N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide

CAS 120615-25-0 MFCD00269886

化学结构图

120615-25-0
SMILES: NCCNS(=O)(=O)C1=CC=C(Cl)C2=CC=NC=C12

化学属性

Mol. FormulaC11H12ClN3O2S
Mol. Weight286

别名和识别编码

Chemical NameN-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide
Chemical Name TranslationN-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide
MDL Number
CAS Number120615-25-0
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相关文献及参考

  • [2]. Mark G. Frattini, et al. Small Molecule Inhibition of Cdc7, a Key Cell Cycle Regulator and Novel Therapeutic Target, Successfully Inhibits Leukemia Cell Growth in Vitro and in Vivo. Blood (2008) 112 (11): 2668.
  • [3]. Chijiwa T, et al. A newly synthesized selective casein kinase I inhibitor, N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide, and affinity purification of casein kinase I from bovine testis. J Biol Chem. 1989 Mar 25;264(9):4924-7.
  • [4]. Rena G, et al. D4476, a cell-permeant inhibitor of CK1, suppresses the site-specific phosphorylation and nuclear exclusion of FOXO1a. EMBO Rep. 2004 Jan;5(1):60-5.
  • [1]. Osakada F, et al. In vitro differentiation of retinal cells from human pluripotent stem cells by small-molecule induction. J Cell Sci. 2009 Sep 1;122(Pt 17):
  • [1]. Osakada F, et al. In vitro differentiation of retinal cells from human pluripotent stem cells by small-molecule induction. J Cell Sci. 2009 Sep 1;122(Pt 17):3169-79.

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