Fluorescein sodium salt 荧光素钠

CAS 518-47-8 MFCD00005050

化学结构图

518-47-8
SMILES: O=C1OC2(c3ccc([O-])cc3Oc3cc([O-])ccc32)c2ccccc21.[Na+].[Na+]

化学属性

Mol. FormulaC20H10Na2O5
Mol. Weight376.27
Melting Point320 °C
TSCAYes
Density1.6
Appearance 橙黄或浅橙红色结晶粉末。熔点314-316℃(分解)。溶于热乙醇、冰醋酸、碱溶液,呈绿色萤光,不溶于水、苯、氯仿和乙醚。
Solubilityinsoluble
Stability对湿度敏感

别名和识别编码

Chemical NameFluorescein sodium salt
MDL NumberMFCD00167039
CAS Number518-47-8
Synonym Fluorescein (sodium) {LY} Fluorescein (sodium) {} {LY} Fluorescein (sodium) {} {} {LY} Fluorescein (sodium) {} {} {} {LY} Fluorescein (sodium) {} {} {} {} {LY} Fluorescein (sodium) {} {} {} {} {} {LY} Fluorescein (sodium) {} {} {} {} {} {} {LY} Fluorescein (sodium) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Fluorescein (sodium) {} {} {} {} {} {} {} {} {LY} Fluorescein (sodium) {} {} {} {} {} {} {} {} {} {LY} Fluorescein (sodium) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Fluorescein (sodium) {} {} {} {} {} {} {} {} {} {} {} {LY} Fluorescein (sodium) {} {} {} {} {} {} {} {} {} {} {} {} {LY} Fluorescein (sodium) {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Fluorescein (sodium) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Fluorescein (sodium) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Fluorescein (sodium) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
PubChem Substance ID87569895
EC Number208-253-0
Beilstein Registry Number3833041
Merck Number4159
Chemical Name Translation荧光素钠
Reaxys-RN4117321
Wiswesser Line NotationT C666 BO EVJ IR BVQ& MQ &-NA- 2
LabNetwork Molecule IDLN01742321
Canonical SMILESO=C1OC2(C3=C(OC4=C2C=CC(O[Na])=C4)C=C(O[Na])C=C3)C5=C1C=CC=C5
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
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分类

  • {S
  • {SNA} E-F, Fluorescein and Derivatives, Fluorescent Labels, Stains & Dyes, A to Z, Stains and Dyes, 生化试剂, 细胞生物学, 荧光探针,标记,粒子和染色剂, 血液学和组织学
  • {SNA} Biochemicals and Reagents, E-F, Fluorescein and Derivatives, Fluorescent Labels, Fluorescent Probes, Labels, Particles and Stains, Stains & Dyes, A to Z, Stains and Dyes, 细胞生物学, 血液学和组织学
  • {SNA} Adsorption Indicators,
  • {SNA} Adsorption Indicators, Detection, Indicators, Titration, Wavelength Index, 分析/色谱, 分析试剂,
  • {SNA} Ads

产品应用

  • 荧光光度分析硫离子,试验溴,滴定氯、溴和碘。吸附指示剂,氧化还原指示剂。

相关文献及参考

  • Merck:14,4159 Beilstein:19,222
  • Merck:14,4159

安全信息

GHS Symbol
WGK Germany1
Hazard statements
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H303 May be harmfully swallowed 吞食可能有害
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RTECSLM5425000
Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P305+P351+P338
Signal word Warning
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护;
Risk Statements
  • R36 Irritating to eyes 刺激眼睛
Hazard Codes Xi
Storage condition Store at room temperature, keep dry and cool {LY} Store at room temperature, keep dry and cool {} {LY} Store at room temperature, keep dry and cool {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 19 gm/kg/79W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   GANNA2 Gann.  Japanese Journal of Cancer Research.  (Tokyo, Japan)  V.1-75,
   1907-84.  For publisher information, see JJCREP.  Volume(issue)/page/year:
   45,446,1954

