Conotoxin GI

CAS 76862-65-2 MFCD00167555

化学结构图

76862-65-2
SMILES: C[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(N)=O)NC(=O)[C@@H]2CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC3C=CC(O)=CC=3)NC(=O)[C@H](CC3=CNC=N3)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CSSC[C@H](NC(=O)[C@@H](N)CCC(O)=O)C(=O)N2)NC1=O)C(N)=O

化学属性

Mol. FormulaC55H80N20O18S4
Mol. Weight1437.61

别名和识别编码

Chemical NameConotoxin GI
MDL NumberMFCD00167555
PubChem Substance ID24893090
CAS Number76862-65-2
Synonym Conotoxin GI Myotoxin from Conus geographus venom
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分类

  • Bioactive Small Molecules, CI-CY, Cell Biology, Cell Signaling and Neuroscience, Ion Channel Modulating Peptides, Ion Channels, Monovalent Ion Channels, Other Sodium Channel Modulators, Peptide Toxins, Peptides and Proteins, Peptides for Cell Biology, Snail, Sodium Channel Modulators, Toxins and Venoms, Voltage-gated Ion Channels
  • {SNA} Bioactive Small Molecules, CI-CY, Cell Biology, Cell Signaling and Neuroscience, Ion Channel Modulating Peptides, Ion Channels, Monovalent Ion Channels, Other Sodium Channel Modulators, Peptide Toxins, Pepti

相关文献及参考

  • Gray, W.R., et al. J. Biol. Chem. 256 , 4734, (1981) 摘要

安全信息

WGK Germany3
RTECSGL1500000
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 12 ug/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   ABBIA4 Archives of Biochemistry and Biophysics.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802)  V.31-    1951-  Volume(issue)/page/year:
   190,539,1978

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Ion Channels - Cell Signaling and Neuroscience
  5. Voltage-gated Ion Channels - Ion Channels
  6. Monovalent Ion Channels - Voltage-gated Ion Channels
  7. Sodium Channel Modulators - Monovalent Ion Channels
  8. Other Sodium Channel Modulators - Sodium Channel Modulators
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Ion Channels - Cell Signaling and Neuroscience
  5. Voltage-gated Ion Channels - Ion Channels
  6. Monovalent Ion Channels - Voltage-gated Ion Channels
  7. Sodium Channel Modulators - Monovalent Ion Channels
  8. Other Sodium Channel Modulators - Sodium Channel Modulators
  1. Functional Group 官能团索引
  2. disulfide

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