Colony-stimulating factor 1

CAS 81627-83-0 MFCD00166591

化学结构图

81627-83-0
SMILES:

别名和识别编码

Synonym CSF-1 CSF-1 Lanimostim MCSF MGC31930 Macrophage Colony Stimulating Factor Cytokines, macrophage colony-stimulating factor M-CSF human MCSF Macrophage colony-stimulating factor Monocyte colony-stimulating factor
MDL NumberMFCD00166591
CAS Number81627-83-0
Chemical NameM-CSF human
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分类

  • {SNA} Cytokines and Growth Factors, Cytokines as adjuvants, Cytokines, Growth Factors and Hormones,
  • {SA} Cell Biology, Cell Culture, Cell Signaling and Neuroscience, Cytokines and Growth Factors, Cytokines as adjuvants, Cytokines, Growth Factors and Hormones, Growth Factors and Cytokines, Hematopoietic Cytokines, M-CSF, Reagents and Supplements, Vaccine Adjuvants, Vaccine Production
  • {SNA} Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones, Growth Factors and Cytokines, Hematopoietic Cytokines, M-CSF, 细胞信号转导和神经科学, 细胞培养, 细胞生物学, 试剂和添加剂
  • {SNA} Cell Biology, Cell Culture,

相关文献及参考

  • Wang, D., et al., Elevated Mitochondrial Reactive Oxygen Species Generation Affects the Immune Response via Hypoxia-Inducible Factor-1{alpha} in Long-Lived Mclk1+/- Mouse Mutants J. Immunol. 184 , 582-90, (2010) 摘要
  • Yarden, Y., and Ullrich, A., Growth factor receptor tyrosine kinases. Annu. Rev. Biochem. 57 , 443-478, (1988)
  • Heim, M., The Jak-STAT pathway: cytokine signalling from the receptor to the nucleus. J. Recept. Signal Transduct. Res. 19 , 75-120, (1999)
  • Stanley, E.R., Nicola, N., ed., Colony-stimulating factor-1. Guidebook to Cytokines and Their Receptors New York, N.Y. , (1994), 164-167
  • Sherr, C., and Stanley, E.R,, Sporn, M., and Roberts, A, ed., Colony-stimulating factor-1 (macrophage colony-stimulating factor). Peptide Growth Factors and their Receptors I New York , (1991), 667-698
  • Callard, R., and Gearing, A. The Cytokine Facts Book New York , (1994)
  • Rohrschneider, L.R., Nicola, N., ed., The macrophage colony-stimulating factor (M-CSF) receptor. Guidebook to Cytokines and Their Receptors New York , (1994), 168-170
  • Merck 14 ,5646

安全信息

GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Signal word Warning
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RTECSGI5500000
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 40 gm/kg
SEX/DURATION            : female 1-5 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   IMLED6 Immunology Letters.  (Elsevier Science Publishers B.V., POB 211, 100
   AE Amsterdam, Netherlands) V.1- 1979-  Volume(issue)/page/year: 23,65,1989

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