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 16 gm/kg/1Y-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
   Tumorigenic - tumors at site of application
REFERENCE :
   GANNA2 Gann.  Japanese Journal of Cancer Research.  (Tokyo, Japan)  V.1-75,
   1907-84.  For publisher information, see JJCREP.  Volume(issue)/page/year:
   47,51,1956

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 7142 ug/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - hemorrhage
   Gastrointestinal - nausea or vomiting
REFERENCE :
   AJOPAA American Journal of Ophthalmology.  (Ophthalmic Pub. Co., 435 N.
   Michigan Ave., Suite 1415, Chicago, IL 60611)  Series 3: V.1-    1918-
   Volume(issue)/page/year: 103,111,1987

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   29,97,1974

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 6721 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   JOPRAJ Journal of Periodontology.  (American Academy of Periodontology, 211
   E. Chicago Ave., Chicago, IL 60611)  V.1-    1930- Volume(issue)/page/year:
   48,228,1977

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4738 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   JOPRAJ Journal of Periodontology.  (American Academy of Periodontology, 211
   E. Chicago Ave., Chicago, IL 60611)  V.1-    1930- Volume(issue)/page/year:

{ha

TYPE OF TEST            : DNA adduct
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 15 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 89,95,1981

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 50100 ug/L
REFERENCE :
   SCIEAS Science.  (American Assoc. for the Advancement of Science, 1333 H
   St., NW, Washington, DC 20005)  V.1-    1895-  Volume(issue)/page/year:
   236,933,1987

TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 200 mg/L
REFERENCE :
   SCIEAS Science.  (American Assoc. for the Advancement of Science, 1333 H
   St., NW, Washington, DC 20005)  V.1-    1895-  Volume(issue)/page/year:
   236,933,1987

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE                    : 933 mg/kg
SEX/DURATION            : female 5-8 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - postpartum
   Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4
   per # born alive)
REFERENCE :
   AJOPAA American Journal of Ophthalmology.  (Ophthalmic Pub. Co., 435 N.
   Michigan Ave., Suite 1415, Chicago, IL 60611)  Series 3: V.1-    1918-
   Volume(issue)/page/year: 84,847,1977

其他信息

  • 下游产品:赤藓红B --> 异硫氰酸荧光素 --> 3',6'-二氯荧光素
  • 上游原料:苯酐 --> 间苯二酚
  • 图谱信息:荧光素(2321-07-5)核磁图( 13 CNMR) 荧光素(2321-07-5)核磁图( 1 HNMR) 荧光素(2321-07-5)质谱(MS) 荧光素(2321-07-5)红外图谱(IR2) 荧光素(2321-07-5)红外图谱(IR1)
  • Sigma Aldrich:2321-07-5(sigmaaldrich)
  • MOL 文件:2321-07-5.mol
  • 方法一:用邻苯二甲酸酐与间苯二酚在硫酸参与下反应制得。
  • 色指数:45350
  • Acros Organics:荧光素 Fluorescein, pure(2321-07-5)
  • 并同时分解,能溶于热乙醇、冰乙酸、碳酸碱和氢氧化碱,并显亮绿色荧光,不溶于水、苯、氯仿和乙醚。最大吸收波长493.5、460nm。最小致死量(大鼠,腹腔)600mg/kg。
  • 用途二:荧光光度分析硫离子,试验溴,滴定氯、溴和碘。吸附指示剂,氧化还原指示剂。
  • 荧光素价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 71018814 荧光素;荧光橙 25g 22元 2011/04/16 F0095 荧光素 Fluorescein 500G 1490元 2011/04/16 F0095 荧光素 Fluorescein 25G 195元
  • F:10-21
  • 用途一:汞溴红的中间体。萤光光度分析试剂,测定氯、溴、碘、硫离子;氧化-还原指示试剂;生物染色剂。
  • MSDS 信息:2-(6-Hydroxy-3-oxo-(3H)-xanthen-9-yl)benzoic acid(2321-07-5).msds
  • Alfa Aesar:荧光素,90+% Fluorescein, 90+%(2321-07-5)
  • TCI Shanghai:荧光素 Fluorescein(2321-07-5)

系列性分类


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