Norcantharidin 去甲斑蝥素

CAS 29745-04-8 MFCD00213361

化学结构图

29745-04-8
SMILES: O=C1OC(=O)C2C1[C@@H]1CC[C@H]2O1 |&1:7,10|

化学属性

Mol. FormulaC8H8O4
Mol. Weight168
Melting Point113.0 to 117.0 deg-C
TSCANo

别名和识别编码

Chemical NameNorcantharidin
MDL NumberMFCD00213361
Synonym 4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-, Endothall anhydride Norcantharidin exo-3,6-Epoxyhexahydrophthalic anhydride exo-3,6-Epoxyhexahydrophthalic anhydrideNorcantharadin
CAS Number29745-04-8
Beilstein Registry Number0084287
PubChem Substance ID253659717
Chemical Name Translation去甲斑蝥素
Reaxys-RN84287
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分类

  • {SNA} Bioactive Small Molecule Alphabetical Index, Kinase/Phosphatase Biology, N, Phosphatase Inhibitors, Protein Phosphatase 1 (PP1), Serine/Threonine Kinase Biology, Serine/Threonine Phosphatase Inhibitors, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
  • {SNA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Kinase/Phosphatase Biology, N, Phosphatase Inhibitors, Protein Phosphatase 1 (PP1), Serine/Threonine Kinase Biology, Serine/Threonine Phosphatase Inhibitors
  • {SNA} Bioactive Small Molecules, Cell Signaling and Neuroscience, Kinase/Phosphatase Biology, N, Phosphatase Inhibitors,

安全信息

RTECSRN8400000
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S37 Wear suitable gloves 戴适当手套；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Storage condition Moisture Sensitive
WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
GHS Symbol
Signal word
Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P332+P313
  • P305+P351+P338+P337+P313
  • P302+P350
  • P337+P313
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JAFCAU Journal of Agricultural and Food Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC
   20037)  V.1-    1953-  Volume(issue)/page/year: 35,823,1987

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Bioactive Small Molecules - Cell Biology
  4. N - Bioactive Small Molecules
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Kinase/Phosphatase Biology - Cell Signaling and Neuroscience
  5. Serine/Threonine Kinase Biology - Kinase/Phosphatase Biology
  6. Serine/Threonine Phosphatase Inhibitors - Serine/Threonine Kinase Biology
  7. Protein Phosphatase 1 (PP1) - Serine/Threonine Phosphatase Inhibitors
  1. Functional Group 官能团索引
  2. carboxylic acid anhydride

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