α1-39-Corticotropin(swine) α1-39-促肾上腺皮质激素(猪)

CAS 9061-27-2 MFCD00167432

化学结构图

9061-27-2
SMILES: CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1c[n]c[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(O)=O

化学属性

Mol. Weight4567.15
Mol. FormulaC210H314N56O57S

别名和识别编码

Synonym Corticotropin A Adrenocorticotropic Hormone Fragment 1-39 Corticotropin A Adrenocorticotropic Hormone Fragment 1-39 Adrenocorticotropic Hormone from porcine pituitary
MDL NumberMFCD00167432
CAS Number9061-27-2
EC Number232-946-7
Chemical Nameα1-39-Corticotropin(swine)
Chemical Name Translationα1-39-促肾上腺皮质激素(猪)
InChIKeyXFBDTKGDXZDJAN-WODOTNDISA-N
PubChem Substance ID16157885
InChIInChI=1S/C210H314N56O57S/c1-110(2)91-143(189(304)234-116(12)173(288)237-135(68-73-163(275)276)178(293)233-117(13)174(289)256-151(95-119-43-20-16-21-44-119)205(320)265-88-37-56-155(265)196(311)254-144(92-111(3)4)190(305)243-139(72-77-167(283)284)186(301)258-153(207(322)323)97-120-45-22-17-23-46-120)249-184(299)138(71-76-166(281)282)244-194(309)150(101-168(285)286)253-183(298)136(69-74-164(277)278)238-172(287)115(11)232-160(272)104-228-177(292)149(100-159(216)271)255-197(312)156-57-38-89-266(156)206(321)152(96-122-62-66-126(270)67-63-122)257-202(317)170(113(7)8)260-188(303)132(51-28-32-81-213)246-201(316)171(114(9)10)262-199(314)158-59-40-87-264(158)204(319)142(55-36-85-226-210(221)222)247-181(296)133(53-34-83-224-208(217)218)240-180(295)131(50-27-31-80-212)239-179(294)130(49-26-30-79-211)235-161(273)106-230-200(315)169(112(5)6)261-198(313)157-58-39-86-263(157)203(318)141(52-29-33-82-214)236-162(274)105-229-176(291)147(98-123-102-227-129-48-25-24-47-127(123)129)251-182(297)134(54-35-84-2
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分类

  • Adrenocorticotrophic Hormone (ACTH), Adrenocorticotropic Hormones (ACTH), Cell Biology, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, Hormones, Peptides and Proteins, Peptides for Cell Biology, Pituitary Hormones
  • {SNA} Adrenocorticotrophic Hormone (ACTH), Adrenocorticotropic Hormones (ACTH), Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, Hormones, Peptides and Proteins, Peptides for Cell Biology, Pituitary Hormones, 细胞生物学
  • {SNA} Adrenocorticotrophic Hormone (ACTH), Adrenocorticotropic Hormones (ACTH), Cytokines, Growth Factors and Hormones, Hormones, Peptides and Proteins,
  • {SNA} Adrenocorticotrophic Hormone (ACTH),
  • {SNA} Adrenocorticotrophic Hormone (ACTH),

相关文献及参考

  • Lay, D.C., et al., Prenatal stress effects on pig development and response to weaning. J. Anim. Sci. 86 , 1316-24, (2008) 摘要
  • Auperin, B., and Geslin, M., Plasma cortisol response to stress in juvenile rainbow trout is influenced by their life history during early development and by egg cortisol content. Gen. Comp. Endocrinol. 158 , 234-9, (2008) 摘要
  • Sabban, E.L., et al., Kinetics and persistence of cardiovascular and locomotor effects of immobilization stress and influence of ACTH treatment. Neurochem. Int. 89 , 98-108, (2009) 摘要
  • Yates, D.T., et al., Technical Note: Comparison Of Salivary And Serum Cortisol Concentrations After Adrenocorticotropic Hormone Challenge In Ewes. J. Anim. Sci. 88 , 599-603, (2010) 摘要
  • Pereira, R.J., et al., Annual Profile Of Fecal Androgen And Glucocorticoid Levels In Free-living Male American Kestrels From Southern Mid-latitude Areas. Gen. Comp. Endocrinol. 166 , 94-103, (2010) 摘要

安全信息

GHS Symbol
WGK Germany3
Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
Signal word Warning
Hazard statements
  • H332 Harmful if inhaled 吸入有害
  • H351 Suspected of causing cancer 怀疑致癌
  • H302 Harmful if swallowed 吞食有害
  • H312 Harmful in contact with skin 皮肤接触有害
Hazard Codes Xn
Personal Protective Equipment Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Safety Statements
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
  • S22 Do not breathe dust 不要吸入粉尘;
Risk Statements
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
  • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用

系列性分类


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