LY83583 6-苯胺基-5,8-喹啉二酮

CAS 91300-60-6 MFCD00210756

化学结构图

91300-60-6
SMILES: O=C1C(=CC(=O)C2N=CC=CC1=2)NC1C=CC=CC=1

化学属性

Mol. FormulaC15H10N2O2
Mol. Weight250.25

别名和识别编码

Chemical NameLY83583
CAS Number91300-60-6
Synonym 5,8-Dihydro-5,8-dioxo-6-(phenylamino)quinoline 6-(Phenylamino)-5,8-quinolinedione 6-(Phenylamino)-5,8-quinolinedione LY-83,583 LY83583 6-(phenylamino)-5,8-quinolinedione 6-Anilinoquinoline-5,8-quinone LY 83583 LY-83,583 LY83583
MDL NumberMFCD00210756
PubChem Substance ID24891108
Chemical Name Translation6-苯胺基-5,8-喹啉二酮
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分类

  • {SNA} AN-AZ, Bioactive Small Molecule Alphabetical Index, Cyclic Nucleotide Metabolism, G Proteins and Cyclic Nucleotides, Guanylyl Cyclase Inhibitors, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
  • Inhibitors
  • Nitric Oxide Reagents
  • Heterocycles
  • {SNA} AN-AZ, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,

产品应用

  • Inhibits nitric-oxide-induced activation of soluble guanylate cyclase (IC50=2?M) in a dose-dependent and reversible manner. It blocks acetylcholine induced vasorelaxation. Also an inhibitor of anti

相关文献及参考

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安全信息

GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
WGK Germany3
Signal word Warning
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
Hazard Codes Xi
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

系列性分类


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