Oxytetracycline Dihydrate 土霉素二水合物

CAS 6153-64-6 MFCD00151234

化学结构图

6153-64-6
SMILES: CN(C)[C@@H]1C(O)=C(C(N)=O)C(=O)[C@@]2(O)C(O)=C3C(=O)c4c(O)cccc4[C@@](C)(O)[C@H]3[C@H](O)[C@@H]12.O.O

化学属性

Mol. FormulaC22H28N2O11
Mol. Weight496
Melting Point181-182
Solubility略溶于水
Appearance crystalline

别名和识别编码

Chemical NameOxytetracycline Dihydrate
MDL NumberMFCD00151234
CAS Number6153-64-6
PubChem Substance ID24898000
EC Number201-212-8
Synonym 多西环素 脱氧土霉素 DOXYCYCLINE USP 23 terramycin DOXYCYCLINE HYCHLATE 地霉素 5-hydroxytetracycline 氧四环素/土霉素 二水合物 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-, dihydrate, (4S,4aR,5S,5aR,6S,12aS)- DOXYCYCLINE HYDRATE BP98 USP23 4-二甲氨基-1,4,4a,5,5a,6,11,12a-八氢-3,5,6,10,12,12a-六羟基-6-甲基-1,11-二氧代-并四苯-2-甲酰胺二水合物 4-二甲氨基-1,4,4a,5,5a,6,11,12a-八氢-3,5,6,10,12,12a-六羟基-6-甲基-1,11-二氧代-并四苯-2-甲酰胺 强力霉素 土霉素 OXYTETRACYCLINE DIHYDRATE, ORAL GRADE OxytetracyclineHcl2058-46-0, OXYTETRACYCLINE HCL BP OXYTETRACYCLINE DIHYDRATE, INJECTABLE GRADE 氧四环素 OXYCYCLINE OXYTETRACYCLINE DIHYDRATE 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide dihydrate 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide dihydrate OXYTETRACYCLINE DIHYDRATE SIGMAULTRA trramycin DOXYCYCLINE HCL ( VETERINARY) 土霉素碱 6-甲基-4-(二甲氨基)-3,5,10,12,12a-五羟基-1,11-二氧代-1,4,4a,5,5a,6,11,12a-八氢-2-并四苯甲酰胺 土霉素注射液 二水合土霉素 土霉素 二水合物 OXYTETRACYCLINEFEED 土霉素二水合物
Chemical Name Translation土霉素二水合物
LabNetwork Molecule IDLN01343842
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分类

  • {SNA} Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics N-S, Antibiotics by Application,
  • {SNA} Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics N-S, Antibiotics by Application, Biochemicals and Reagents, Chemical Structure Class, Genetic Marker Selection, Interferes with Protein Synthesis, L - Z, Mechanism of Action, Spectrum of Activity, Tetracyclines
  • {SNA} Analytical Standards, Analytical/Chromatography, Chromatography, Pharmaceutical Standards, Pharmacopeia Standards, USP Standards, USP Standards N - O

产品应用

  • 阻止aminoacyl-tRNA结合到30S亚单元上，抑制蛋白质合成（延长期）。
  • 抗菌谱: 革兰氏阴性和阳性菌

相关文献及参考

  • [2]. Pickens LB, et al. Oxytetracycline biosynthesis. J Biol Chem. 2010 Sep 3;285(36):27509-15.
  • [3]. Oguz Guvenmez, et al. A New Treatment Method for Herpes Simplex Virus Type 1-related Skin Lesions. Scientific & Academic. 2019; 8(1): 6-8.
  • [1]. Elia AC, et al. Transferability of oxytetracycline (OTC) from feed to carp muscle and evaluation of the antibiotic effects on antioxidant systems in liver and kidney. Fish Physiol Biochem. 2014 Aug;40(4):1055-68.
  • [1]. Elia AC, et al. Transferability of oxytetracycline (OTC) from feed to carp muscle and evaluation of the antibiotic effects on antioxidant systems in liver and kidney. Fish Physiol Biochem. 2014 Aug;40(4):1055-68.
  • [2]. Pickens LB, et al. Oxytetracycline biosynthesis. J Biol Chem. 2010 Sep 3;285(36):27509-15.
  • [3]. Oguz Guvenmez, et al. A New Treatment Method for Herpes Simplex Virus Type 1-related Skin Lesions. Scientific & Academic. 2019; 8(1): 6-8.

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Hazard Codes Xn
Safety Statements
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
Risk Statements
  • R63 Possible risk of harm to the unborn child 可能危害未出生婴儿
  • R36 Irritating to eyes 刺激眼睛
Storage condition 0-6°C
Signal word
GHS Symbol
Precautionary statements

其他信息

  • Sigma Aldrich:6153-64-6(sigmaaldrich)
  • MOL 文件:6153-64-6.mol
  • color:yellow
  • 比旋光度:-216 ° (c=1,0.1 M HCl)
  • Acros Organics:土霉素二水合物 Oxytetracycline dihydrate, 95%(6153-64-6)
  • 用途一:阻止aminoacyl-tRNA结合到30S亚单元上，抑制蛋白质合成（延长期）。抗菌谱: 革兰氏阴性和阳性菌
  • 地霉素价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2010/06/21 123841000 地霉素 Oxytetracycline dihydrate 95% 100 GR 4263元 2010/06/21 123840100 地霉素 Oxytetracycline dihydrate 95% 10 GR 590元

系列性分类

  1. Life Science 生命科学
  2. Antibiotics 抗生素
  1. Life Science 生命科学
  2. Antibiotics 抗生素
  3. Antibiotics A to Z - Antibiotics
  4. Antibiotics N-S - Antibiotics A to Z
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Antibiotics
  4. Chemical Structure Class
  5. Taxoides
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Antibiotics
  4. Mechanism of Action
  5. Interferes with DNA Synthesis
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Antibiotics
  4. Antibiotics by Application
  5. Chemical Structure
  6. Tetracyclines
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Antibiotics
  4. Spectrum of Activity
  5. Antibacterial
  6. A - K
  1. Medical Research Areas
  2. Metabolism
  3. Endogenous Metabolite  (内源性代谢物)

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