical Nameβ-Amanitin from Amanita phalloides
MDL NumberMFCD00151212
PubChem Substance ID24890528
EC Number244-244-8
Synonym alpha-Amanitin, 1-L-aspartic acid- beta-Amanitin beta-Amanitine β-Amanitin from Amanita phalloides beta-Amatoxin
CAS Number21150-22-1
Beilstein Registry Number1071139
Chemical Name Translation
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SNA} A-AM, Bioactive Small Molecule Alphabetical Index, DNA-RNA Transcription Regulators, Gene Regulation and Expression, Mushroom, Toxins and Venoms, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
  • {SNA} A-AM, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, DNA-RNA Transcription Regulators, Gene Regulation and Expression, Mushroom, Toxins and Venoms

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
  • P302+P350
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
Hazard statements
  • H330 Fatal if inhaled 吸入致命
  • H310 Fatal in contact with skin 皮肤接触致命
  • H300 Fatal if swallowed 吞食致命
RTECSNJ8324000
Signal word Danger
Hazard Codes T+
Safety Statements
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后，立即用大量…（由生产厂家指定）冲洗；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
  • S7 Keep container tightly closed 保存在严格密闭容器中；
Risk Statements
  • R26/27/28 Very toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有剧毒
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 22,2142,1972

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NEJMAG New England Journal of Medicine.  (Massachusetts Medical Soc., 10
   Shattuck St., Boston, MA 02115)  V.198-    1928-  Volume(issue)/page/year:
   269,223,1963

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Gene Regulation and Expression - Cell Signaling and Neuroscience
  5. DNA-RNA Transcription Regulators - Gene Regulation and Expression
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Toxins and Venoms - Cell Signaling and Neuroscience
  5. Mushroom - Toxins and Venoms

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