(R)-(5-methyl-3-(morpholinomethyl)-2,3-dihydro-[1,4]oxazino[2,3,4-hi]indol-6-yl)(naphthalen-1-yl)methanone methanesulfonate (R)-(+)-WIN 55,212-2 mesylate salt
CAS 131543-23-2 MFCD00153882
化学结构图
SMILES: CC1=C(C(=O)C2C=CC=C3C=CC=CC3=2)C2C=CC=C3OC[C@@H](CN4CCOCC4)N1C=23.CS(O)(=O)=O
化学属性
| Mol. Formula | C27H26N2O3· CH3SO3H |
|---|---|
| Mol. Weight | 522.61 |
别名和识别编码
| Chemical Name | (R)-(5-methyl-3-(morpholinomethyl)-2,3-dihydro-[1,4]oxazino[2,3,4-hi]indol-6-yl)(naphthalen-1-yl)methanone methanesulfonate |
|---|---|
| Synonym | (R)-(+)-WIN 55,212-2 mesylate salt (R)-(+)-[2,3-Dihydro-5-methyl-3[(4-morpholinyl)methyl]pyrrolo[1,2,3-de]-1,4-benzoxazinyl]-(1-naphthalenyl)methanone mesylate salt (R)-(+)-[2,3-Dihydro-5-methyl-3[(4-morpholinyl)methyl]pyrrolo[1,2,3-de]-1,4-benzoxazinyl]-(1-naphthalenyl)methanone mesylate salt WIN 55212-2 methanesulfonate WIN552122 甲磺酸酯 WIN 55212-2 methanesulfonate WIN552122 甲磺酸酯 |
| MDL Number | MFCD00153882 |
| PubChem Substance ID | 24278779 |
| Chemical Name Translation | (R)-(+)-WIN 55,212-2 mesylate salt |
| CAS Number | 131543-23-2 |
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分类
- {SNA} Bioactive Small Molecule Alphabetical Index, Cannabinoids, Neurobiology, Neuroscience, Pharmacologicals, W, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
- {SNA} Bioactive Small Molecules, Cannabinoids, Cell Biology, Cell Signaling and Neuroscience, Neurobiology, Neuroscience, Pharmacologicals, W
相关文献及参考
- [2]. Ferraro L, et al. The cannabinoid receptor agonist WIN 55,212-2 regulates glutamate transmission in rat cerebral cortex: an in vivo and in vitro study. Cereb Cortex. 2001 Aug;11(8):728-33.
- [3]. Price TJ, et al. Cannabinoid receptor-independent actions of the aminoalkylindole WIN 55,212-2 on trigeminal sensory neurons. Br J Pharmacol. 2004 May;142(2):257-66.
- [4]. Payandemehr B, et al. Involvement of PPAR receptors in the anticonvulsant effects of a cannabinoid agonist, WIN 55,212-2. Prog Neuropsychopharmacol Biol Psychiatry. 2015 Mar 3;57:140-5
- [1]. Felder CC, et al. Comparison of the pharmacology and signal transduction of the human cannabinoid CB1 and CB2 receptors. Mol Pharmacol. 1995 Sep;48(3):443-50.
- [1]. Felder CC, et al. Comparison of the pharmacology and signal transduction of the human cannabinoid CB1 and CB2 receptors. Mol Pharmacol. 1995 Sep;48(3):443-50.
- [2]. Ferraro L, et al. The cannabinoid receptor agonist WIN 55,2
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